Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for Neuroscience

Cat.No. 产品名称 Information
GC42417 4-hydroxy-3-Methoxyphenylglycol (piperazine salt)

4-羟基-3-甲氧基苯基乙二醇半哌嗪盐
A norepinephrine metabolite
GC60517 4-Hydroxyatomoxetine

4'-羟基托莫西汀
A metabolite of atomoxetine
GC60519 4-Hydroxyderricin

4-羟基德里辛
4-Hydroxyderricin(4-HD), the major active ingredients of Angelica keiskei Koidzumi, is a potent selective monoamine oxidase (MAO) inhibitor with mild inhibitory effect on dopamine β-hydroxylase.
GC63628 4-Hydroxymidazolam

4-羟基咪达唑仑

4-Hydroxymidazolam 是 Midazolam 的一种主要代谢产物。Midazolam 是一种有效的苯二氮卓类药物，具有促进精神安定的活性。
GC39307 4-Methylamino antipyrine

4-(甲氨基)安替比林
An active metabolite of metamizole
GC60523 4-Methylamino antipyrine hydrochloride

安乃近杂质C
An active metabolite of metamizole
GC11606 4-Methylbenzylidene camphor

4-甲基苄亚基樟脑; 4-MBC; Enzacamene
A UV blocker with estrogenic effects
GC12737 4-Methylhistamine dihydrochloride

2-(4-甲基-1H-咪唑基-5-基)乙胺二盐酸盐
A histamine H₄ receptor agonist
GC42443 4-Methylumbelliferyl 6-thio-Palmitate-β-D-Glucopyranoside

4-甲基-7-[[6-S-(1-氧代十六烷基)-6-硫代-BETA-D-吡喃葡萄糖基]氧基]-2H-1-苯并吡喃-2-酮
A fluorogenic substrate of PPT/CLN1
GC40510 4-Methylumbelliferyl-α-D-Galactopyranoside

4-甲基伞形酮-α-D-吡喃半乳糖苷; 4MU-α-Gal
A fluorogenic substrate of α-galactosidase
GC42447 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside

4-甲基香豆素-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖苷
A fluorogenic substrate for β-hexosaminidases
GC49244 4-oxo Isotretinoin

4-酮13-顺式维甲酸
An active metabolite of isotretinoin
GC14311 4-Phenyl-1,2,3,4-tetrahydroisoquinoline hydrochloride dopamine release inhibitor
GC46675 4-Phenyl-2-pyrrolidinone

4-苯基-2-吡咯烷酮
A precursor and synthetic intermediate
GC18631 4BP-TQS An agonist of α7 subunit-containing nAChRs
GC40053 5α,6α-epoxy Cholestanol

胆固醇-5Α,6Α-环氧化物,NSC 18176
5α,6α-epoxy Cholestanol 是一种胆固醇衍生物，可以通过线粒体中的细胞色素P450酶系催化生成或是在脂质过氧化过程中诱导生成，可调节胆汁酸的生物合成、诱导肿瘤细胞的分化和死亡。
GC46715 5α,6β-Dihydroxycholestanol-d7

Cholestanetriol-d7, 5α,6β-di-OHC-d7
An internal standard for the quantification of 5α,6β-dihydroxycholestanol
GC48843 5α-Androst-16-en-3α-ol

(3α,5α)-16-烯-3-甾醇
A pheromone with diverse biological activities
GC49540 5α-Androst-2-ene-17-one

5alpha-雄甾-2-烯-17-酮
A steroid and synthetic intermediate
GC18582 5'-hydroxy Meloxicam

5'-羟基美洛昔康
A metabolite of meloxicam
GC60527 5,7-Dimethoxyluteolin

5,7-二甲氧基木犀草素
5,7-Dimethoxyluteolin，一种5,7-二甲基木犀草素衍生物，是一种多巴胺转运蛋白(DAT)活化剂，EC50值为3.417μM。
GC90889 5-(3'-Hydroxyphenyl)-γ-Valerolactone

δ-(3'-Hydroxyphenyl)-γ-Valerolactone, 5-(3'-Hydroxyphenyl)-γ-VL, δ-(3'-Hydroxyphenyl)-γ-VL, (3'-hydroxy)-PVL

多种多酚的代谢产物。
GC60026 5-AAM-2-CP

N-[(6-氯吡啶-3-基)甲基]乙酰胺

5-AAM-2-CP是一种Acetamiprid的主要代谢产物。Acetamiprid是一种广泛使用的新烟碱类杀虫剂，是nAChR的激动剂。
GC60027 5-AMAM-2-CP 5-AMAM-2-CP是一种Acetamiprid的主要代谢产物。Acetamiprid是一种广泛使用的新烟碱类杀虫剂，是nAChR的激动剂。
GC31234 5-HT1A modulator 1 5-HT1Amodulator1对5HT1A，肾上腺素能α1和多巴胺D2受体具有非常高的亲和力，IC50分别为2±0.3nM，10±3nM和40±9nM。
GC60028 5-HT1A modulator 2 hydrochloride

