GlpBio

α-Spinasterol

目录号: GC10873纯度: >99.00%同义词: 菠甾醇
A TRPV1 antagonist
α-Spinasterol
Cas No.: 481-18-5
规格价格库存数量操作
1mg¥765.00现货
1
5mg¥2,070.00现货
1
10mg¥3,209.00现货
1
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文献被引

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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    31, 1291–1307 (2021)

产品描述 Description

α-Spinasterol, isolated from Spinacia oleracea, has antibacterial activity[1]. α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects. α-Spinasterol inhibits COX-1 andCOX-2 activities with IC50 values of 16.17 μM and 7.76 μM, respectively[2].

References:
[1]. Brusco I, et al. α-Spinasterol: a COX inhibitor and a transient receptor potential vanilloid 1 antagonist presents an antinociceptive effect in clinically relevant models of pain in mice. Br J Pharmacol. 2017 Dec;174(23):4247-4262.
[2]. Yang X, et al. A novel method for synthesis of α-spinasterol and its antibacterial activities in combination with ceftiofur. Fitoterapia. 2017 Jun;119:12-19.

产品文档 Product Documents

Purity:>99.00%

化学性质Chemical Properties

CAS 号
481-18-5
同义词
菠甾醇
化学名
(3S,5S,9R,10S,13R,14R,17R)-17-((2R,5S,E)-5-ethyl-6-methylhept-3-en-2-yl)-10,13-dimethyl-2,3,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
SMILES
O[C@@H]1C[C@H]2[C@@](CC1)(C)[C@@H]3C([C@H]4[C@@](CC3)(C)[C@@H]([C@@H](/C=C/[C@@H](CC)C(C)C)C)CC4)=CC2
分子式
C29H48O
分子量
412.69 g/mol
溶解性
DMF: 1 mg/ml,Ethanol: 0.25 mg/mL
保存条件
4°C, protect from light
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol