Aromatase
Aromatase(芳香酶)
Aromatase is an enzyme which belongs to the cytochrome p450 superfamily. It localizes on the endoplasmic reticulum of estrogen producing cell and catalyzes the final step of estrogen biosynthesis, converting androgen to estrogens.
Aromatase 相关产品(12)
- GC11813ExemestaneCAS: 107868-30-4纯度: >99.50%
A third generation, irreversible steroidal aromatase inhibitor
- GC38682FlavanoneCAS: 487-26-3纯度: >98.00%
Flavanones (2,3-Dihydroflavone, 4-Flavanone, 2-Phenyl-4-chromanone, 2-Phenylchroman-4-one) show strong antioxidant and radical scavenging activity, and appear to be associated with a reduced risk of certain chronic diseases, the prevention of some cardiovascular disorders, and certain kinds of cancer. Flavanones also exhibit antiviral, antimicrobial, and anti-inflammatory activities, beneficial effects on capillary fragility, and an ability to inhibit human platelet aggregation, anti-ulcer, and anti-allergenic properties.
- GC63755Exemestane-D2
Exemestane-D2 (FCE 24304-D2) 是 Exemestane 的氘代物。Exemestane (FCE 24304) 是一种选择性，不可逆和具有口服活性的甾体芳香酶 (aromatase) 抑制剂，对人胎盘和大鼠卵巢芳香酶的 IC50 分别为 30 nM 和 40 nM。Exemestane 可用于激素依赖性乳腺癌研究。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC10256 | Anastrozole | 120511-73-1 | >99.50% | |
An aromatase/CYP19A1 inhibitor | ||||
| GC10726 | Letrozole | 112809-51-5 | >99.50% / >98.00% | |
Letrozole（来曲唑; CGS 20267）是一种口服活性非甾体类选择性芳香酶抑制剂，IC 50 为11.5nM。 | ||||
| GC11813 | Exemestane | 107868-30-4 | >99.50% | |
A third generation, irreversible steroidal aromatase inhibitor | ||||
| GC16433 | Aminoglutethimide | 125-84-8 | >98.50% | |
An aromatase inhibitor | ||||
| GC12140 | Endoxifen | 112093-28-4 | - | |
Endoxifen Z-异构体是最重要的他莫昔芬代谢物，负责在表达雌激素受体-α (ERα) 的乳腺癌细胞中引发该药物的抗雌激素作用。 | ||||
| GC12890 | α-Naphthoflavone | 604-59-1 | >99.00% | |
A flavone that modulates xenobiotic metabolism | ||||
| GC18301 | Fadrozole (hydrochloride) | 102676-31-3 | >99.00% | |
A non-steroidal aromatase inhibitor | ||||
| GC19151 | Fadrozole | 102676-47-1 | >99.50% | |
Fadrozole (CGS 16949A)是一种选择性非甾体芳香酶抑制剂，IC 50 值为4.5μM。 | ||||
| GC38682 | Flavanone | 487-26-3 | >98.00% | |
Flavanones (2,3-Dihydroflavone, 4-Flavanone, 2-Phenyl-4-chromanone, 2-Phenylchroman-4-one) show strong antioxidant and radical scavenging activity, and appear to be associated with a reduced risk of certain chronic diseases, the prevention of some cardiovascular disorders, and certain kinds of cancer. Flavanones also exhibit antiviral, antimicrobial, and anti-inflammatory activities, beneficial effects on capillary fragility, and an ability to inhibit human platelet aggregation, anti-ulcer, and anti-allergenic properties. | ||||
| GC63755 | Exemestane-D2 | - | - | |
Exemestane-D2 (FCE 24304-D2) 是 Exemestane 的氘代物。Exemestane (FCE 24304) 是一种选择性，不可逆和具有口服活性的甾体芳香酶 (aromatase) 抑制剂，对人胎盘和大鼠卵巢芳香酶的 IC50 分别为 30 nM 和 40 nM。Exemestane 可用于激素依赖性乳腺癌研究。 | ||||
| GN10457 | Oleuropein | 32619-42-4 | >98.00% | |
Oleuropein是橄榄树中的主要酚类化合物，具有强效的抗氧化和抗炎特性。 | ||||
| GC12815 | Formestane | 566-48-3 | - | |
An Analytical Reference Standard | ||||