Endocrinology and Hormones(内分泌和激素)

Endocrinology and Hormones

The endocrine system is an information signaling system that coordinates most bodily functions. It senses environmental changes and secretes corresponding hormones to coordinate metabolism, maintain homeostasis, and regulate growth and development.read more

Products for Endocrinology and Hormones

Cat.No. 产品名称 Information
GC49838 α-Cortolone

Β-皮甾酮四醇
A metabolite of cortisol
GC48292 α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)

Α-促黑激素,α-Melanocyte-Stimulating Hormone TFA
A peptide hormone
GC45226 β-BHC

β-HCH, β-Hexachlorocyclohexane, β-Lindane
β-BHC is an isomer of the organochlorine pesticide γ-lindane that is a potential impurity found in commercial preparations of lindane.
GC60391 β-Casomorphin, bovine TFA

β-Casomorphin-7 (bovine) (TFA); Bovine β-casomorphin-7 TFA
β-casomorphin, bovine TFA (β-Casomorphin-7 (bovine) TFA) 是阿片 (opioid) 活性的多肽，与阿片受体结合的 IC50 值为 14 μM。
GC61484 β-Casomorphin, human TFA

Human β-casomorphin 7 TFA
β-Casomorphin,humanTFA(Humanβ-casomorphin7TFA)是一种阿片样肽，作为opioid受体激动剂。
GC90496 β-Cortolone

20β-Cortolone, NSC 56997

一种皮质醇的代谢产物。
GC45236 β-Endorphin (rat)

Β-内啡肽,鼠
An opioid neuropeptide
GC52494 β-Endorphin (rat) (trifluoroacetate salt) An opioid neuropeptide
GC38005 β-Endorphin, equine β-Endorphin, equine 为具有镇痛作用的内源性阿片类多肽。
GC38030 β-Endorphin, equine (TFA) β-Endorphin, equine (TFA) 是一种内源性阿片类多肽，对 μ 和 δ 阿片受体 (μ/δ opioid receptors) 有很强的亲和性。具有止痛作用。
GC72132 β-Endorphin, equine TFA β-Endorphin, equine TFA是一种内源性阿片肽，与μ/δ阿片受体都具有高亲和力。
GC45238 δ14-Triamcinolone acetonide

曲安奈德杂质1
A potential impurity found in commercial triamcinolone acetonide preparations
GC45239 δ4-Abiraterone

阿比特龙代谢物,Δ4-Abiraterone; CB-7627; Abiraterone D4A metabolite
An active metabolite of abiraterone
GC15975 α-Estradiol

α-雌二醇; Alfatradiol; Epiestradiol; Epiestrol
A weak estrogen with neuroprotective effects
GC33736 β-Casomorphin, bovine (β-Casomorphin-7 (bovine))

Β-酪啡肽-7,β-Casomorphin-7 (bovine); Bovine β-casomorphin-7
β-Casomorphin, bovine (β-Casomorphin-7 (bovine)) (β-Casomorphin-7 (bovine) ) 是一种阿片肽，在阿片受体结合试验中的 IC50 为 14 μM。
GC33784 β-Casomorphin, human (Human β-casomorphin 7)

Human β-casomorphin 7
是一种阿片肽，作为阿片受体的激动剂。
GC31117 β-Endorphin, human

β-内啡肽,人
β-Endorphin,human是存在于垂体和下丘脑中的重要的内源性肽，为阿片样(opioid)受体激动剂，尤其对μ-opioid受体和δ-opioid受体的亲和性更高；β-Endorphin,human具有镇痛的功效。
GC15938 β-Funaltrexamine hydrochloride
μ opioid receptor antagonist
GC45713 (±)-α-Tocopherol Acetate

生育酚乙酸酯; (±)-Vitamin E acetate
An acetate form of (±)-α-tocopherol
GC46313 (±)-α-Tocopherol Acetate-d3

all-rac-α-Tocopherol Acetate-d3, DL-α-Tocopherol Acetate-d3, DL-Vitamin E Acetate-d3
A neuropeptide with diverse biological activities
GC41671 (±)-Equol 4'-sulfate (sodium salt)

R,S-Equol 4'-Sulfate
A metabolite of (±)-equol
GC64007 (±)-U-50488 hydrate hydrochloride

(±)-Trans-(1R,2R)-U-50488 hydrate hydrochloride
(±)-U-50488 ((±)-Trans-(1R,2R)-U-50488) hydrate hydrochloride 是一种 κ 阿片受体 (κ opioid receptor) 激动剂。
GC15885 (±)-U-50488 hydrochloride

(±)-Trans-(1R,2R)-U-50488 hydrochloride
An Analytical Reference Material
GC34960 (+)-Talarozole (+)-Talarozole 是视黄酸代谢的有效抑制剂，来自专利 WO 1997049704 A1。
GC12688 (+)-U-50488 hydrochloride

(+)-Trans-(1R,2R)-U-50488 hydrochloride
An Analytical Reference Material
GC31386 (-)-PX20606 trans isomer ((-)-PX-102 trans isomer)

