COX
COX(环氧合酶)
COX (cyclooxygenase) is an enzyme that is responsible for formation of important biological mediators called prostanoids, including prostaglandins, prostacyclin and thromboxane.
COX 相关产品(291)
- GC12229Eicosatetraynoic AcidCAS: 1191-85-1纯度: >98.00%
A nonspecific inhibitor of cyclooxygenases and lipoxygenases
- GC12391XanthohumolCAS: 6754-58-1纯度: >99.50% / >98.00%
Xanthohumol是啤酒花中主要的异戊烯基黄酮类化合物，能够抑制二酰甘油酰基转移酶（DGAT），IC 50 值为50.3μM。
- GC14584Fenofibric acidCAS: 42017-89-0纯度: >99.50%
An agonist of PPARα, PPARγ, and PPARδ and an active metabolite of fenofibrate
- GC14622Diclofenac PotassiumCAS: 15307-81-0纯度: >98.00%
Diclofenac Potassium是一种强效的非选择性环氧化酶（COX）抑制剂，在CHO细胞中对人源COX-1和COX-2的IC₅₀值分别为4nM和1.3nM；对羊源COX-1和COX-2的IC₅₀值分别为5.1μM和0.84μM。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC11203 | ZLJ-6 | 1051931-39-5 | - | |
Dual inhibitor of cyclooxygenase/5-lipoxygenase | ||||
| GC11721 | Sulindac sulfone | 59864-04-9 | - | |
A metabolite of sulindac | ||||
| GC11768 | FK 3311 | 116686-15-8 | >98.00% | |
A COX-2 inhibitor | ||||
| GC12013 | Sodium salicylate | 54-21-7 | >99.50% | |
水杨酸钠（水杨酸钠盐）抑制环加氧酶 2（COX-2）活性，与转录因子（NF-κB）激活无关。 | ||||
| GC12114 | Oxaprozin | 21256-18-8 | >99.50% | |
An NSAID and COX inhibitor | ||||
| GC12229 | Eicosatetraynoic Acid | 1191-85-1 | >98.00% | |
A nonspecific inhibitor of cyclooxygenases and lipoxygenases | ||||
| GC12391 | Xanthohumol | 6754-58-1 | >99.50% / >98.00% | |
Xanthohumol是啤酒花中主要的异戊烯基黄酮类化合物，能够抑制二酰甘油酰基转移酶（DGAT），IC 50 值为50.3μM。 | ||||
| GC12397 | Firocoxib | 189954-96-9 | >98.00% | |
An inhibitor of COX-2 | ||||
| GC12411 | RHC 80267 | 83654-05-1 | >99.50% | |
RHC 80267是一种有效的、选择性二酰基甘油脂酶（DAGL）抑制剂，RHC 80267还能够抑制胆碱酯酶活性（IC₅₀=4μM），可抑制环氧化酶（COX）活性和磷脂酰胆碱的水解。 | ||||
| GC12591 | Diflunisal | 22494-42-4 | >99.50% | |
A non-selective COX inhibitor | ||||
| GC12719 | Indomethacin heptyl ester | 282728-47-6 | - | |
A potent, non-selective COX-2 inhibitor | ||||
| GC13039 | Bromfenac Sodium | 91714-93-1 | - | |
A COX-2 inhibitor | ||||
| GC13042 | Inotilone | 906366-79-8 | - | |
A COX-2 inhibitor | ||||
| GC13132 | FR122047 (hydrate) | - | - | |
selective inhibitor of COX-1 | ||||
| GC13402 | Tryptanthrin | 13220-57-0 | >98.50% | |
An alkaloid with diverse actions | ||||
| GC13466 | Flufenamic acid | 530-78-9 | >99.50% | |
An NSAID and COX inhibitor | ||||
| GC13637 | Nepafenac | 78281-72-8 | >99.50% | |
A prodrug from of amfenac | ||||
| GC13746 | Fenbufen | 36330-85-5 | >98.50% | |
An NSAID | ||||
| GC14013 | Losartan Carboxaldehyde | 114798-36-6 | - | |
A losartan metabolite with anti-inflammatory actions | ||||
| GC14302 | 9,12-Octadecadiynoic Acid | 2012-14-8 | >98.00% | |
An inhibitor of both COX and lipoxygenase | ||||
| GC14499 | Fenoprofen calcium hydrate | 71720-56-4 | >99.50% | |
An NSAID | ||||
| GC14584 | Fenofibric acid | 42017-89-0 | >99.50% | |
An agonist of PPARα, PPARγ, and PPARδ and an active metabolite of fenofibrate | ||||
| GC14587 | Diclofenac Diethylamine | 78213-16-8 | >99.50% | |
An NSAID and a COX inhibitor | ||||
| GC14622 | Diclofenac Potassium | 15307-81-0 | >98.00% | |
Diclofenac Potassium是一种强效的非选择性环氧化酶（COX）抑制剂，在CHO细胞中对人源COX-1和COX-2的IC₅₀值分别为4nM和1.3nM；对羊源COX-1和COX-2的IC₅₀值分别为5.1μM和0.84μM。 | ||||