CRTH2

CRTH2(在 T-Helper 2 型细胞上表达的趋化受体同源分子)

CRTh2 (chemoattractant receptor homologous molecule expressed on T-Helper type 2 cells ) is a G-protein coupled receptor for prostaglandin D2. Activation of CRTh2 increases the chemotaxis of Th2 cells/eosinophils/basophil, as well as eosinophil degranulation and Th2 cells cytokine release.

CRTH2 相关产品(2)

  • GC12434 structure
    GC12434AZD1981
    CAS: 802904-66-1
    纯度: >99.50%

    A DP 2 /CRTH 2 receptor antagonist

  • GC13196 structure
    GC13196NVP-QAV680
    CAS: 872365-16-7

    potent and selective CRTh2 receptor antagonist