Drug Metabolite(药物代谢物)

Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Products for Drug Metabolite

Cat.No. 产品名称 Information
GC49294 1-(4-Chlorobenzhydryl)piperazine
1-(4-氯二苯甲基)哌嗪
An inactive metabolite of meclizine and chlorcyclizine
GC49291 rac-N-desmethyl Ivabradine-d6 (hydrochloride) An internal standard for the quantification of N-desmethyl ivabradine
GC49289 Dolutegravir O-β-D-Glucuronide
Dolutegravir Glucuronide, DTG Glucuronide
A metabolite of dolutegravir
GC49288 Dolutegravir M1
多替拉韦杂质
A metabolite of dolutegravir
GC49282 Hydroxy Lenalidomide
羟基来那度胺
A metabolite of lenalidomide
GC49256 N-acetyl Lenalidomide
N-乙酰来那度胺
A metabolite of lenalidomide
GC49252 4’-hydroxy Trazodone A metabolite of trazodone
GC49250 Hydroxydehydro Nifedipine Carboxylate
羟基去氢硝苯羧酸酯
A metabolite of nifedipine
GC49241 Methyl Diethyldithiocarbamate
S-甲基N,N二乙基二硫代氨基甲酸
An active metabolite of disulfiram
GC49235 6-Methylmercaptopurine
6-甲巯基嘌呤
A metabolite of 6-mercaptopurine
GC49219 N-desmethyl Eletriptan
N-去甲基依曲普坦
A metabolite of eletriptan
GC49218 Imidafenacin Metabolite M4
咪达那新相关物质2(N-(3氨基甲酰基3,3-DIPHENYLPROPYL)乙二酰二胺)
A metabolite of imidafenacin
GC49217 Trifluoperazine N-Glucuronide
三氟拉嗪N-Β-D-葡糖苷酸,UGT1A4
A metabolite of trifluoperazine
GC49216 ADL 08-0011 (hydrochloride)
阿维莫潘代谢物(ADL08-0011)盐酸盐
An active metabolite of alvimopan
GC49213 trans-hydroxy Glimepiride
反式羟基格列美脲
An active metabolite of glimepiride
GC49212 trans-carboxy Glimepiride
格列美脲杂质8
A metabolite of glimepiride
GC49211 O-desmethyl Brinzolamide (hydrochloride) An active metabolite of brinzolamide
GC49210 N-desethyl Brinzolamide (oxalate)
AL 8520
An active metabolite of brinzolamide
GC49203 rac-Desethyl Oxybutynin (hydrochloride)
(R,S)-DEOB
An active metabolite of oxybutynin
GC49202 Desmethyl Mirtazapine (hydrochloride)
盐酸去甲基米氮平
A metabolite of mirtazapine
GC49189 (E/Z)-4-hydroxy Tamoxifen-d5
Afimoxifene-d5, 4-OHT-d5
An internal standard for the quantification of (E/Z)-4-hydroxy tamoxifen
GC49186 O-Demethyl Apremilast
阿普斯特杂质
An active metabolite of apremilast
GC49185 Mirtazapine N-oxide
米氮平杂质A
A metabolite of mirtazapine
GC49184 Palonosetron N-oxide
帕洛诺司琼N氧化物
A metabolite of palonosetron
GC49179 (S)-O-Desmethyl Naproxen
萘普生杂质A
A metabolite of (S)-naproxen
GC49174 Desmethyl Bosentan
波生坦O-去甲基杂质
An active metabolite of bosentan
GC49173 N-Despropyl Ropinirole
1,3-二氢-4-[2-(丙基氨基)乙基]-2H-吲哚-2-酮
An active metabolite of ropinirole
GC49159 2-(1-Piperazinyl)pyrimidine
1-(2-嘧啶基)哌嗪
An α₂-AR antagonist and active metabolite of azapirones
GC49157 rac-5-carboxy Tolterodine
5-羧基托特罗定
An inactive metabolite of tolterodine
GC49156 Etodolac Acyl Glucuronide
依托度酸酰基-Β-D葡糖苷酸
A phase II metabolite of etodolac
GC49152 Celecoxib Carboxylic Acid
羧酸塞来昔布
An inactive metabolite of celecoxib
GC49147 Carboxyphosphamide
CPCOOH, NSC 145124
An inactive metabolite of cyclophosphamide
GC49133 N-hydroxy Riluzole
N-羟基利鲁唑
A metabolite of riluzole
GC49131 Dehydro Warfarin
去羟基华法林
A metabolite of (±)-warfarin
GC49130 Hydroxy Celecoxib
羟甲基塞来昔布
An inactive metabolite of celecoxib
GC49127 4-oxo Cyclophosphamide
4-keto CP, 4-keto Cyclophosphamide, NSC 139488, 4-oxo CP
An inactive metabolite of cyclophosphamide
GC49119 5-hydroxy Flunixin
5-羟基氟尼辛
A metabolite of flunixin
GC49118 10-hydroxy Warfarin
10-羟基华法林(非对映体的混合物)

A metabolite of (R)-warfarin
GC49115 Desacetylcefotaxime (potassium salt)
des-CTX
An active metabolite of cefotaxime
GC49111 Carbamazepine 10,11-epoxide
卡马西平10,11-环氧化物
An active metabolite of carbamazepine
GC49100 Desmethyl Ofloxacin (hydrochloride) A metabolite of ofloxacin
GC49051 7-hydroxy Methotrexate
7-羟基甲氨蝶呤
A metabolite of methotrexate
GC49017 8-hydroxy Amoxapine A metabolite of amoxapine
GC48979 Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate)
E217G, βEstradiol 17(βDGlucuronide), 17βEstradiol 17(βDGlucuronide), 17βOestradiol 17(βDGlucuronide)
A substrate of multidrug resistance protein 2
GC62481 AST5902 trimesylate AST5902 is the principal metabolite of alflutinib both in vitro and in vivo, which exerts remarkable antineoplastic activity similar to alflutinib. AST5902 exhibits much weak CYP3A4 induction potential compared to alflutinib.
GC62278 FTISADTSK acetate FTISADTSK acetate 是一种内源性稳定的曲妥珠单抗信号肽，由SRM监测得到。
GC62152 Homovanillyl alcohol
高香草醇
Homovanillyl alcohol 是羟基酪醇的生物代谢产物。Hydroxytyrosol 是原始橄榄油 (VOO) 和葡萄酒中存在的一种酚类化合物。Homovanillyl alcohol 可保护红细胞 (RBCs) 免受氧化损伤，并对心血管疾病具有保护作用。
GC62033 3α-Hydroxy pravastatin sodium
3Α-羟基普伐他汀钠
A metabolite of pravastatin
GC61864 DL-Laudanosine DL-Laudanosine 是 Atracurium 和 Cisatracurium 的代谢物，可透过血脑屏障，引起兴奋和癫痫发作。
GC61813 O-Desmethyl Mebeverine alcohol hydrochloride
Mebeverine metabolite O-desmethyl Mebeverine alcohol hydrochloride
O-DesmethylMebeverinealcoholhydrochloride是Mebeverine的代谢物，Mebeverine是一种有效的α1受体(α1repector)抑制剂，用作消化道的一种解痉药。