GlpBio

Androgen Receptor

Androgen Receptor(雄激素受体)

AR (androgen receptor) is a member of steroid hormone receptor and ligand-activated transcription factor. It plays a crucial role in prostate cellular proliferation and male sexual differentiation.

Androgen Receptor 相关产品(148)

  • GC16840 structure
    GC16840ARN-509
    CAS: 956104-40-8
    纯度: >99.50%

    ARN-509是一种合成的双芳基硫代乙内酰脲化合物，抑制雄激素受体（AR），IC 50 值为16nM。

  • GC17160 structure
    GC171602-hydroxy Flutamide
    CAS: 52806-53-8

    An active metabolite of the antiandrogen flutamide

  • GC17491 structure
    GC17491CITCO
    CAS: 338404-52-7
    纯度: >99.50%

    An agonist of human CAR

  • GC17557 structure
    GC1755717 alpha-propionate
    CAS: 19608-29-8
    纯度: >98.50%

    A peripherally selective androgen receptor antagonist

  • GC17679 structure
    GC17679GSK2881078
    CAS: 1539314-06-1
    纯度: >99.00%

    A selective androgen receptor modulator

  • GC18496 structure
    GC18496Leelamine (hydrochloride)
    CAS: 16496-99-4

    An inhibitor of pyruvate dehydrogenase kinase

  • GC19305 structure
    GC19305RAD140
    CAS: 1182367-47-0
    纯度: >99.00%

    An androgen receptor modulator

  • GC19458 structure
    GC194586β-hydroxy Testosterone
    CAS: 62-99-7
    纯度: >97.00%

    CYP3A metabolite of testosterone

  • GC26431 structure
    GC26431Pentacosafluorotridecanoic Acid
    CAS: 72629-94-8
    纯度: >97.00%

    Perfluorotridecanoic Acid (Perfluorinated Compound (PFC)) is a perfluorinated alkyl acid (PFAA) and a possible organic pollutant.

  • GC30086 structure
    GC30086GLPG0492
    CAS: 1215085-92-9
    纯度: >99.50%

    A selective androgen receptor modulator

  • GC30101 structure
    GC30101GLPG0492 R enantiomer
    CAS: 1215085-93-0
    纯度: >99.50%

    GLPG0492Renantiomer是GLPG0492的R型对映体，GLPG0492是新型选择性SARM

  • GC30710 structure
    GC30710(R)-UT-155
    CAS: 2031161-54-1
    纯度: >98.00%

    (R)-UT-155(compound11)是一种选择性的、雄激素受体降解物(SARD)配体。活性低于S型异构体。

  • GC31254 structure
    GC31254Androst-4-ene-3,17-diol, dipropanoate, (3β,17β)- (Androst-4-ene-3β,17β-diol, dipropionate)
    CAS: 56699-31-1

    Androst-4-ene-3,17-diol,dipropanoate,(3β,17β)-是睾酮代谢物4-雄烯二醇的二丙酸酯。

  • GC31380 structure
    GC31380LY2452473
    CAS: 1029692-15-6
    纯度: >98.00%

    LY2452473是一种选择性雄激素受体（AR）调节剂（SARM）。

  • GC31441 structure
    GC31441DJ-V-159
    CAS: 2253744-53-3
    纯度: >99.50%

    DJ-V-159 is an agonist for G protein-coupled receptor family C group 6 member A (GPRC6A).

  • GC31442 structure
    GC31442YK11
    CAS: 1370003-76-1
    纯度: >98.00%

    A partial agonist of the androgen receptor

  • GC31577 structure
    GC31577Bifluranol (BX341)
    CAS: 34633-34-6
    纯度: >98.50%

    Bifluranol (BX341) (BX341) 是一种抗雄激素。

  • GC31738 structure
    GC31738ACP-105
    CAS: 899821-23-9
    纯度: >99.00%

    ACP-105 is an orally available and potent selective androgen receptor modulator (SARM) with pEC50 of 9.0 and 9.4 for AR wild type and AR mutation T877A, respectively.

  • GC31742 structure
    GC31742Ailanthone (δ13-Dehydrochaparrinone)
    CAS: 981-15-7
    纯度: >99.50% / >98.00%

    Ailanthone (δ13-Dehydrochaparrinone)是一种源自传统中药植物臭椿（ Ailanthus altissima ）的苦木素类化合物，是全长雄激素受体（AR）（IC 50 =69nM）及其组成型活性截短剪接变体（AR-Vs）（IC 50 =309nM）的强效抑制剂。

  • GC32402 structure
    GC32402ORM-15341
    CAS: 1297537-33-7
    纯度: >98.50%

    ORM-15341 is a potent and full antagonist for human AR (hAR) with IC50 value of 38 nM and the inhibition constant (Ki) value of 8?nM.

  • GC32403 structure
    GC32403LGD-3303
    CAS: 917891-35-1
    纯度: >98.00%

    LGD-3303是一种口服的非甾体选择性雄激素受体调节剂（SARM），与雄激素受体具有高亲和力（K i =0.9nM）。

  • GC32408 structure
    GC32408LGD-4033 (Ligandrol)
    CAS: 1165910-22-4

    An Analytical Reference Standard

  • GC32907 structure
    GC32907N-desmethyl Enzalutamide (N-desmethyl MDV 3100)
    CAS: 1242137-16-1
    纯度: >99.00%

    N-desMethyl EnzalutaMide (N-desmethyl MDV 3100) is the active metabolite of Enzalutamide, which is an oral androgen receptor inhibitor for treatment of castration-resistant prostate cancer.

  • GC32908 structure
    GC32908UT-155
    CAS: 2031161-35-8
    纯度: >99.50%

    UT-155是一种选择性的、有效的雄激素受体(AR)拮抗剂，与AR-LBD结合的Ki值为267nM。