GlpBio

TFAP

目录号: GC19353纯度: >99.50%同义词: N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide
A selective COX-1 inhibitor
TFAP
Cas No.: 1011244-68-0
规格价格库存数量操作
1mg¥212.00现货
1
5mg¥494.00现货
1
10mg¥763.00现货
1
25mg¥1,317.00现货
1
50mg¥1,969.00现货
1
100mg¥2,847.00现货
1
10mM (in 1mL DMSO)¥657.00现货
1
电话: 400-920-5774Email: sales@glpbio.cn

文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor, with an IC50 of 0.8 uM.

TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor, with an IC50 of 0.8 uM, while that against COX-2 is over 200 uM.

References:
[1]. Kakuta H, et al. Identification of urine metabolites of TFAP, a cyclooxygenase-1 inhibitor. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1840-3.

产品文档 Product Documents

Purity:>99.50%

化学性质Chemical Properties

CAS 号
1011244-68-0
同义词
N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide
SMILES
O=C(NC1=NC=C(N)C=C1)C2=CC=C(C(F)(F)F)C=C2
分子式
C13H10F3N3O
分子量
281.23 g/mol
溶解性
DMSO : ≥ 155 mg/mL (551.15 mM)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol