COX(环氧合酶)

COX (cyclooxygenase) is an enzyme that is responsible for formation of important biological mediators called prostanoids, including prostaglandins, prostacyclin and thromboxane.

Products for COX

Cat.No. 产品名称 Information
GC14104 Ampiroxicam
安吡昔康; CP 65703
A prodrug of piroxicam
GC14740 Amfenac Sodium Monohydrate
氨芬酸钠水合物
A COX inhibitor and the active metabolite of nepafenac
GC15008 Phenylbutazone
保泰松
An NSAID and COX inhibitor
GC13339 Ketoprofen
酮洛芬; RP-19583
A non-selective COX inhibitor
GC12013 Sodium salicylate
水杨酸钠; Salicylic acid sodium salt; 2-Hydroxybenzoic acid sodium salt
水杨酸钠（水杨酸钠盐）抑制环加氧酶 2（COX-2）活性，与转录因子（NF-κB）激活无关。
GC16508 Salicylic acid
水杨酸; 2-Hydroxybenzoic acid
An Analytical Reference Standard
GC16594 Ketorolac tromethamine salt
酮咯酸氨丁三醇; Ketorolac Tromethamine; Ketorolac tris salt; RS37619 tromethamine salt
An NSAID and COX inhibitor
GC16716 Sulindac
舒林酸; MK-231
A non-selective COX inhibitor
GC13114 (S)-(+)-Ibuprofen
(S)-(+)-布洛芬; (S)-Ibuprofen
An active enantiomer of ibuprofen
GC16662 Etodolac
依托度酸; AY-24236
An NSAID
GC16077 Deracoxib
地拉考昔; SC 046; SC 46; SC 59046
An NSAID and selective COX-2 inhibitor
GC17051 Parecoxib Sodium
帕瑞昔布钠; SC 69124A
A prodrug form of valdecoxib
GC10516 Rofecoxib
罗非考昔; MK 966
A COX-2 inhibitor
GC14020 Valdecoxib
伐地考昔; SC 65872
A COX-2 inhibitor
GC12391 Xanthohumol
黄腐醇
Xanthohumol是啤酒花中主要的异戊烯基黄酮类化合物，能够抑制二酰甘油酰基转移酶（DGAT），IC₅₀值为50.3μM。
GC16790 Piroxicam
吡罗昔康; CP-16171
A COX inhibitor and NSAID
GC11762 Meloxicam (Mobic)
美洛昔康
A selective COX-2 inhibitor
GC17556 Indomethacin
吲哚美辛; Indometacin
Indomethacin(吲哚美辛)是一种有效的口服活性 COX1/2 抑制剂,COX-1 和 COX-2 的IC50 值分别为 18 nM 和 26 nM。
GC17863 Ibuprofen
布洛芬; (±)-Ibuprofen
An NSAID and non-selective COX inhibitor
GC16294 Ibuprofen Lysine
布洛芬赖氨酸盐,(±)-Ibuprofen L-lysine
Ibuprofen ((±)-Ibuprofen) L-lysine 是一种有效的具有口服活性的选择性 COX-1 抑制剂，IC50 值为 13 μM.
GC13637 Nepafenac
奈帕芬胺; AHR 9434; AL 6515
A prodrug from of amfenac
GC14475 Celecoxib
塞来昔布; SC 58635
Celecoxib是一种高度选择性的环氧合酶-2（COX-2）抑制剂，IC₅₀值为40nM。
GC14849 Paradol
姜酮酚; [6]-Gingerone; [6]-Paradol
A phenolic ketone with diverse biological activities
GC17419 Iguratimod
艾拉莫德; T614
A DMARD and COX-2 inhibitor
GC11768 FK 3311
N-[4-乙酰基-2-(2,4-二氟苯氧基)苯基]-甲烷磺酰胺,FK-3311;FK3311
A COX-2 inhibitor
GC10429 Etoricoxib
依托考昔; MK-0663; L-791456
A selective COX-2 inhibitor
GC15706 Aspirin (Acetylsalicylic acid)
阿司匹林; Acetylsalicylic Acid; ASA
A non-selective, irreversible COX inhibitor
GN10022 luteolin-6-C-glucoside
异荭草素; Homoorientin
A flavonoid with diverse biological activities
GN10685 Anemarsaponin B
知母皂苷 B
Anemarsaponin B 是一种甾体皂苷。
GN10004 EsculentosideA
商陆皂苷甲
EsculentosideA (EsA)，一种从商陆根中分离得到的三萜皂苷。
GN10080 Byakangelicol
白当归脑
A furanocoumarin with diverse biological activities
GN10645 Jaceosidin
棕矢车菊素
A natural methylated trihydroxyflavone
GN10430 D-(-)-Salicin
水杨苷; D-(?)-Salicin; Salicoside
A non-selective COX inhibitor
GN10429 Neochlorogenic acid
新绿原酸; trans-5-O-Caffeoylquinic acid
A phenolic compound with diverse biological activities
GN10388 Gallic acid
没食子酸; 3,4,5-Trihydroxybenzoic acid
A phenol with diverse biological activities
GN10605 (+)-Catechin hydrate
(+)-水合儿茶素
A polyphenolic flavonoid with diverse biological activities
GN10220 Ginsenoside Rb3
人参皂苷 Rb3; Gypenoside IV
A steroid glycoside with diverse biological activities
GN10549 Ginsenoside Rd
人参皂苷 Rd; Gypenoside VIII
A natural steroid glycoside with diverse effects
GN10799 20(S)-Ginsenoside Rg3
20(S)-人参皂苷 Rg3; 20(S)-Propanaxadiol; S-ginsenoside Rg3
20(S)-Ginsenoside Rg3是从人参中提取的稀有人参皂苷（Na⁺：IC₅₀ = 32.2±4.5μM；hKv1.4：IC₅₀ = 32.6±2.2μM）。
GN10395 Prim-O-glucosylcimifugin
升麻素苷；升麻苷
A chromone with diverse biological activities
GN10039 Rutaecarpine
吴茱萸次碱; Rutecarpine
Rutaecarpine是一种从吴茱萸中分离出的吲哚并吡啶喹唑啉生物碱，已知在细胞水平上以0.28μM的IC₅₀抑制COX-2。