GlpBio

Androgen Receptor

Androgen Receptor(雄激素受体)

AR (androgen receptor) is a member of steroid hormone receptor and ligand-activated transcription factor. It plays a crucial role in prostate cellular proliferation and male sexual differentiation.

Androgen Receptor 相关产品(148)

  • GC13362 structure
    GC13362TOK-001
    CAS: 851983-85-2
    纯度: >99.50%

    A CYP17 inhibitor

  • GC13971 structure
    GC13971Cyproterone Acetate
    CAS: 427-51-0
    纯度: >99.50% / >98.00%

    An androgen receptor antagonist

  • GC10372 structure
    GC10372AZD3514
    CAS: 1240299-33-5
    纯度: >99.00%

    A SARD

  • GC10547 structure
    GC10547ASC-J9
    CAS: 52328-98-0
    纯度: >98.00%

    A selective enhancer of AR degradation

  • GC10567 structure
    GC10567TCPOBOP
    CAS: 76150-91-9
    纯度: >98.00%

    TCPOBOP是一种构成性雄酮受体（CAR）激动剂（EC 50 =0.05μM），能够小鼠诱导肝细胞增殖和肝肿大，但不会造成肝损伤。

  • GC10618 structure
    GC10618Fluoxymesterone
    CAS: 76-43-7

    An Analytical Reference Standard

  • GC10785 structure
    GC10785Danazol
    CAS: 17230-88-5
    纯度: >99.50% / >98.00%

    An androgen receptor agonist

  • GC11070 structure
    GC11070Dehydroepiandrosterone (DHEA)
    CAS: 53-43-0
    纯度: >99.00%

    脱氢表雄酮 (DHEA) 及其硫酸酯 DHEAS 共同代表了人体内最丰富的类固醇激素。

  • GC11386 structure
    GC11386ODM-201
    CAS: 1297538-32-9
    纯度: >99.00%

    ODM-201是一种强效的雄激素受体拮抗剂，K i 值为11nM，IC 50 值为26nM。

  • GC11837 structure
    GC11837MI-136
    CAS: 1628316-74-4
    纯度: >98.50%

    A menin-MLL inhibitor

  • GC11957 structure
    GC11957RD162
    CAS: 915087-27-3

    A second-generation androgen receptor antagonist

  • GC12271 structure
    GC12271Bicalutamide
    CAS: 90357-06-5
    纯度: >98.00%

    Bicalutamide是一种非甾体抗雄激素药物，可通过选择性和竞争性地阻断雄激素与雄激素受体（AR）的结合，在外周组织中发挥抗雄激素作用。

  • GC12385 structure
    GC12385MDV3100 (Enzalutamide)
    CAS: 915087-33-1
    纯度: >99.50%

    MDV3100(enzalutamide) 是第二代 AR 拮抗剂，在 LNCaP 前列腺细胞中的 IC50 为 36nM。

  • GC12445 structure
    GC12445TFM-4AS-1
    CAS: 188589-61-9

    androgen receptor modulator

  • GC12791 structure
    GC127913,3'-Diindolylmethane
    CAS: 1968-05-4
    纯度: >98.00%

    A phytochemical with antiradiation and chemopreventative effects

  • GC12933 structure
    GC12933RU 58841
    CAS: 154992-24-2
    纯度: >99.50%

    A non-steroidal antiandrogen

  • GC12938 structure
    GC12938PF 998425
    CAS: 1076225-27-8
    纯度: >98.00%

    A non-steroidal androgen receptor antagonist

  • GC12974 structure
    GC12974Medroxyprogesterone acetate
    CAS: 71-58-9
    纯度: >99.50%

    Medroxyprogesterone acetate（MPA）是一种人工合成的孕激素。

  • GC13685 structure
    GC13685Andarine
    CAS: 401900-40-1
    纯度: >99.50%

    A selective androgen receptor modulator

  • GC14221 structure
    GC14221HE-3235
    CAS: 183387-50-0

    Androgen receptor antagonist

  • GC14560 structure
    GC14560Cl-4AS-1
    CAS: 188589-66-4

    Cl-4AS-1 是一种有效的甾体雄激素受体 (AR) 激动剂 (IC50 = 12 nM)，也是 5α-还原酶 I 型和 II 型的抑制剂（IC50 分别为 6 和 10 nM）。

  • GC15774 structure
    GC157745α-dihydro-11-keto Testosterone
    CAS: 32694-37-4
    纯度: >98.00%

    An Analytical Reference Standard

  • GC16631 structure
    GC16631EPI-001
    CAS: 227947-06-0
    纯度: >98.00%

    An androgen receptor antagonist

  • GC16649 structure
    GC16649TAK-700 (Orteronel)
    CAS: 426219-18-3

    A non-steroidal inhibitor of the 17,20-lyase activity of CYP17A1