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Home >> Signaling Pathways >> Neuroscience >> COX

COX(环氧合酶)

COX (cyclooxygenase) is an enzyme that is responsible for formation of important biological mediators called prostanoids, including prostaglandins, prostacyclin and thromboxane.

Products for  COX

  1. Cat.No. 产品名称 Information
  2. GC48858 APHS A COX inhibitor
  3. GC17776 Asaraldehyde

    细辛醛; Asaronaldehyde; Asaraldehyde; 2,4,5-trimethoxy-Benzaldehyde

     Asarylaldehyde (Asaronaldehyde) 是一种 COX-2 抑制剂，可显着抑制环氧合酶 II (COX-2) 的活性，IC50 值为 100 μg/mL。
  4. GC15706 Aspirin (Acetylsalicylic acid)

    阿司匹林; Acetylsalicylic Acid; ASA

     A non-selective, irreversible COX inhibitor
  5. GC63683 Aspirin-d3

    乙酰水杨酸-D3,Acetylsalicylic Acid-d3; ASA-d3

     Aspirin-d3 (Acetylsalicylic Acid-d3) 是 Aspirin 的氘代物。Aspirin是非选择性和不可逆的 COX-1 和 COX-2 抑制剂，IC50 分别为5，210 μg/mL。
  6. GC42859 Aspirin-d4

    阿司匹林D4,Acetylsalicylic Acid-d4; ASA-d4

     An internal standard for the quantification of aspirin
  7. GC18133 ATB-346

    ATB-346

     An H2S-releasing NSAID
  8. GC45820 Balsalazide-d4 Balsalazide-d4 是氘标记的 Balsalazide。
  9. GC35493 Benzoylgomisin O

    苯甲酰戈米辛O

     Benzoylgomisin O 是从 Schisandra rubriflora 中分离的化合物，对 15-LOX、COX-1、COX-2 酶有抑制作用，且具有抗炎活性。
  10. GC13039 Bromfenac Sodium

    溴芬酸钠

     A COX-2 inhibitor
  11. GC15410 Bufexamac

    丁苯羟酸; Bufexamic acid

     An NSAID and a class IIb HDAC inhibitor
  12. GN10080 Byakangelicol

    白当归脑

     A furanocoumarin with diverse biological activities
  13. GC40352 Cafestol

    咖啡醇

     Cafestol是咖啡中主要活性成分之一，是一种咖啡特异性二萜类化合物，具有ERK2抑制活性。
  14. GC17341 Carprofen

    卡洛芬

     An NSAID used in animals
  15. GC32841 Catechin ((+)-Catechin)

    儿茶素; (+)-Catechin; Cianidanol; Catechuic acid

     (+)-Catechin (Cianidanol, Catechinic acid, Catechuic acid) is an antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.
  16. GC70218 Cavidine Cavidine((+)-Cavidine)是一种具有抗炎活性的选择性COX-2抑制剂。
  17. GC43149 CAY10404 A COX-2 inhibitor
  18. GC18427 CAY10452

    塞来昔布杂质3

     A non-apoptotic, selective COX-2 inhibitor
  19. GC14475 Celecoxib

    塞来昔布; SC 58635

     Celecoxib是一种高度选择性的环氧合酶-2（COX-2）抑制剂，IC50值为40nM。
  20. GC49152 Celecoxib Carboxylic Acid

    羧酸塞来昔布

     An inactive metabolite of celecoxib
  21. GC68849 Celecoxib-d3

    SC 58635-d3

     Celecoxib-d3 是 Celecoxib 的氘代物。Celecoxib 是一种选择性的 COX-2 抑制剂，IC50 为 40 nM。
  22. GC47070 Celecoxib-d7

    塞来昔布-D7,SC 58635-d7

     An internal standard for the quantification of celecoxib
  23. GC31707 Chebulagic acid

    诃子鞣酸

     A polyphenol with diverse biological activities
  24. GC18369 Cimicoxib

    UR-8880

     A selective inhibitor of COX-2
  25. GC31749 Columbin

    古伦宾

     A diterpenoid furanolactone with diverse biological activities
  26. GC31962 COX-2-IN-1

    COX-2-IN-1是一个强效的COX-2抑制剂，其IC50值为3.9μM。
  27. GC68016 COX-2-IN-6 COX-2-IN-6 是一种肠道限制性选择性环氧化酶-2（COX-2）抑制剂，用于结直肠癌的化学预防。
  28. GC31967 COX/5-LO-IN-1

