Endocrinology and Hormones
Endocrinology and Hormones(内分泌和激素)
Endocrinology and Hormones
The endocrine system is an information signaling system that coordinates most bodily functions. It senses environmental changes and secretes corresponding hormones to coordinate metabolism, maintain homeostasis, and regulate growth and development.read more
Endocrinology and Hormones 相关产品(940)
- GC10037BexaroteneCAS: 153559-49-0纯度: >99.50%
Bexarotene是一种选择性视黄醇X受体（RXR）激动剂，对RXRα、RXRβ和RXRγ的EC 50 值分别为0.028µM、0.025µM和0.020µM。
- GC10413Thyroid Hormone Receptor Antagonist (1-850)CAS: 251310-57-3
Blocks T3 binding to the thyroid hormone receptor
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GA20972 | Boc-D-Leu-OSu | 60111-76-4 | - | |
An amino acid-containing building block | ||||
| GA21407 | Dynorphin A (1-8) | 75790-53-3 | - | |
Dynorphin A (1-8) 是在胎盘组织提取物中发现的主要阿片肽。 | ||||
| GA23395 | pTH (1-34) (rat) | 98614-76-7 | >95.00% | |
pTH (1-34)（大鼠）是一种甲状旁腺激素。 | ||||
| GC10002 | Coumestrol | 479-13-0 | >98.00% | |
A naturally-occurring phytoestrogen | ||||
| GC10012 | Chlorotrianisene | 569-57-3 | >99.00% | |
A synthetic non-steroidal estrogen | ||||
| GC10037 | Bexarotene | 153559-49-0 | >99.50% | |
Bexarotene是一种选择性视黄醇X受体（RXR）激动剂，对RXRα、RXRβ和RXRγ的EC 50 值分别为0.028µM、0.025µM和0.020µM。 | ||||
| GC10064 | Flurizan | 51543-40-9 | >99.50% | |
A COX-inactive enantiomer of flurbiprofen | ||||
| GC10080 | CD 2314 | 170355-37-0 | - | |
CD 2314 是一种有效的选择性 RARβ 受体激动剂，在 S91 黑色素瘤细胞中的 Kd 为 195 nM。 | ||||
| GC10180 | Cyclofenil | 2624-43-3 | - | |
An Analytical Reference Standard | ||||
| GC10212 | MM 11253 | 345952-44-5 | >98.00% | |
A selective antagonist of RARγ | ||||
| GC10346 | Y 134 | 849662-80-2 | >98.00% | |
Y 134 是一种选择性和口服活性的雌激素受体 (ER) 调节剂 (SERM)，对 ERα 和 ERβ 表现出有效的拮抗剂活性。 Y 134 对 ERα (Ki\u003d0.09 nM) 的选择性比对 ERβ (Ki\u003d11.31 nM) 的选择性高 121.1 倍。 Y 134 抑制雌激素刺激的 ER 阳性人乳腺癌细胞增殖。 | ||||
| GC10372 | AZD3514 | 1240299-33-5 | >99.00% | |
A SARD | ||||
| GC10384 | 3,3',5'-Triiodo-L-thyronine | 5817-39-0 | - | |
A thyroid hormone variant | ||||
| GC10389 | ERB 041 | 524684-52-4 | >98.00% | |
An ERβ agonist | ||||
| GC10413 | Thyroid Hormone Receptor Antagonist (1-850) | 251310-57-3 | - | |
Blocks T3 binding to the thyroid hormone receptor | ||||
| GC10547 | ASC-J9 | 52328-98-0 | >98.00% | |
A selective enhancer of AR degradation | ||||
| GC10558 | GSK 4716 | 101574-65-6 | >98.00% | |
An ERRβ/γ agonist | ||||
| GC10567 | TCPOBOP | 76150-91-9 | >98.00% | |
TCPOBOP是一种构成性雄酮受体（CAR）激动剂（EC 50 =0.05μM），能够小鼠诱导肝细胞增殖和肝肿大，但不会造成肝损伤。 | ||||
| GC10596 | T0901317 | 293754-55-9 | >99.50% | |
T0901317是一种口服活性高选择性LXR激动剂，对LXRα的EC 50 为15nM，并能激活异生物质受体孕烷X受体(PXR)，EC 50 为23nM。 | ||||
| GC10610 | Adapalene | 106685-40-9 | >98.00% | |
An RARβ and RARγ agonist | ||||
| GC10618 | Fluoxymesterone | 76-43-7 | - | |
An Analytical Reference Standard | ||||
| GC10656 | BMS 453 | 166977-43-1 | >98.50% | |
An RARβ agonist, RARα/γ antagonist | ||||
| GC10663 | Dihydrodaidzein | 17238-05-0 | >98.00% | |
An active metabolite of daidzein | ||||
| GC10684 | Zearalanone | 5975-78-0 | >99.50% | |
A mycotoxin with estrogen-like effects | ||||