PX-20606手性,(-)-PX-102 trans isomer; (-)-PX-104
(-)-PX20606 trans isomer ((-)-PX-102 trans isomer) 是一种 FXR 激动剂，在 FRET 和 M1H 试验中对 FXR 的 EC50 分别为 18 和 29 nM。
GC15944 (-)-U-50488 hydrochloride

(-)-Trans-(1S,2S)-U-50488 hydrochloride
(-)-U-50488 hydrochloride（(-)-U-50488盐酸盐）是一种选择性kappa阿片受体（KOR）激动剂，IC₅₀值为 0.25μM。
GC70081 (1R,2R)-U-50488 hydrochloride (1R,2R)-U-50488 hydrochloride 是 (±)-U-50488 hydrochloride 的绝对构型。(±)-U-50488 hydrochloride 是一种 κ 阿片受体 (κ opioid receptor) 激动剂。
GC34965 (20S)-Protopanaxatriol

20 (S)-原人参三醇; 20(S)-APPT; g-PPT
An active ginsenoside metabolite
GA20156 (D-Ser(tBu)⁶,Azagly¹⁰)-LHRH (free base)

戈舍瑞林; ICI 118630
GC41699 (Des-octanoyl)-Ghrelin (human) (trifluoroacetate salt) A peptide hormone
GC15373 (E)-2-Decenoic acid

反式-2-癸烯酸,trans-2-Decenoic acid
An unsaturated fatty acid found in royal jelly
GC46336 (E)-Guggulsterone

孕二烯二酮,(E)-Guggulsterone
A farnesoid X receptor antagonist
GC49189 (E/Z)-4-hydroxy Tamoxifen-d5

Afimoxifene-d5, 4-OHT-d5
An internal standard for the quantification of (E/Z)-4-hydroxy tamoxifen
GC91543 (E/Z)-Droloxifene

3-Hydroxytamoxifen
(E/Z)-Droloxifene is a mixture of (E)-droloxifene, a selective estrogen receptor modulator (SERM), and (Z)-droloxifene.
GC40833 (E/Z)-Endoxifen

N-去甲基-4-羟基-
An active metabolite of tamoxifen
GC61491 (R)-Bicalutamide

(R)-比卡鲁胺
(R)-Bicalutamide是Bicalutamide的R型对映体。(R)-Bicalutamide是一种雄激素受体(AR)拮抗剂，具有抗肿瘤活性。(R)-Bicalutamide广泛用于前列腺癌的研究。
GC13373 (R)-DPN R)-DPN (compound 3) 是一种选择性 ERβ 配体，对 ERα 和 ERβ 的 EC50 分别为 2.9 和 0.8 nM。
GC73509 (R)-SKBG-1 (R)-SKBG-1是rna结合蛋白NONO抑制剂。
GC30710 (R)-UT-155 (R)-UT-155(compound11)是一种选择性的、雄激素受体降解物(SARD)配体。活性低于S型异构体。
GC18003 (R,R)-THC (R,R)-THC 是 ERα 激动剂和 ERβ 拮抗剂，对 ERα 和 ERβ 的 Kis 分别为 9.0 nM 和 3.6 nM。
GC52185 (R,S)-Anatabine-d4

RAC-盐酸安那他品-D4
An internal standard for the quantification of (R,S)-anatabine
GC63292 (rac)-PF-998425 (rac)-PF-998425 是一种有效、选择性的非甾体雄激素受体 (AR) 拮抗剂。(rac)-PF-998425 在 AR 结合和细胞分析中的 IC50 值分别为 26 和 90 nM。(rac)-PF-998425 具有用于研究雄激素性脱发的潜力。
GC69798 (Rac)-SNC80

(Rac)-NIH 10815
(Rac)-SNC80 是 SNC80 的外消旋体。SNC80 (NIH 10815) 是一种有效的，高度选择性的非肽类 δ 阿片 (δ-opioid) 受体激动剂，Ki 为1.78 nM，IC50 为 2.73 nM。SNC80 具有抗伤害性，抗痛觉过敏和抗抑郁样作用，并可用于多种头痛症的研究。
GC49520 (S)-Equol

雌马酚
An estrogen receptor β agonist
GC16372 (Z)-4-Hydroxytamoxifen

4-羟基他莫昔芬; (Z)-4-Hydroxytamoxifen; trans-4-Hydroxytamoxifen; (Z)-Afimoxifene
4-羟基他莫昔芬((Z)-4-Hydroxytamoxifen)是雌激素受体的选择性调节剂(SERM),其影响[3H]oestradiol与雌激素受体结合的IC50值为3.3 nM。
GC62761 1α-Hydroxy-3-epi-vitamin D3 1α-Hydroxy-3-epi-vitamin D3 是 1alpha,25-dihydroxyvitamin D3 的天然代谢物，是甲状旁腺激素 (?PTH?) 分泌的有效抑制剂
GC91226 10-Chloroestra-1,4-diene-3,17-dione

10-chloro-1,4-Estradiene

一种雌激素受体α激动剂
GC40528 11α-hydroxy Testosterone A CYP3A metabolite of testosterone
GC48787 11β-Hydroxyetiocholanolone

11Β-羟基本胆烷醇酮
A metabolite of hydrocortisone