COX(环氧合酶)

Cat.No. 产品名称 Information

GC36747 Nitroaspirin

2-乙酰氧基苯甲酸-3-硝酸甲基苯酯,NCX 4016

Nitroaspirin (NCX 4016) 是一氧化氮 (NO) 供体和阿司匹林的硝基衍生物，Aspirin 与 Nitroaspirin 联合以抑制环加氧酶。Nitroaspirin (NCX 4016) 具有抗血栓形成和抗血小板特性，并作为 COX-1 的直接和不可逆抑制剂。Nitroaspirin (NCX 4016) 通过下调 EGFR/PI3K/STAT3 信号传导和调节 Bcl-2 家族蛋白，在顺铂耐药人卵巢癌细胞中引起细胞周期停滞和凋亡。

GC34028 Nitroflurbiprofen (HCT 1206)

硝基氟比洛芬; HCT 1206; NO-flurbiprofen; Nitroxybutyl flurbiprofen

Nitroflurbiprofen (HCT 1206) 是一种环氧合酶 (COX) 抑制剂，具有提供一氧化氮 (NO) 的特性，可调节门脉高压性肝硬化大鼠肝内血管张力的增加。

GC44439 NO-Indomethacin

NCX 2121

An NSAID-NO donor hybrid with anti-cancer activity

GC12241 NS 398

抑制剂

A selective COX2 inhibitor

GC14999 O-Acetyl Salicylhydroxamic Acid

AcSHA,O-ASHA

An irreversible, non-selective inhibitor of COX-1 and COX-2

GC49316 O-Desmethyl-N-deschlorobenzoyl Indomethacin A metabolite of indomethacin

GC63478 Ocarocoxib Ocarocoxib, 是一种有效的 COX-2 (环加氧酶- 2) 抑制剂，是一种兽医用非甾体抗炎药。

GC49098 Olsalazine-13C6 An internal standard for the quantification of olsalazine

GC12114 Oxaprozin

奥沙普秦; Oxaprozinum; Wy21743

An NSAID and COX inhibitor

GC36828 Oxaprozin D4

Wy-21743 D4

Oxaprozin D4是Oxaprozin的氘代化合物标准品。

GC69640 Oxaprozin-d4

奥沙普秦D4; Wy-21743-d₄

Oxaprozin-d4 是 Oxaprozin 的氘代物。

GC49054 Oxaprozin-d5

Oxaprozinum-d5; Wy21743-d5

An internal standard for the quantification of oxaprozin

GC40651 Oxyphenbutazone

羟布宗

An NSAID

GC32640 Pamicogrel (KBT3022)

帕米格雷; KBT3022

A COX inhibitor and an antiplatelet agent

GC14849 Paradol

姜酮酚; [6]-Gingerone; [6]-Paradol

A phenolic ketone with diverse biological activities

GC36852 Parecoxib

帕瑞昔布; SC 69124

A prodrug form of valdecoxib

GC17051 Parecoxib Sodium

帕瑞昔布钠; SC 69124A

A prodrug form of valdecoxib

GC70553 Pelubiprofen Pelubiprofen是一种口服活性非甾体抗炎药，属于2-芳基丙酸家族，对COX-2活性具有相对选择性的作用。

GC60283 Pentagamavunon-1

PGV-1

Pentagamavunon-1 (PGV-1) 是Curcumin 的类似物，具有口服活性，通过多个机制诱导凋亡信号，如抑制COX-2 和 VEGF。Pentagamavunon-1 (PGV-1) 可抑制 NF-κB 的激活。

GC44597 Peonidin (chloride)

氯化芍药素,YGM-6 chloride

A plant pigment with antioxidant properties

GC15928 Phenacetin

非那西丁; Acetophenetidin

An Analytical Reference Standard

GC66429 Phenacetin-d5

Acetophenetidin-d5

Phenacetin-d5 (Acetophenetidin-d5) 是 Phenacetin 的氘代物。Phenacetin (Acetophenetidin) 是一种非阿片类解热化合物，可用于缓解疼痛的研究。Phenacetin 是一种选择性的 COX-3 抑制剂。Phenacetin 能作为人肝微粒体和大鼠体内 CYP1A2 的探针。

GC61180 Phenidone

菲尼酮

Phenidone (1-phenyl-3-pyrazolidinone), a dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LOX), is an organic compound that is primarily used as a photographic developer.

GC15008 Phenylbutazone

保泰松

An NSAID and COX inhibitor

GC65108 Phenylbutazone(diphenyl-d10)

保泰松 d10

An NSAID and COX inhibitor

GC69699 Phenylbutazone-13C12 Phenylbutazone-13C12 是 13C12 标记的 Phenylbutazone。Phenylbutazone 是有效的前列腺素 H 合酶 (PHS) 过氧化物酶的还原辅助因子。Phenylbutazone 是一种肝毒素，是非甾体类抗炎剂 (NSAID)。Phenylbutazone 诱导肌肉盲样蛋白1 (MBNL1) 表达，有用于强直性脊柱炎研究的潜力。

GC49128 Phenylbutazone-d9

保泰松 d9

An internal standard for the quantification of phenylbutazone

GC16790 Piroxicam

吡罗昔康; CP-16171

A COX inhibitor and NSAID

GC61193 Piroxicam D3

吡罗昔康 D3; CP-16171 D3

An internal standard for the quantification of piroxicam

GN10395 Prim-O-glucosylcimifugin

升麻素苷；升麻苷

A chromone with diverse biological activities

GC66258 Propacetamol

丙帕他莫

A prodrug form of acetaminophen

GC19706 Propacetamol hydrochloride

盐酸丙帕他莫

A prodrug form of acetaminophen

GC33876 Propyphenazone (4-Isopropylantipyrine)

异丙安替比林; 4-Isopropylantipyrine; Isopropylphenazone

Propyphenazone(4-Isopropylantipyrine, Isopropyrine), an analgesic and antipyretic agent, is a selective cyclooxygenase-2 inhibitor with anti-inflammatory activity.

GC71602 Propyphenazone-d3 Propyphenazone-d3是氘标记的苯丙酮。

GC14847 Psoralidin

补骨脂定

A furanocoumarin with anti-cancer activity

GC60311 PTUPB PTUPB是一种新型的COX-2和sEH双抑制剂，IC₅₀ 值分别为 1.26 nM 和 0.9μM。

GC17367 Rebamipide

瑞巴派特; OPC12759; Proamipide

A gastroprotective agent and mucin secretagogue

GC61234 Rebamipide D4

瑞巴派特 D4; OPC12759-d4; Proamipide-d4

An internal standard for the quantification of rebamipide

GC63398 Rebamipide mofetil Rebamipide mofetil is an orally active prodrug of Rebamipide (OPC12759). Rebamipide induces COX-2 expression, increases PGE2 levels, and enhances gastric mucosal defense in a COX-2-dependent manner.

GC61235 Regaloside B

王百合苷 B

RegalosideB是一种从Liliumlongiflorum中分离出来的苯丙烷。RegalosideB可以抑制iNOS和COX-2的表达，具有抗炎活性。

GC61238 Rehmapicrogenin

地黄苦苷元

Rehmapicrogenin可从Rehmanniaglutinosa的根部分离得到，通过抑制iNOS、COX-2和IL-6表现出有效的抗炎作用。

GC38198 Revaprazan hydrochloride

盐酸瑞伐拉赞

Revaprazan Hydrochloride (YH1885) is a new reversible proton pump inhibitor with long-lasting acid-suppressive effects. Revaprazan Hydrochloride reversibly inhibits H(+)/K(+)-ATPase via binding to the K+-binding site of the pump.