Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for Neuroscience

Cat.No. 产品名称 Information
GC52324 3-(3-Hydroxyphenyl)propionic Acid sulfate

3-HPPA sulfate
A metabolite of certain phenols and glycosides
GC42198 3-(4-Chlorophenyl)-4-hydroxybutyric Acid (sodium salt)

γ-Hydroxybaclofen
An inactive metabolite of baclofen
GC46583 3-Amino-2,6-Piperidinedione

3-氨基-2,6-哌啶二酮
An active metabolite of (±)-thalidomide
GC52129 3-Amino-5-hydroxybenzoic Acid

3-氨基-5-羟基苯甲酸
A biosynthetic precursor to ansamycin antibiotics
GC42248 3-Aminopropylphosphonic Acid

3-氨基丙烷-1-磷酸
A partial agonist of GABA_B receptors
GC11757 3-Bromocytisine

3-Br-cytisine
3-Bromocytisine (3-Br-cytisine) 是一种有效的 nACh 受体激动剂，对 hα4β4、hα4β2 和 hα7-nACh 的 IC50 分别为 0.28、0.30 和 31.6 nM。
GC12641 3-CPMT dopamine uptake inhibitor
GC42258 3-Cysteinylacetaminophen (trifluoroacetate salt)

3-(cysteine-S-yl)acetaminophen, APAP-Cys
An acetaminophen-protein adduct
GC60499 3-Hydroxy agomelatine

阿戈美拉汀杂质
3-Hydroxyagomelatine是Agomelatine的代谢产物。3-Hydroxyagomelatine是5-HT2C受体拮抗剂，IC50为3.2μM，Ki为1.8μM。
GC68328 3-Hydroxy agomelatine-d3 3-Hydroxy agomelatine D3 是 3-Hydroxy agomelatine 的氘代物。3-Hydroxy agomelatine 是 5-HT2C 受体拮抗剂，IC50 为 3.2 μM，Ki 为 1.8 μM。
GC42274 3-hydroxy Darifenacin

UK 148993
A metabolite of darifenacin
GC41565 3-hydroxy Medetomidine

羟基美托咪定
A metabolite of medetomidine
GC18311 3-hydroxy Octanoic Acid

3-羟基辛酸
A hydroxy fatty acid
GC40487 3-hydroxy Undecanoic Acid

3-羟基十一烷酸
A hydroxy fatty acid
GC90789 3-hydroxy Xylazine
一种二甲基苯乙胺的代谢产物。
GC52048 3-hydroxy-4-Methoxyphenethylamine (hydrochloride)

4-甲氧基多巴胺盐酸盐
A metabolite of dopamine
GC45336 3-hydroxy-DL-Kynurenine

DL-3-羟基犬尿氨酸,DL-3-Hydroxykynurenine
3-hydroxy-DL-Kynurenine是一种潜在的内源性神经毒素，以剂量依赖方式显著抑制CD4⁺ T细胞增殖，IC₅₀约为70μM。
GC42294 3-Iodothyronamine (hydrochloride)

T1AM
A metabolite of thyroxine
GC11223 3-MATIDA mGlu1 receptor antagonist
GC49869 3-Methoxytyrosine

2-氨基-3-(4-羟基-3-甲氧基苯基)丙酸
An active metabolite of L-DOPA
GC49149 3-Methylglutaconic Acid

3-甲基戊烯二酸
A branched-chain organic acid
GC42307 3-O-methyl-L-DOPA (hydrate)

3-O-甲基-L-多巴一水合物
A metabolite of L-DOPA
GC60505 3-O-Methyldopa

(S)-2-氨基-3-(4-羟基-3-甲氧苯基)丙酸,3-Methoxy-L-tyrosine; 3-O-Methyl-L-DOPA
3-O-Methyldopa(3-Methoxy-L-tyrosine)是一种由邻苯二酚-O-甲基转移酶(COMT)形成的L-DOPA代谢物。3-O-Methyldopa竞争性抑制L-DOPA和多巴胺(dopamine)的药效学。
GC60506 3-O-Methyldopa D3

