Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for Neuroscience

Cat.No. 产品名称 Information
GC41156 5-Octyl D-glutamate

5-Octyl ester D-glutamatic acid
A cell-permeable form of D-glutamate
GC41094 5-trans Latanoprost

反式拉坦前列素
An analytical standard
GC41228 5-trans Latanoprost (free acid)

5,6trans Latanoprost (free acid)
Trans isomer of latanoprost (free acid)
GC49438 5-trans-17-phenyl trinor Prostaglandin F2α

贝美前列素2
The 5-trans isomer of 17-phenyl trinor PGF_2α
GC31296 5HT6-ligand-1 5HT6-ligand-1是有效的5-HT6受体配体，与其结合的Ki值为1.43nM。
GC18176 5α,6β-Dihydroxycholestanol

胆甾烷-3,5,6-三醇
An oxysterol metabolite of cholesterol
GC30943 6,2'-Dihydroxyflavone

6,2-二羟基黄酮
6,2'-Dihydroxyflavone是一个新型的GABAA受体拮抗剂。
GC46720 6,9-Dichloro-1,2,3,4-tetrahydroacridine

NSC 1227
A synthetic intermediate in the synthesis of AChE inhibitors
GC42572 6-Amino-8-trifluoromethylphenanthridine

6A-8tFP
An antiprion agent
GC40479 6-Aminophenanthridine

6AP
An antiprion agent
GC14000 6-fluoro-DL-Tryptophan

6-氟-DL-色氨酸,DL-6-Fluorotryptophan,NSC 9364
A serotonin synthesis inhibitor
GC42580 6-hydroxy Chlorzoxazone

6-.羟基氯唑沙宗,NSC 24955
A metabolite of chlorzoxazone
GC49183 6-hydroxy Etodolac

6-羟基依托度酸
A metabolite of etodolac
GC16267 6-Hydroxydopamine hydrobromide

6-羟基多巴胺氢溴酸盐; 6-Hydroxydopamine hydrobromide; 6-OHDA hydrobromide
6-Hydroxydopamine hydrobromide (6-OHDA) 是儿茶酚胺、多巴胺和去甲肾上腺素的结构类似物，对儿茶酚胺能神经元发挥毒性作用。
GC16153 6-methoxy Naphthalene Acetic Acid

6-甲基萘乙酸,6-MNA
A non-selective COX inhibitor
GC31309 6-Methoxy-2-naphthoic acid (Naproxen impurity O)

6-甲氧基-2-萘甲酸,Naproxen impurity O
An active metabolite of nabumetone
GC30898 6-Methylflavone

6-甲基黄酮
6-methylflavone是α1β2γ2L和α1β2GABAA受体的激活剂。
GC42584 6-O-desmethyl Donepezil

6-O-去甲基多奈哌齐
An active metabolite of donepezil
GC10781 7-Chlorokynurenic acid

7-氯犬尿酸,7-CKA
A glycine-site selective NMDA receptor antagonist
GC11395 7-Chlorokynurenic acid sodium salt

7-氯犬尿喹啉酸钠盐,7-CKA sodium salt
A glycine-site selective NMDA receptor antagonist
GC46242 7-dehydro Cholesterol-d7

7-去氢胆固醇 d7
An internal standard for the quantification of 7-dehydro cholesterol
GC48649 7-hydroxy Chlorpromazine (hydrochloride) An active metabolite of chlorpromazine
GC35192 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone

3,4-二氢-7-羟基-2(1H)-喹啉酮,3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
7-Hydroxy-3,4-dihydrocarbostyril is used as the materials for the organic synthesis intermediates.
GC16574 7-Hydroxy-DPAT hydrobromide A dopamine D₃ receptor agonist
GC16916 7-Hydroxy-PIPAT maleate D3 receptor agonist
GC63640 7-Hydroxyflavone

