RU 58841

目录号: GC12933纯度: >99.50%同义词: RU58841; RU-58841
A non-steroidal antiandrogen

RU 58841
Cas No.: 154992-24-2
规格价格库存数量操作
1mg¥140.00现货
1
5mg¥294.00现货
1
10mg¥434.00现货
1
25mg¥728.00现货
1
50mg¥1,162.00现货
1
100mg¥1,855.00现货
1
10mM (in 1mL DMSO)¥239.00现货
1

文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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    Cell
    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

产品描述 Description

RU 58841 (PSK-3841) is a specific androgen receptor antagonist or anti-androgen. RU 58841 (PSK-3841) has a dramatic effect on hair regrowth.

References:
[1]. A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice By De Brouwer, B.; Tetelin, C.; Leroy, T.; Bonfils, A.; Van Neste, D. .From British Journal of Dermatology (1997), 137(5), 699-702.
[2]. Münster U, Nakamura C, Haberland A, Jores K, Mehnert W, Rummel S, Schaller M, Korting HC, Zouboulis ChC, Blume-Peytavi U, Sch fer-Korting M.RU 58841-myristate--prodrug development for topical treatment of acne and androgenetic alopecia.Pharmazie. 2005 Jan;60(1):8-12.
[3]. Battmann T, Bonfils A, Branche C, Humbert J, Goubet F, Teutsch G, Philibert D.RU 58841, a new specific topical antiandrogen: a candidate of choice for the treatment of acne, androgenetic alopecia and hirsutism.J Steroid Biochem Mol Biol. 1994 Jan;48(1):55-60.
[4]. Blaschke T, Kankate L, Kramer KD.Structure and dynamics of drug-carrier systems as studied by parelectric spectroscopy.Adv Drug Deliv Rev. 2007 Jul 10;59(6):403-10. Epub 2007 May 3.
[5]. Matias JR, Gaillard M.Local inhibition of sebaceous gland growth by topically applied RU 58841.Ann N Y Acad Sci. 1995 Jun 12;761:56-65.

产品文档 Product Documents

Purity:>99.50%

化学性质Chemical Properties

CAS 号
154992-24-2
同义词
RU58841; RU-58841
化学名
4-[3-(4-hydroxybutyl)-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile
SMILES
CC1(C(=O)N(C(=O)N1CCCCO)C2=CC(=C(C=C2)C#N)C(F)(F)F)C
分子式
C17H18F3N3O3
分子量
369.35 g/mol
溶解性
≥ 36.9 mg/mL in DMSO, ≥ 87.6 mg/mL in EtOH
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至 37°C,然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备 RT,或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol