GlpBio

COX

COX(环氧合酶)

COX (cyclooxygenase) is an enzyme that is responsible for formation of important biological mediators called prostanoids, including prostaglandins, prostacyclin and thromboxane.

COX 相关产品(291)

  • GC18022 structure
    GC18022(S)-Flurbiprofen
    CAS: 51543-39-6
    纯度: >98.00%

    The COX-active enantiomer of flurbiprofen

  • GC18369 structure
    GC18369Cimicoxib
    CAS: 265114-23-6

    A selective inhibitor of COX-2

  • GC18427 structure
    GC18427CAY10452
    CAS: 170569-87-6
    纯度: >99.50%

    A non-apoptotic, selective COX-2 inhibitor

  • GC19353 structure
    GC19353TFAP
    CAS: 1011244-68-0
    纯度: >99.50%

    A selective COX-1 inhibitor

  • GC19706 structure
    GC19706Propacetamol hydrochloride
    CAS: 66532-86-3

    A prodrug form of acetaminophen

  • GC30027 structure
    GC30027S-(+)-Marmesin ((+)-Marmesin)
    CAS: 13849-08-6
    纯度: >98.00%

    A coumarin with anticancer activity

  • GC30610 structure
    GC30610LY 178002
    CAS: 107889-32-7

    LY178002是一种有效的5-lipoxygenase，phospholipaseA2抑制剂，对5-lipoxygenase的IC50值为0.6μM，能够抑制人多形核白细胞产生LTB4，同时可相对较弱地抑制cyclooxygenase的活性。

  • GC31440 structure
    GC31440Syringaldehyde
    CAS: 134-96-3
    纯度: >98.00%

    A polyphenol with diverse biological activities

  • GC31693 structure
    GC31693Adelmidrol
    CAS: 1675-66-7
    纯度: >98.00%

    Adelmidrol is an analogue of palmitoylethanolamide (PEA) with anti-inflammatory activities.

  • GC31706 structure
    GC31706Ginsenoside Rg5
    CAS: 186763-78-0
    纯度: >98.00%

    A ginsenoside with diverse biological activities

  • GC31707 structure
    GC31707Chebulagic acid
    CAS: 23094-71-5
    纯度: >98.00%

    A polyphenol with diverse biological activities

  • GC31737 structure
    GC31737Metamizole sodium hydrate
    CAS: 5907-38-0
    纯度: >98.00%

    Metamizole (Dipyrone) sodium hydrate is a potent inhitior of cyclooxygenase (COX) with strong analgesic as well as antipyretic and spasmolytic properties.

  • GC31749 structure
    GC31749Columbin
    CAS: 546-97-4
    纯度: >98.50%

    A diterpenoid furanolactone with diverse biological activities

  • GC31813 structure
    GC31813RWJ 63556
    CAS: 190967-35-2

    RWJ63556是一种可口服的COX-2selective/5-lipoxygenase抑制剂，具有抗炎活性。

  • GC31818 structure
    GC31818Flosulide (ZK 38997)
    CAS: 80937-31-1

    Flosulide (ZK 38997) 是一种有效的选择性 COX-2 抑制剂，用于治疗炎症性疾病。

  • GC31826 structure
    GC31826Thioflosulide (L-745337)
    CAS: 158205-05-1

    Thioflosulide (L-745337) (L-745337) 是一种选择性 cyclooxygenase-2 (COX2) 抑制剂，IC50 为 2.3 nM，具有抗炎活性。

  • GC31835 structure
    GC31835S-2474
    CAS: 158089-95-3

    S-2474是COX-2和5-lipoxygenase的抑制剂，在人完整的细胞中，对COX-2和COX-1的IC50值分别为11nM和27μM，为一种非甾体抗炎药。

  • GC31943 structure
    GC31943Methyl Salicylate (Wintergreen oil)
    CAS: 119-36-8

    Methyl salicylate (Betula oil, Gaultheria oil, Methyl 2-hydroxybenzoate, Natural wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. It is an agonist for TRPA1 and TRPV1.

  • GC31956 structure
    GC31956Tilmacoxib (JTE522)
    CAS: 180200-68-4
    纯度: >99.00%

    Tilmacoxib (JTE522) (JTE522) 是一种高度选择性、时间依赖性和不可逆的人 COX-2 抑制剂，在酶试验中 IC50 为 85 nM。

  • GC31960 structure
    GC31960SC57666
    CAS: 158959-32-1
    纯度: >98.50%

    SC57666是选择性的COX2抑制剂，IC50值为26nM。

  • GC31962 structure
    GC31962COX-2-IN-1
    CAS: 787623-48-7

    COX-2-IN-1是一个强效的COX-2抑制剂，其IC50值为3.9μM。

  • GC31965 structure
    GC31965Timegadine (SR1368)
    CAS: 71079-19-1

    Timegadine (SR1368) 是一种新型抗炎剂，被发现是一种有效的、竞争性的环加氧酶 (COX) 和脂加氧酶抑制剂，IC50 范围为 5 nM（洗涤过的兔血小板）至 20 μM（大鼠脑） ) 用于 COX 和 100 μ；M 用于马血小板匀浆的胞质溶胶部分和洗涤过的兔血小板中的脂加氧酶。

  • GC31967 structure
    GC31967COX/5-LO-IN-1
    CAS: 154355-75-6

    COX/5-LO-IN-1是cylooxygenase和5-lipoxygenase的抑制剂，用于炎症性和过敏性疾病的研究。

  • GC31985 structure
    GC31985SC58451
    CAS: 168433-84-9

    SC58451是一个强效的，有选择性的COX-2抑制剂。