    Atreleuton analog

     COX/5-LO-IN-1是cylooxygenase和5-lipoxygenase的抑制剂，用于炎症性和过敏性疾病的研究。
  29. GC32030 COX2-IN-1 COX2-IN-1是选择性的，诱导型的COX2抑制剂，IC50值为0.24μM。COX2-IN-1是具有抗炎和止痛活性的抗炎物。
  30. GC38224 Crocin II

    西红花苷II

     Crocin II (Crocin B, Crocetin gentiobiosylglucosyl ester, Tricrocin), a carotenoid chemical compound that is found in the flowers crocus and gardenia, is an antioxidant and neural protective agent.
  31. GN10430 D-(-)-Salicin

    水杨苷; D-(?)-Salicin; Salicoside

     A non-selective COX inhibitor
  32. GC38184 Dehydrodiisoeugenol

    脱氢二异丁香酚

     Dehydrodiisoeugenol, a naturally occurring lignan from Aristolochia taliscana (Aristolochiaceae), acts as a potent anti-inflammatory agent and shows various pharmacological activities, including anti-lipid peroxidation, anti-bacteial function, and hepatic drug metabolism enzyme inhibition.
  33. GC38431 Dehydroevodiamine

    脱氢吴茱萸碱

     An alkaloid with diverse biological activities
  34. GC16077 Deracoxib

    地拉考昔; SC 046; SC 46; SC 59046

     An NSAID and selective COX-2 inhibitor
  35. GC64136 Desmethyl Naproxen-d3 Desmethyl Naproxen-d3 是 Desmethyl Naproxen。Desmethyl Naproxen 是抗炎剂 Naproxen 的代谢物。
  36. GC11090 Diclofenac

    双氯芬酸

     双氯芬酸是一种有效的非选择性抗炎药，作为 COX 抑制剂，对人 COX-1 和 COX-2 在 CHO 细胞中的 IC50 分别为 4 和 1.3 nM ，对羊 COX-1 的 IC50 分别为 5.1 和 0.84 μM和 COX-2，分别。
  37. GC47212 Diclofenac amide

    1-(2,6-二氯苯基)-1,3-二氢-2H-吲哚-2-酮

     A prodrug form of diclofenac
  38. GC14587 Diclofenac Diethylamine

    双氯芬酸二乙胺

     An NSAID and a COX inhibitor
  39. GC43447 Diclofenac methyl ester

    双氯酚甲酯

     A prodrug form of diclofenac
  40. GC14622 Diclofenac Potassium

    双氯芬酸钾

     双氯芬酸钾是一种有效的非选择性抗炎剂，作为 COX 抑制剂，对人 COX-1 和 COX-2 在 CHO 细胞中的 IC50 分别为 4 和 1.3 nM ，对羊 COX- 的 IC50 分别为 5.1 和 0.84 μM。 1 和 COX-2，分别。
  41. GC14261 Diclofenac Sodium

    双氯芬酸钠; GP 45840

     An NSAID and a COX inhibitor
  42. GC47213 Diclofenac-d4

    双氯芬酸 D4

     An internal standard for the quantification of diclofenac
  43. GC12591 Diflunisal

    二氟尼柳,MK-647

     A non-selective COX inhibitor
  44. GC12156 DuP 697

    5-溴-2-（4-氟苯基）-3-（4-甲基磺酰基苯基）噻吩

     A selective COX-2 inhibitor
  45. GC12229 Eicosatetraynoic Acid

    花生四烯酸,ETYA

     A nonspecific inhibitor of cyclooxygenases and lipoxygenases
  46. GC47287 Eltenac

    依尔替酸

     A non-selective COX inhibitor
  47. GC63804 Enflicoxib

    E 6087

     Enflicoxib (E 6087) 是一种非甾体抗炎化合物，可选择性抑制环氧合酶 2 (COX-2)。Enflicoxib 不抑制环氧合酶-1 (COX-1)。E-6087 在动物模型中显示出抗炎、镇痛和解热活性。
  48. GN10004 EsculentosideA

    商陆皂苷甲

     EsculentosideA (EsA)，一种从商陆根中分离得到的三萜皂苷。
  49. GC38678 Ethyl Caffeate

    咖啡酸乙酯

     Ethyl caffeate, a naturally occurring compound found in Bidens pilosa, suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2 and PGE2 in vitro.
  50. GC43635 Ethyl p-methoxycinnamate

    对甲氧基肉桂酸乙酯

     A natural product with diverse actions
  51. GC16662 Etodolac

    依托度酸; AY-24236

     An NSAID

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