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Home >> Signaling Pathways >> Neuroscience >> COX

COX(环氧合酶)

COX (cyclooxygenase) is an enzyme that is responsible for formation of important biological mediators called prostanoids, including prostaglandins, prostacyclin and thromboxane.

Products for  COX

  1. Cat.No. 产品名称 Information
  2. GC40262 α-Humulene

    ALPHA-律草烯,Humulene; α-Caryophyllene

     A sesquiterpene with diverse biological activities
  3. GC10873 α-Spinasterol

    菠甾醇

     A TRPV1 antagonist
  4. GC41623 β-Elemonic Acid

    β-岚香酮酸

     A triterpene with anticancer activity
  5. GC41658 (±)-2-hydroxy Ibuprofen

    2-羟基布洛芬; (±)-2-Hydroxy Ibuprofen

     A metabolite of ibuprofen
  6. GC46290 (±)-Ibuprofen-d3

    氘代布洛芬,(±)-Ibuprofen-d3

     An Analytical Reference Standard
  7. GC49515 (±)-Ibuprofen-d3 (sodium salt)

    布洛芬钠-D3,(±)-Ibuprofen-d3 sodium

     An internal standard for the quantification of (±)-ibuprofen
  8. GC45278 (±)-Ketoprofen-d3

    酮洛芬D3,RP-19583-d3

     An internal standard for the quantification of (±)-ketoprofen
  9. GN10605 (+)-Catechin hydrate

    (+)-水合儿茶素

     A polyphenolic flavonoid with diverse biological activities
  10. GC11049 (+/-)-Sulfinpyrazone

    磺吡酮,G-28315

     An inhibitor of uric acid reabsorption
  11. GC40842 (-)-Catechin

    (-)-儿茶素; (-)-Cianidanol; (-)-Catechuic acid

     A diastereoisomer of catechin
  12. GC32957 (-)-Catechin gallate ((-)-Catechin 3-gallate)

    儿茶素没食子酸酯; (-)-Catechin 3-gallate; (-)-Catechin 3-O-gallate

     A polyphenol with diverse biological activities
  13. GC10603 (-)-epicatechin gallate

    表儿茶素没食子酸酯; Epicatechin gallate; ECG; (-)-Epicatechin 3-O-gallate

     A natural polyphenol with diverse protective actions
  14. GC13114 (S)-(+)-Ibuprofen

    (S)-(+)-布洛芬; (S)-Ibuprofen

     An active enantiomer of ibuprofen
  15. GC64804 (S)-(+)-Ibuprofen D3

    (S)-布洛芬-D3,(S)-Ibuprofen D3

     (S)-(+)-Ibuprofen D3 ((S)-Ibuprofen D3) 是(S)-(+)-Ibuprofen 的氘代物。(S)-(+)-Ibuprofen 是 Ibuprofen 的 S 型异构体，可抑制 COX-1 和 COX-2 活性，IC50 为 2.1 μM 和 1.6 μM。(S)-(+)-Ibuprofen 具有止痛，抗炎和解热作用。
  16. GC18022 (S)-Flurbiprofen

    (S)-氟比洛芬,Esflurbiprofen

     The COX-active enantiomer of flurbiprofen
  17. GC15977 (S)-Ketoprofen

    (S)-(+)-酮洛芬; (S)-Ketoprofen; Dexketoprofen

     A potent inhibitor of COX-1 and COX-2
  18. GC41389 (S)-Ketorolac

    (1S)-5-苯基-2,3-二氢-1H-吡啶-1-羧酸,(-)-Ketorolac

     A non-selective COX inhibitor
  19. GC14820 (S)-Naproxen

    萘普生; (S)-Naproxen

     An NSAID and COX inhibitor
  20. GC49179 (S)-O-Desmethyl Naproxen

    萘普生杂质A

     A metabolite of (S)-naproxen
  21. GC41761 1-(6-Methoxy-2-naphthyl)ethanol

    DL-6-甲氧基-ALPHA-甲基-2-萘甲醇

     A potential impurity found in commercial naproxen preparations
  22. GC60447 1-Hydroxy-ibuprofen

    1-羟基异丁基苯基-1'-甲基丙酸

     1-hydroxy Ibuprofen 是非甾体类抗炎药 (NSAID) 和非选择性 COX 抑制剂布洛芬的代谢物。
  23. GC49366 1-Salicylate Glucuronide

    Salicyl Phenolic Glucuronide, Salicylic Acid Phenolic Glucuronide

     A metabolite of salicylic acid and aspirin
  24. GN10799 20(S)-Ginsenoside Rg3

    20(S)-人参皂苷 Rg3; 20(S)-Propanaxadiol; S-ginsenoside Rg3

     20(S)-Ginsenoside Rg3是从人参中提取的稀有人参皂苷（Na+：IC50 = 32.2±4.5μM；hKv1.4：IC50 = 32.6±2.2μM）。
  25. GC42201 3,3'-Diiodo-L-thyronine

