RAAS(肾素-血管紧张素-醛固酮系统)

RAAS (renin-angiotensin-aldosterone system) is a hormonal signaling cascade that regulates blood pressure, systemic vascular resistance, sodium balance, fluid volume and tissue perfusion etc. It is associated with hypertension, kidney failure and congestive heart failure etc.

Products for RAAS

Cat.No. 产品名称 Information
GC15023 Telmisattan
替米沙坦; BIBR 277
Selective angiotensin II receptor antagonist
GC15736 Rosuvastatin Calcium
瑞舒伐他汀钙; Rosuvastatin hemicalcium; ZD 4522 Calcium
Rosuvastatin Calcium是一种竞争性HMG-CoA还原酶抑制剂，IC₅₀值为11nM。
GC13078 Imidapril HCl
盐酸咪达普利; TA-6366
A prodrug form of imidaprilat
GC15166 Perindopril Erbumine
培哚普利叔丁胺; Perindopril tert-butylamine salt; S-9490 erbumine
An orally active ACE inhibitor
GC16978 Candesartan
坎地沙坦; CV 11974
Candesartan是一种口服血管紧张素II 1型受体（AT1R）阻断剂，IC₅₀值为0.26nM。
GC10257 Losartan Potassium (DuP 753)
氯沙坦钾; DuP-753 potassium
Losartan Potassium (DuP 753)是一种血管紧张素II受体拮抗剂（IC₅₀=20nM）。
GC16223 Captopril
卡托普利; SQ 14225
Captopril是一种具有口服活性的血管紧张素转化酶（ACE）抑制剂，IC₅₀值为0.025μM。