COX(环氧合酶)

COX (cyclooxygenase) is an enzyme that is responsible for formation of important biological mediators called prostanoids, including prostaglandins, prostacyclin and thromboxane.

Products for COX

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Cat.No. 产品名称 Information
GC33861 Inulicin (1-O-Acetylbritannilactone)

旋覆花内酯,1-O-Acetylbritannilactone
A sesquiterpene lactone with diverse biological activities
GC39134 Isofraxidin

异嗪皮啶
Isofraxidin (6,8-Dimethoxyumbelliferone), a bioactive coumarin compound isolated from the functional foods Siberian ginseng and Apium graveolens, is an anti-bacterial, anti-oxidant, and anti-inflammatory agent.
GC39534 Isoxicam

伊索昔康
Isoxicam 是一种口服有效的非甾体抗炎剂，可用于关节炎的研究。Isoxicam 是一种非选择性的 COX-1 和 COX-2 抑制剂。
GC41645 Jacaric Acid

8(Z),10(E),12(Z)-Octadecatrienoic Acid
A conjugated PUFA
GN10645 Jaceosidin

棕矢车菊素
A natural methylated trihydroxyflavone
GC13339 Ketoprofen

酮洛芬; RP-19583
A non-selective COX inhibitor
GC15179 Ketorolac

酮咯酸; RS37619
An NSAID and COX inhibitor
GC47528 Ketorolac (calcium salt)

酮咯酸钙盐,RS37619 hemicalcium
An NSAID and COX inhibitor
GC60966 Ketorolac D5

酮咯酸D5
An internal standard for the quantification of ketorolac
GC16594 Ketorolac tromethamine salt

酮咯酸氨丁三醇; Ketorolac Tromethamine; Ketorolac tris salt; RS37619 tromethamine salt
An NSAID and COX inhibitor
GC60225 Licarin A

利卡灵A,(+)-Licarin A
LicarinA((+)-LicarinA)，可从多种植物中分离得到，显着降低二硝基苯肼-人血清白蛋白(DNP-HSA)刺激的RBL-2H3细胞。具有抗过敏作用。LicarinA降低TNF-α和PGD2产生，和COX-2表达。
GC16721 Licofelone

利克飞龙
A dual inhibitor of COX-1/COX-2 and 5-LO
GC13572 Lornoxicam

氯诺昔康; Chlortenoxicam; Ro 13-9297
A COX inhibitor and NSAID
GC48639 Lornoxicam-d4

氯诺昔康-D4,Chlortenoxicam-d4; Ro 13-9297-d4
An internal standard for the quantification of lornoxicam
GC14013 Losartan Carboxaldehyde

氯沙坦甲醛,DuP-167|EXP3179
A losartan metabolite with anti-inflammatory actions
GC36482 Loxoprofen

洛索洛芬
An NSAID and a prodrug form of loxoprofen-SRS
GC60228 Loxoprofen sodium

洛索洛芬钠
An NSAID and a prodrug form of loxoprofen-SRS
GC91681 Loxoprofen-SRS Loxoprofen-SRS is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 0.5 and 0.39 for recombinant human COX-1 and COX-2, respectively) and an active metabolite of the prodrug loxoprofen .
GC12941 Lumiracoxib

罗美昔布; COX-189
A selective inhibitor of COX-2
GN10022 luteolin-6-C-glucoside

异荭草素; Homoorientin
A flavonoid with diverse biological activities
GC30610 LY 178002
LY178002是一种有效的5-lipoxygenase，phospholipaseA2抑制剂，对5-lipoxygenase的IC50值为0.6μM，能够抑制人多形核白细胞产生LTB4，同时可相对较弱地抑制cyclooxygenase的活性。
GC38066 Mavacoxib

吗伐考昔
Mavacoxib (Trocoxil) is a selective, long-acting cyclooxygenase-2 (COX-2) inhibitor. Mavacoxib is a novel nonsteroidal anti-inflammatory drug (NSAID).
GC11096 Mefenamic Acid

甲芬那酸
A NSAID and COX-2 inhibitor
GC61038 Mefenamic acid D4

甲芬那酸 D4
An internal standard for the quantification of mefenamic acid
GC11762 Meloxicam (Mobic)

美洛昔康
A selective COX-2 inhibitor
GC40065 Meloxicam-d3

美洛昔康 d3
An internal standard for the quantification of meloxicam
GC44167 Metamizole (sodium salt)

安乃近
A nonopioid prodrug
GC31737 Metamizole sodium hydrate

安乃近水合物
Metamizole (Dipyrone) sodium hydrate is a potent inhitior of cyclooxygenase (COX) with strong analgesic as well as antipyretic and spasmolytic properties.
GC47639 Metamizole-d3 (sodium salt)

Dipyrone-d3
A neuropeptide with diverse biological activities
GC31943 Methyl Salicylate (Wintergreen oil)

水杨酸甲酯,Wintergreen oil
Methyl salicylate (Betula oil, Gaultheria oil, Methyl 2-hydroxybenzoate, Natural wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. It is an agonist for TRPA1 and TRPV1.
GC41634 Metyrosine

甲酪氨酸
An inhibitor of tyrosine hydroxylase
GC61843 Mofezolac

莫苯唑酸
A COX-1 inhibitor
GC17980 N-(2-phenylethyl)-Indomethacin amide

N-2PIA
A selective, reversible inhibitor of COX-2
GC15372 N-(3-hydroxyphenyl)-Arachidonoyl amide

3-HPAA
An irreversible COX-2 inhibitor
GC15959 N-(3-pyridyl)-Indomethacin amide

N-3PyIA
Potent and selective reversible inhibitor of COX-2
GC10611 N-(4-acetamidophenyl)-Indomethacin amide

N-4AIA
Potent and selective reversible inhibitor of COX-2
GC16440 N-acetyl-2-carboxy Benzenesulfonamide A COX-1/COX-2 inhibitor
GC17306 N-tert-butyl-α-Phenylnitrone

N-叔丁基-α-苯基硝酮
A spin trap
GC40686 N-trans-Feruloyltyramine

N-反式-阿魏酰酪胺,N-feruloyltyramine; Moupinamide
A phenolic amide with diverse biological activities
GC13422 Nabumetone

萘丁美酮; BRL14777
An NSAID and a prodrug form of 6-methoxy naphthalene acetic acid
GC47734 Nabumetone-d3

萘丁美酮-D3,BRL14777-d3
An internal standard for the quantification of nabumetone
GC32026 Naproxen etemesil (LT-NS 001)

(S)-2-(甲磺酰)乙基2-(6-甲氧基萘-2-基)丙酯,LT-NS 001; MX 1094
Naproxen etemesil (LT-NS 001) 是一种亲脂性、非酸性、无活性的萘普生前药，一旦被吸收就会水解成具有药理活性的萘普生。
GC17975 Naproxen Sodium

萘普生钠
Naproxen sodium 是一种 COX-1 和 COX-2 抑制剂，在细胞试验中 IC50 分别为 8.72 和 5.15 μM。
GC12684 NCX 4040

NO-Aspirin
NCX 4040 (NO-Aspirin) 是一种非甾体抗炎药 (NSAID)，是一种一氧化氮 (NO) 释放形式的阿司匹林。
GC13896 NCX 466 cyclooxygenase (COX)-inhibiting nitric oxide (NO) donor
GN10429 Neochlorogenic acid

新绿原酸; trans-5-O-Caffeoylquinic acid
A phenolic compound with diverse biological activities
GC13637 Nepafenac

奈帕芬胺; AHR 9434; AL 6515
A prodrug from of amfenac
GC36721 Nepafenac D5

奈帕芬胺 D5; AHR-9434-d5; AL-6515-d5
An internal standard for the quantification of nepafenac
GC18084 Nimesulide

尼美舒利; R805
An NSAID and COX2 inhibitor
GC39583 Nimesulide D5

尼美舒利 D5
An internal standard for the quantification of nimesulide