3-甲氧基-L-酪氨酸-D3,3-Methoxy-L-tyrosine-d3; 3-O-Methyl-L-DOPA-d3
3-O-MethyldopaD3(3-Methoxy-L-tyrosineD3)是3-O-Methyldopa的氘代物。3-O-Methyldopa是一种由邻苯二酚-O-甲基转移酶(COMT)形成的L-DOPA代谢物。3-O-Methyldopa竞争性抑制L-DOPA和多巴胺(dopamine)的药效学。
GC10484 3-pyr-Cytisine
α4β2 receptors agonist
GC52391 306-O12B-3 An ionizable cationic lipidoid
GC18817 3β-hydroxy-5-Cholestenoic Acid

3β-hydroxy-5-CA, Cholesterol-26-carboxylic Acid
An active cholesterol metabolite
GC70850 4′-Demethylnobiletin 4′-Demethylnobiletin是一种生物活性代谢产物，可激活PKA/ERK/CREB信号通路，并通过刺激ERK信号传导逆转与NMDA受体拮抗相关的记忆损伤。
GC49367 4’-hydroxy Atomoxetine Glucuronide (hydrate) A metabolite of atomoxetine
GC49252 4’-hydroxy Trazodone A metabolite of trazodone
GC40768 4(Z),7(Z),10(Z),13(Z),16(Z)-Nonadecapentaenoic Acid An unusual PUFA
GC45340 4(Z),7(Z),10(Z),13(Z)-Hexadecatetraenoic Acid

顺-4,顺-7,顺-10,顺-13-十六碳四烯酸
An unusual PUFA
GC62799 4,4-Diphenylbutylamine hydrochloride

4,4-二苯基丁胺(盐酸盐)
4,4-Diphenylbutylamine 对 5-HT2A 和 H1 受体的 Ki 值分别为 2589 和 1670 nM。
GC49752 4,5-Desisopropylidene Topiramate

4,5-Desisopropylidene TPM
An inactive metabolite of topiramate
GC30952 4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine 4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine是一种有效的淀粉样蛋白显像剂，其与淀粉样蛋白Amyloid-β(1-40)结合的KD值为1.7nM。
GC31208 4-(6-Bromo-2-benzothiazolyl)benzenamine 4-(6-Bromo-2-benzothiazolyl)benzenamine是β-淀粉样蛋白(β-amyloid)的PET（正电子发射断层扫描）示踪剂，可用于诊断神经疾病，如阿尔茨海默病和唐氏综合征。
GC40045 4-(Dimethylamino)-1-methylpyridinium (iodide) A pyridinium salt
GC91680 4-Acetamido Antipyrine

4-AAAP,NSC 331807
4-Acetamido antipyrine (4-AAAP) is an active metabolite of the non-opioid analgesic and antipyretic prodrug metamizole .
GC33504 4-Acetamidobutanoic acid (N-acetyl GABA)

4-乙酰氨基丁酸,N-acetyl GABA
A GABA derivative
GC15383 4-Acetyl-1,1-dimethylpiperazinium iodide nicotinic agonist
GC42338 4-Aminobenzoic Acid hydrazide

4-氨基苯甲酰肼,p-Aminobenzohydrazide; p-Aminobenzoic acid hydrazide
An MPO inhibitor
GC49657 4-chloro Trazodone isomer (hydrochloride)

曲唑酮相关物质C
An isomer of trazodone
GC13348 4-DAMP

4-二苯乙酰氧基-N-甲基-哌啶甲碘化物,4-DAMP methiodide
An antagonist of the muscarinic M₃ receptor
GC42373 4-epi Minocycline

4-表米诺环素

A degradation product and potential impurity of minocycline
GC42402 4-hydroxy (S)-Duloxetine β-D-Glucuronide (sodium salt)

LY550408
An inactive metabolite of (S)-duloxetine
GC48824 4-hydroxy Estrone

4-羟基雌酮; 4-OHE1
A metabolite of estrone
GC42411 4-hydroxy Nonenal Alkyne

Click Tag 4HNE Alkyne

4-HNE modified for click chemistry
GC40879 4-hydroxy Solifenacin N-oxide An N-oxide form of 4-hydroxy solifenacin
GC90790 4-hydroxy Xylazine O-Glucuronide (lithium salt)

p-hydroxy Xylazine O-Glucuronide, para-hydroxy Xylazine O-Glucuronide

一种二甲基苯乙胺的代谢产物。
GC91641 4-Hydroxy-1-(2-phenylethyl)piperidine 4-Hydroxy-1-(2-phenylethyl)piperidine is a building block that has been used in the synthesis of ligands of the muscarinic acetylcholine receptor (mAChR) or sigma non-opioid intracellular receptor 1 (σ1 receptor).