p,p'-DDE is a metabolite and degradation product of the organochlorine pesticide DDT. It accumulates in smallmouth buffalo, channel catfish, and largemouth bass as well as sediment in the Huntsville Spring Branch-Indian Creek tributary system surrounding a DDT manufacturing plant where it is considered a persistent organic pollutant (POP). p,p'-DDE inhibits estrogen binding to rainbow trout estrogen receptors (rtERs) with an IC50 value of 8 µM. It induces concentration-dependent secretion of estradiol by granulosa and theca cell co-cultures isolated from porcine ovarian follicles. p,p'-DDE (50-100 µM) also decreases ATP levels, the proportion of sperm with high mitochondrial membrane potential, and motility of human sperm in vitro.
p,p'-DDE
目录号: GC44527纯度: >99.50%同义词: 2，2-双（4-氯苯基）-1，1-二氯乙烯,4,4'-DDE; p,p'-Dichlorodiphenyldichloroethylene
A metabolite and degradation product of the pesticide DDT
Cas No.: 72-55-9
| 规格 | 价格 | 库存 | 数量 | 操作 |
|---|---|---|---|---|
| 100mg | ¥1,186.00 | 现货 | 1 | |
| 250mg | ¥990.00 | 现货 | 1 | |
| 500mg | ¥1,485.00 | 现货 | 1 | |
| 10mM (in 1mL DMSO) | ¥762.00 | 现货 | 1 |
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Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
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产品描述 Description
产品文档 Product Documents
Purity:>99.50%Appearance:A solid
化学性质Chemical Properties
CAS 号
72-55-9
同义词
2，2-双（4-氯苯基）-1，1-二氯乙烯,4,4'-DDE; p,p'-Dichlorodiphenyldichloroethylene
SMILES
ClC1=CC=C(/C(C2=CC=C(Cl)C=C2)=C(Cl)\Cl)C=C1
分子式
C14H8Cl4
分子量
318 g/mol
溶解性
DMSO : 100 mg/mL (314.44 mM; Need ultrasonic)
保存条件
4°C, protect from light
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。
计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度
g/mol