COX(环氧合酶)

COX (cyclooxygenase) is an enzyme that is responsible for formation of important biological mediators called prostanoids, including prostaglandins, prostacyclin and thromboxane.

Products for COX

Cat.No. 产品名称 Information
GC15977 (S)-Ketoprofen
(S)-(+)-酮洛芬; (S)-Ketoprofen; Dexketoprofen
A potent inhibitor of COX-1 and COX-2
GC11049 (+/-)-Sulfinpyrazone
磺吡酮,G-28315
An inhibitor of uric acid reabsorption
GC12591 Diflunisal
二氟尼柳,MK-647
A non-selective COX inhibitor
GC14584 Fenofibric acid
非诺贝特酸; FNF acid
An agonist of PPARα, PPARγ, and PPARδ and an active metabolite of fenofibrate
GC13746 Fenbufen
芬布芬; CL-82204
An NSAID
GC15059 Sulindac sulfide
cis-Sulindac sulfide
An active metabolite of sulindac
GC17975 Naproxen Sodium
萘普生钠
Naproxen sodium 是一种 COX-1 和 COX-2 抑制剂，在细胞试验中 IC50 分别为 8.72 和 5.15 μM。
GC10603 (-)-epicatechin gallate
表儿茶素没食子酸酯; Epicatechin gallate; ECG; (-)-Epicatechin 3-O-gallate
(-)-epicatechin gallate是一种天然黄烷醇，属于茶多酚中的酯型儿茶素类化合物，(-)-epicatechin gallate通过抑制环加氧酶-1(COX-1)发挥抗炎作用（IC₅₀=7.5μM）。
GC12397 Firocoxib
非罗考昔; ML 1785713
An inhibitor of COX-2
GC17817 SC 58125
1-[(4-甲基磺酰基)苯基]-3-三氟甲基-5-(4-氟苯基)吡唑
A selective COX-2 inhibitor
GC12684 NCX 4040
NO-Aspirin
NCX 4040 (NO-Aspirin) 是一种非甾体抗炎药 (NSAID)，是一种一氧化氮 (NO) 释放形式的阿司匹林。
GC10973 SC 236
4-(5-(4-氯苯基)-3-(三氟甲基)-1H-
A potent, selective COX-2 inhibitor
GC11853 Tenidap
替尼达普,CP-66248
A COX-1 selective NSAID
GC16881 FR 122047 hydrochloride
1-[[4,5-双(4-甲氧基苯基)-2-噻唑]羰基]-4-甲基哌嗪盐酸盐
A selective COX-1 inhibitor
GC12156 DuP 697
5-溴-2-（4-氟苯基）-3-（4-甲基磺酰基苯基）噻吩
A selective COX-2 inhibitor
GC12241 NS 398
抑制剂
A selective COX2 inhibitor
GC10873 α-Spinasterol
菠甾醇
A TRPV1 antagonist
GC13896 NCX 466 cyclooxygenase (COX)-inhibiting nitric oxide (NO) donor
GC15634 SC 560
5-(4-氯苯基)-1-(4-甲氧基苯基)-3-(三氟甲基)-1H-吡唑
A selective inhibitor of COX-1
GC12411 RHC 80267
1,6-双(环己基脒基羰基氨基)己烷,U-57908
RHC 80267是一种有效的、选择性二酰基甘油脂酶（DAGL）抑制剂，RHC 80267还能够抑制胆碱酯酶活性（IC₅₀=4μM），可抑制环氧化酶（COX）活性和磷脂酰胆碱的水解。
GC18133 ATB-346
ATB-346
An H₂S-releasing NSAID
GC12917 Acetaminophen
对乙酰氨基酚; Paracetamol; 4-Acetamidophenol; 4'-Hydroxyacetanilide

An analgesic and antipyretic compound
GC11090 Diclofenac
双氯芬酸
Diclofenac是一种强效的非选择性环氧化酶（COX）抑制剂，在CHO细胞中对人源COX-1和COX-2的IC₅₀值分别为4nM和1.3nM；对羊源COX-1和COX-2的IC₅₀值分别为5.1μM和0.84μM。
GC15902 Aceclofenac
醋氯芬酸
An NSAID
GC15179 Ketorolac
酮咯酸; RS37619
An NSAID and COX inhibitor
GC17882 Fenoprofen Calcium
非诺洛芬钙
An NSAID
GC16721 Licofelone
利克飞龙
A dual inhibitor of COX-1/COX-2 and 5-LO
GC10454 Acemetacin
阿西美辛; TVX 1322
An NSAID
GC17367 Rebamipide
瑞巴派特; OPC12759; Proamipide
A gastroprotective agent and mucin secretagogue
GC13626 Zaltoprofen
扎托布洛芬; CN100
A non-selective COX inhibitor
GC11096 Mefenamic Acid
甲芬那酸
A NSAID and COX-2 inhibitor
GC15395 Tolfenamic Acid
托芬那酸; GEA 6414
An NSAID with anticancer activity
GC13569 Flunixin Meglumin
氟尼辛葡甲胺
A COX inhibitor
GC13466 Flufenamic acid
氟芬那酸
An NSAID and COX inhibitor
GC14261 Diclofenac Sodium
双氯芬酸钠; GP 45840
Diclofenac Sodium是一种强效的非选择性环氧化酶（COX）抑制剂，在CHO细胞中对人源COX-1和COX-2的IC₅₀值分别为4nM和1.3nM；对羊源COX-1和COX-2的IC₅₀值分别为5.1μM和0.84μM。
GC18084 Nimesulide
尼美舒利; R805
An NSAID and COX2 inhibitor
GC10006 Tenoxicam
替诺昔康; Ro-12-0068
An NSAID and COX-1 inhibitor
GC13572 Lornoxicam
氯诺昔康; Chlortenoxicam; Ro 13-9297
A COX inhibitor and NSAID
GC15928 Phenacetin
非那西丁; Acetophenetidin
An Analytical Reference Standard
GC13300 Triflusal
三氟柳
An inhibitor of platelet aggregation
GC12114 Oxaprozin
奥沙普秦; Oxaprozinum; Wy21743
An NSAID and COX inhibitor
GC13422 Nabumetone
萘丁美酮; BRL14777
An NSAID and a prodrug form of 6-methoxy naphthalene acetic acid
GC12941 Lumiracoxib
罗美昔布; COX-189
A selective inhibitor of COX-2
GC14499 Fenoprofen calcium hydrate
非诺洛芬钙盐二水合物,Fenoprofen calcium salt dihydrate
An NSAID
GC14622 Diclofenac Potassium
双氯芬酸钾
Diclofenac Potassium是一种强效的非选择性环氧化酶（COX）抑制剂，在CHO细胞中对人源COX-1和COX-2的IC₅₀值分别为4nM和1.3nM；对羊源COX-1和COX-2的IC₅₀值分别为5.1μM和0.84μM。
GC14587 Diclofenac Diethylamine
双氯芬酸二乙胺
An NSAID and a COX inhibitor
GC17341 Carprofen
卡洛芬
An NSAID used in animals
GC15410 Bufexamac
丁苯羟酸; Bufexamic acid
An NSAID and a class IIb HDAC inhibitor
GC13039 Bromfenac Sodium
溴芬酸钠
A COX-2 inhibitor
GC17776 Asaraldehyde
细辛醛; Asaronaldehyde; Asaraldehyde; 2,4,5-trimethoxy-Benzaldehyde
Asarylaldehyde (Asaronaldehyde) 是一种 COX-2 抑制剂，可显着抑制环氧合酶 II (COX-2) 的活性，IC50 值为 100 μg/mL。