    3,3'-二碘甲腺原氨酸,3,3'-T2

     A metabolite of thyroid hormone
  26. GC91680 4-Acetamido Antipyrine

    4-AAAP,NSC 331807

     4-Acetamido antipyrine (4-AAAP) is an active metabolite of the non-opioid analgesic and antipyretic prodrug metamizole .
  27. GC39307 4-Methylamino antipyrine

    4-(甲氨基)安替比林

     An active metabolite of metamizole
  28. GC60523 4-Methylamino antipyrine hydrochloride

    安乃近杂质C

     An active metabolite of metamizole
  29. GC90889 5-(3'-Hydroxyphenyl)-γ-Valerolactone

    δ-(3'-Hydroxyphenyl)-γ-Valerolactone, 5-(3'-Hydroxyphenyl)-γ-VL, δ-(3'-Hydroxyphenyl)-γ-VL, (3'-hydroxy)-PVL

    多种多酚的代谢产物。
  30. GC49119 5-hydroxy Flunixin

    5-羟基氟尼辛

     A metabolite of flunixin
  31. GC49315 5-hydroxy Indomethacin

    O-去甲吲哚美辛

     A metabolite of indomethacin
  32. GC49183 6-hydroxy Etodolac

    6-羟基依托度酸

     A metabolite of etodolac
  33. GC16153 6-methoxy Naphthalene Acetic Acid

    6-甲基萘乙酸,6-MNA

     A non-selective COX inhibitor
  34. GC15338 8,11,14-Eicosatriynoic Acid

    8,11,14-ETI

     A cyclooxygenase and lipoxygenase inhibitor
  35. GC14302 9,12-Octadecadiynoic Acid

    Ro 3-1314

     An inhibitor of both COX and lipoxygenase
  36. GC35012 [10]-Shogaol

    10-姜烯酚

     A phenol with diverse biological activities
  37. GC35013 [8]-Shogaol

    8-姜烯酚

     [8]-Shogaol，生姜中的一种刺激性酚类化合物，具有抗血小板活性 (IC50=5 μM) 和抑制 COX-2 (IC50=17.5 μM)。[8]-Shogaol 诱导人白血病细胞凋亡。
  38. GC15902 Aceclofenac

    醋氯芬酸

     An NSAID
  39. GC42691 Aceclofenac ethyl ester A potential impurity found in commercial preparations of aceclofenac
  40. GC42692 Aceclofenac methyl ester

    Aceclofenac Impurity D

     A potential impurity in commercial preparations of aceclofenac
  41. GC10454 Acemetacin

    阿西美辛; TVX 1322

     An NSAID
  42. GC12917 Acetaminophen

    对乙酰氨基酚; Paracetamol; 4-Acetamidophenol; 4'-Hydroxyacetanilide

    An analgesic and antipyretic compound
  43. GC64137 Acetaminophen-d3

    扑热息痛D3,Paracetamol-d3; 4-Acetamidophenol-d3; 4'-Hydroxyacetanilide-d3

     Acetaminophen-d3 (Paracetamol-d3) 是 Acetaminophen 的氘代物。Acetaminophen (Paracetamol) 是选择性环氧合酶-2 (COX-2) 的抑制剂，IC50 值为 25.8 μM。Acetaminophen 是一种有效的肝 N-乙酰转移酶 2 (NAT2) 抑制剂。Acetaminophen 是广泛使用的解热和止痛剂。
  44. GC46781 Acetaminophen-d4

    对乙酰氨基酚 d4

     An internal standard for the quantification of acetaminophen
  45. GC31693 Adelmidrol

    阿地米屈

     Adelmidrol is an analogue of palmitoylethanolamide (PEA) with anti-inflammatory activities.
  46. GC62830 AG-024322 AG-024322 是一种有效的 ATP 竞争性的 pan-CDK 抑制剂，抑制 CDK1， CDK2， CDK4 的 Ki 值在 1-3 nM 范围内。AG-024322 在体内表现出广谱抗肿瘤活性和清晰的靶标调控。AG-024322 诱导细胞凋亡 (apoptosis)。
  47. GC61689 Alminoprofen

    阿明洛芬,EB-382

     Alminoprofen是苯丙酸类非甾体抗炎药(NSAID)。Alminoprofen同时具有抑制分泌磷脂酶A2(sPLA2)活性和抗环氧化酶(COX-2)的活性。
  48. GC14740 Amfenac Sodium Monohydrate

    氨芬酸钠水合物

     A COX inhibitor and the active metabolite of nepafenac
  49. GC14104 Ampiroxicam

    安吡昔康; CP 65703

     A prodrug of piroxicam
  50. GC33484 Ampyrone (4-Aminoantipyrine)

    4-氨基安替比林

     4-Aminoantipyrine(Ampyrone) is a metabolite of aminopyrine with analgesic, anti-inflammatory, and antipyretic properties. It is used as a reagent for biochemical reactions producing peroxides or phenols.
  51. GN10685 Anemarsaponin B

    知母皂苷 B

     Anemarsaponin B 是一种甾体皂苷。

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