Megestrol, a synthetic progestin, is approved for the treatment of anorexia, cachexia, or an unexplained significant weight loss in patients with an acquired immunodeficiency syndrome diagnosis. Megestrol acetate (Megace) is one of the first progestational agents to be evaluated for use in the hormonal therapy of advanced breast cancer.
[1] Jose M Garcia, Tatyana A Shamliyan. Am J Med. 2018 Jun;131(6):623-629.e1. [2] S M Sedlacek. Semin Oncol. 1988 Apr;15(2 Suppl 1):3-13.
