7羟基黄酮
A flavonoid with diverse biological activities
GC40572 7-keto Cholesterol

胆甾-3-羟基-5-烯-7-酮,SC-4722, 7-酮胆固醇
7-keto Cholesterol是一种与血管疾病相关的主要氧甾醇，广泛存在于动脉粥样硬化斑块中，具有比胆固醇更强的致动脉粥样硬化作用。
GC46241 7-keto Cholesterol-d7

7-酮基胆固醇-D7,7-oxo Cholesterol-d7
An internal standard for the quantification of 7-keto cholesterol
GC48880 7-Methoxyflavone

7-甲氧基黄酮
A flavone with diverse biological activities
GC15338 8,11,14-Eicosatriynoic Acid

8,11,14-ETI
A cyclooxygenase and lipoxygenase inhibitor
GC40587 8,12-iso-iPF2α-VI

8,12-iso-Isoprostane-F2α-VI, 12-iso-5,6E,14Z-PGF2α, 125,6E,14ZProstaglandin F2α
An isoprostane used as a biomarker for oxidative stress
GC90867 8-bromo NAD+ (sodium salt)

N(8-bromo-A)D+, 8-bromo Nicotinamide adenine dinucleotide

8-溴-cADPR的前药形式
GC49017 8-hydroxy Amoxapine A metabolite of amoxapine
GC42626 8-hydroxy Efavirenz

8-羟基依法韦伦
A major metabolite of efavirenz
GC18654 8-hydroxy Loxapine

8-OH Loxapine
A loxapine metabolite
GC49544 8-hydroxy Mirtazapine

8-羟基米安色林
A metabolite of mirtazapine
GC14966 8-Hydroxy-DPAT hydrobromide

7-(二丙基氨基)-5,6,7,8-四氢-1-萘酚氢溴酸盐,8-Hydroxy-DPAT hydrobromide
A 5-HT_1A receptor agonist
GC12427 8-Hydroxy-PIPAT oxalate 5-HT1A receptor agonist
GC40759 8-methyl Nonanoic Acid

8-甲基壬酸,Isocapric Acid
A precursor of capsaicin
GC30888 8-OH-DPAT (8-Hydroxy-DPAT)

8-Hydroxy-DPAT

8-OH-DPAT 是5-HT1A 激动剂， pIC50 值为 8.19 ，此外8-OH-DPAT对5-HT1B(pIC50 , 5.42)和5-HT (pIC50 <5)受体亲和力都很弱。
GC46753 9(S),12(S),13(S)-TriHOME

(-)-Pinellic Acid, 9S,12S,13S-Pinellic Acid
An oxylipin
GC42640 9(Z),12(Z),15(Z),18(Z),21(Z)-Tetracosapentaenoic Acid

all-cis-9,12,15,18,21-Tetracosapentaenoic Acid
A very long-chain polyunsaturated fatty acid
GC14302 9,12-Octadecadiynoic Acid

Ro 3-1314
An inhibitor of both COX and lipoxygenase
GC91242 9-keto Latanoprost
一种拉坦前列素的衍生物。
GC35012 [10]-Shogaol

10-姜烯酚
A phenol with diverse biological activities
GC35013 [8]-Shogaol

8-姜烯酚
[8]-Shogaol，生姜中的一种刺激性酚类化合物，具有抗血小板活性 (IC50=5 μM) 和抑制 COX-2 (IC50=17.5 μM)。[8]-Shogaol 诱导人白血病细胞凋亡。
GC52414 [Ala17]-MCH (trifluoroacetate salt)

Ala17-Melanin-Concentrating Hormone
An MCH-derived peptide and MCH receptor agonist
GC15122 [bAla8]-Neurokinin A(4-10)

MEN 10210
[bAla8]-Neurokinin A(4-10) 是一种神经激肽 2 (NK2) 受体激动剂。
GC52388 [D-Lys3]-GHRP-6 (trifluoroacetate salt)

D-Lys3-Growth Hormone Releasing Peptide 6, His-D-Trp-D-Lys-Trp-D-Phe-Lys-NH2
An antagonist of GHS-R1a
GC72115 [D-Pro2] Spantide I TFA [D-Pro2] Spantide I TFA是Spantide的类似物。