8-甲氧基-2-四氢萘胺
5-HT1Amodulator2hydrochloride是8-OH-DPAT的一种衍生物，5-HT1Amodulator2hydrochloride是5-HT1A的调节剂，与5-HT1A结合的Ki值为53nM。
GC32655 5-HT2 antagonist 1 5-HT2antagonist1是一种有效的5-HT2receptor拮抗剂，同时对α1adrenoceptor有微弱地抑制作用。
GC32664 5-HT2A antagonist 1 5-HT2Aantagonist1是来自专利US5728835A和JP1007727的5-HT2A拮抗剂。5-HT2Aantagonist1可能用于治疗心血管疾病的研究。
GC71279 5-HT2A receptor agonist-3
5-HT2A receptor agonist-3Ki=2.5nM、对5-HT2A的选择性是结构相似的5-HT2C受体的124倍。
GC65568 5-HT2B antagonist-1 WAY-388264-A is a bioactive compound.
GC31263 5-HT3 antagonist 1 5-HT3antagonist1是一种有效的选择性的serotonin3(5-HT3)receptor拮抗剂。
GC31247 5-HT3 antagonist 2 5-HT3antagonist2是5-HT3受体的拮抗剂。
GC65983 5-HT3 antagonist 5 5-HT3 antagonist 5 是一种喹喔啉 -2- 甲酰胺化合物，是 5-HT3 受体拮抗剂。5-HT3 antagonist 5 对 5-HT3 激动剂和 2- 甲基 -5-HT 也具有拮抗作用，并在小鼠中表现出抗抑郁效果。
GC31227 5-HT3-In-1 5-HT3-In-1来自专利EP0748807A1，化合物实例8。它有抑制5-HT3的活性。
GC30314 5-HT4 antagonist 1 5-HT4antagonist1是一个5-HT4受体拮抗剂，其pKi值为9.6。
GC31144 5-HT7 agonist 1 5-HT7agonist1是一种选择性的5-HT7受体激动剂，IC50值为222.93nM，可用于研究与5-HT7受体相关的疾病，例如中枢神经系统疾病。
GC49655 5-hydroxy Buspirone

5-羟基-8-[4-(嘧啶-2-基)-1-哌嗪基丁基]-8-氮杂螺[4,5]癸烷-7,9-二酮
A metabolite of buspirone
GC49119 5-hydroxy Flunixin

5-羟基氟尼辛
A metabolite of flunixin
GC52172 5-hydroxy Indole-3-acetic Acid-d6

5-HIAA-d6, 5-Hydroxyindoleacetic Acid-d6, 5-hydroxy IAA-d6
An internal standard for the quantification of 5-hydroxy indole-3-acetic acid
GC49315 5-hydroxy Indomethacin

O-去甲吲哚美辛
A metabolite of indomethacin
GC52106 5-hydroxy Isatin

5-羟基靛红
An inhibitor of MAO-A
GC42550 5-hydroxy-6-methoxy (S)-Duloxetine

度洛西汀杂质
A metabolite of (S)-duloxetine
GC42553 5-hydroxy-Nω-methyl Tryptamine (oxalate)

5-羟基-N-甲基色胺草酸盐

A serotonin metabolite and 5-HT₇ receptor agonist
GC11626 5-Iodo-A-85380 dihydrochloride α4β2 and α6β2 nicotinic acetylcholine receptors agonist
GC14225 5-Iodo-A-85380, 5-trimethylstannyl N-BOC derivative Precursor to ligand for the α4β2 nicotinic receptor
GC14940 5-Methoxytryptamine

5-甲氧基色胺
GC64182 5-Methoxytryptamine hydrochloride

5-甲氧基色胺盐酸盐
5-Methoxytryptamine hydrochloride，一种 Melatonin 的代谢物，是一种非选择性 5-HT 受体激动剂。5-Methoxytryptamine hydrochloride 对 5-HT3 受体没有亲和力。5-Methoxytryptamine hydrochloride 也是一种有效的抗氧化剂，并具有辐射防护作用。
GC14604 5-Methylfurmethiodide

5-甲呋硫碘
muscarinic agonist
GC46706 5-Methyltetrahydrofolic Acid (hydrate)

5-methyl THF, Prefolic A
叶酸的生物活性形式
GC17477 5-Nonyloxytryptamine oxalate A potent 5-HT_1Dβ receptor agonist