Drug Metabolite
Drug Metabolite(药物代谢物)
Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.
Drug Metabolite 相关产品(498)
- GC10822Clozapine N-oxide (CNO)CAS: 34233-69-7纯度: >98.00%
Clozapine N-oxide（CNO）是一种强效的多巴胺拮抗剂，也是一种选择性肌动蛋白M4受体（EC50=11 nM）激动剂。
- GC15168Urolithin ACAS: 1143-70-0纯度: >98.00%
Urolithin A是由鞣花酸和鞣花单宁代谢产生的一种活性成分，可作为酪氨酸酶（IC 50 值为71.44±10.07µmol/L）和单胺氧化酶A（IC 50 值为29.41±9.01µmol/L）的强效抑制剂。
- GC185394-Hydroxyretinoic acid (4-HRA)CAS: 66592-72-1纯度: >98.00%
4-Hydroxyretinoic acid (4-HRA)是一种天然存在的，由全反式视黄酸（ATRA）经细胞色素P450酶代谢生成的主要代谢产物。
- GC18569Propofol β-D-GlucuronideCAS: 114991-26-3纯度: >98.00%
Propofol β-D-Glucuronide是丙泊酚的代谢产物，被广泛用作鉴定动物体内丙泊酚代谢状态的标志物。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC10822 | Clozapine N-oxide (CNO) | 34233-69-7 | >98.00% | |
Clozapine N-oxide（CNO）是一种强效的多巴胺拮抗剂，也是一种选择性肌动蛋白M4受体（EC50=11 nM）激动剂。 | ||||
| GC11155 | Omeprazole sulfone | 88546-55-8 | - | |
The major metabolite of omeprazole | ||||
| GC11989 | Nortriptyline (hydrochloride) | 894-71-3 | >99.50% | |
A tricyclic antidepressant | ||||
| GC12685 | Ercalcitriol | 60133-18-8 | >99.00% | |
A potent agonist of the vitamin D receptor | ||||
| GC14762 | Palifosfamide | 31645-39-3 | - | |
An active metabolite of ifosfamide | ||||
| GC14780 | Oseltamivir acid | 187227-45-8 | >98.50% / >98.00% | |
A neuraminidase inhibitor and antiviral | ||||
| GC15168 | Urolithin A | 1143-70-0 | >98.00% | |
Urolithin A是由鞣花酸和鞣花单宁代谢产生的一种活性成分，可作为酪氨酸酶（IC 50 值为71.44±10.07µmol/L）和单胺氧化酶A（IC 50 值为29.41±9.01µmol/L）的强效抑制剂。 | ||||
| GC16292 | Equol | 94105-90-5 | >98.00% | |
An estrogen receptor agonist | ||||
| GC16333 | Cycloguanil (hydrochloride) | 152-53-4 | >99.50% | |
The active metabolite of proguanil | ||||
| GC16553 | N-Desmethylclozapine | 6104-71-8 | >99.50% | |
An active metabolite of clozapine | ||||
| GC18194 | 4-Epidoxycycline | 6543-77-7 | - | |
A metabolite of doxycycline | ||||
| GC18219 | 6-hydroxy Warfarin | 17834-02-5 | >98.00% | |
A phase I metabolite of (+)-warfarin | ||||
| GC18335 | 6β-hydroxy Dexamethasone | 55879-47-5 | - | |
A metabolite of dexamethasone | ||||
| GC18417 | 4-hydroxy Xylazine | 145356-32-7 | >98.00% / >97.50% | |
A xylazine metabolite | ||||
| GC18425 | 4-hydroxy Atorvastatin lactone | 163217-70-7 | - | |
A metabolite of atorvastatin | ||||
| GC18439 | Doxorubicinone | 24385-10-2 | >95.00% | |
A metabolite of doxorubicin | ||||
| GC18455 | Digoxigenin Monodigitoxoside | 5352-63-6 | - | |
A Na + /K + -ATPase inhibitor | ||||
| GC18466 | 5,6-epoxy-13-cis Retinoic Acid | 81444-57-7 | - | |
A metabolite of 13-cis retinoic acid | ||||
| GC18527 | 4'-hydroxy Flurbiprofen | 52807-12-2 | - | |
A major active metabolite of flurbiprofen | ||||
| GC18539 | 4-Hydroxyretinoic acid (4-HRA) | 66592-72-1 | >98.00% | |
4-Hydroxyretinoic acid (4-HRA)是一种天然存在的，由全反式视黄酸（ATRA）经细胞色素P450酶代谢生成的主要代谢产物。 | ||||
| GC18542 | 5,6-dihydro-5-Fluorouracil | 696-06-0 | >95.00% | |
A metabolite of 5-FU | ||||
| GC18569 | Propofol β-D-Glucuronide | 114991-26-3 | >98.00% | |
Propofol β-D-Glucuronide是丙泊酚的代谢产物，被广泛用作鉴定动物体内丙泊酚代谢状态的标志物。 | ||||
| GC18582 | 5'-hydroxy Meloxicam | 130262-92-9 | - | |
A metabolite of meloxicam | ||||
| GC18596 | (±)-2-propyl-4-Pentenoic Acid | 1575-72-0 | >98.00% | |
A metabolite of valproic acid | ||||