GlpBio

Androgen Receptor

Androgen Receptor(雄激素受体)

AR (androgen receptor) is a member of steroid hormone receptor and ligand-activated transcription factor. It plays a crucial role in prostate cellular proliferation and male sexual differentiation.

Androgen Receptor 相关产品(148)

  • GC33224 structure
    GC33224Proxalutamide (GT0918)
    CAS: 1398046-21-3
    纯度: >98.50% / >98.00%

    Proxalutamide (GT0918)是一种新型的、具有口服活性的雄激素受体（AR）拮抗剂，Proxalutamide可下调TMPRSS2和ACE2的表达来抑制病毒进入宿主细胞，同时通过激活Nrf2通路以减少炎症。

  • GC34005 structure
    GC34005Dehydroisoandrosterone 3-acetate (Dehydroepiandrosterone 3-acetate)
    CAS: 853-23-6
    纯度: >98.00%

    Dehydroepiandrosterone 3-acetate 是一种睾酮/雌激素前体和已知的脊椎动物攻击性调节剂。

  • GC34887 structure
    GC34887Androstanolone acetate
    CAS: 1164-91-6
    纯度: >98.00%

    Androstanoloneacetate是一种雄激素配体，靶向作用于雄激素受体α(AR)。Androstanoloneacetate通过连接桥与cIAP1配体Bestatin结合从而形成PROTAC分子。

  • GC35069 structure
    GC350692,2,5,7,8-Pentamethyl-6-Chromanol
    CAS: 950-99-2
    纯度: >98.50%

    2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) 是维生素 E (α-tocopherol) 的抗氧化部分。2,2,5,7,8-Pentamethyl-6-Chromanol 具有有效的雄激素受体 (androgen receptor) 信号调节和抗前列腺癌细胞系的抗癌活性。

  • GC35534 structure
    GC35534BMS-564929
    CAS: 627530-84-1
    纯度: >99.00%

    BMS-564929 是一种 雄激素受体 (AR) 激动剂，结合到雄激素受体，Ki 为 2.11±0.16 nM。

  • GC35541 structure
    GC35541Boldenone Undecylenate
    CAS: 13103-34-9

    An Analytical Reference Standard

  • GC36344 structure
    GC36344Isosilybin B
    CAS: 142796-22-3

    Isosilybin B，一种从 silymarin 中分离的黄酮木脂素，具有抗前列腺癌 (PCA) 活性，抑制癌细胞增殖，诱导 G1 期阻滞和凋亡。Isosilybin B 引起雄激素受体降解。

  • GC36621 structure
    GC36621MK-0773
    CAS: 606101-58-0
    纯度: >98.00%

    MK-0773 是一种选择性雄激素受体调节剂 (selective androgen receptor modulators)，与 AR 结合，IC50 值为 6.6 nM。

  • GC36820 structure
    GC36820Ostarine
    CAS: 841205-47-8

    Ostarine (GTx-024, MK-2866, Enobosarm) is a selective androgen receptor modulator (SARM) with Ki of 3.8 nM, and is tissue-selective for anabolic organs. Phase 3.

  • GC36981 structure
    GC36981PROTAC AR Degrader-4
    CAS: 1351169-31-7

    PROTAC AR Degrader-4 包含 cIAP1 配体结合基团，linker 和雄激素受体 (AR) 配体结合基团。基于 cIAP1 的降解剂也被称为 SNIPER。

  • GC37687 structure
    GC37687Stanolone benzoate
    CAS: 1057-07-4
    纯度: >99.50%

    Stanolone benzoate (Androstanolone benzoate) 是一种合成的雄激素和合成代谢类固醇。

  • GC39451 structure
    GC39451Testosterone (propionate)
    CAS: 57-85-2
    纯度: >99.50% / >98.00%

    An Analytical Reference Standard

  • GC40528 structure
    GC4052811α-hydroxy Testosterone
    CAS: 3066-12-4
    纯度: >97.00%

    A CYP3A metabolite of testosterone

  • GC41153 structure
    GC41153Tibolone
    CAS: 5630-53-5
    纯度: >98.00%

    Tibolone是一种合成类固醇，具有弱雌激素、孕激素及雄激素活性。

  • GC41300 structure
    GC4130017β-hydroxy Exemestane
    CAS: 122370-91-6
    纯度: >98.00%

    An active metabolite of exemestane

  • GC44363 structure
    GC44363Neoaureothin
    CAS: 59795-94-7
    纯度: >98.00%

    A bacterial metabolite

  • GC44405 structure
    GC44405Nilutamide
    CAS: 63612-50-0
    纯度: >98.00%

    A non-steroidal androgen receptor antagonist

  • GC44527 structure
    GC44527p,p'-DDE
    CAS: 72-55-9
    纯度: >99.50%

    A metabolite and degradation product of the pesticide DDT

  • GC44686 structure
    GC44686Prochloraz
    CAS: 67747-09-5
    纯度: >98.00%

    An imidazole antifungal

  • GC44861 structure
    GC44861S-23
    CAS: 1010396-29-8
    纯度: >99.50%

    A selective androgen receptor modulator

  • GC45239 structure
    GC45239δ4-Abiraterone
    CAS: 154229-21-7
    纯度: >99.00%

    An active metabolite of abiraterone

  • GC45530 structure
    GC45530Norgestrel-d6
    CAS: 2376035-98-0
    纯度: >99.00%

    An internal standard for the quantification of norgestrel

  • GC45935 structure
    GC45935Testosterone
    CAS: 58-22-0
    纯度: >98.00%

    An Analytical Reference Standard

  • GC46456 structure
    GC4645616α-Hydroxyetiocholanolone
    CAS: 14167-50-1
    纯度: >95.00%

    A metabolite of 16α-DHEA and androstenedione