GlpBio

5-HT Receptor

5-HT Receptor(5-羟色胺受体)

5-HT receptor (5-hydroxytryptamine receptors) is a group of GPCRs (G protein-coupled receptors) and LGICs (ligand-gated ion channels) found in the central and peripheral nervous systems.

5-HT Receptor 相关产品(419)

  • GC10108 structure
    GC10108WAY-100635
    CAS: 162760-96-5
    纯度: >98.00%

    WAY-100635是一种具有高效性选择的5-hydroxytryptamine 1A（5-HT1A）受体拮抗剂，IC 50 值为0.91nM，K i 值为0.39nM。

  • GC10121 structure
    GC10121Tianeptine sodium
    CAS: 30123-17-2
    纯度: >99.50%

    An atypical antidepressant

  • GC10450 structure
    GC10450PRX-08066
    CAS: 866206-54-4

    A 5-HT 2B receptor antagonist

  • GC10460 structure
    GC10460Rizatriptan Benzoate
    CAS: 145202-66-0
    纯度: >99.50%

    A 5-HT 1B and 5-HT 1D receptor agonist

  • GC10630 structure
    GC10630Zimelidine dihydrochloride
    CAS: 60525-15-7

    5-HT re-uptake inhibitor

  • GC10769 structure
    GC10769SB269970 HCl
    CAS: 261901-57-9
    纯度: >98.50% / >98.00%

    SB269970 HCl是一种强效且选择性的5-HT 7 受体拮抗剂，具有高亲和力 (pK i = 8.9)。

  • GC10799 structure
    GC10799Iloperidone hydrochloride
    CAS: 1299470-39-5

    An atypical antipsychotic

  • GC10822 structure
    GC10822Clozapine N-oxide (CNO)
    CAS: 34233-69-7
    纯度: >98.00%

    Clozapine N-oxide（CNO）是一种强效的多巴胺拮抗剂，也是一种选择性肌动蛋白M4受体（EC50=11 nM）激动剂。

  • GC10848 structure
    GC10848BMY 7378
    CAS: 21102-95-4

    BMY 7378是一种α 1D -肾上腺素能受体（α 1D -AR）的选择性拮抗剂，pk i 值为8.89，也是血清素1A受体（5-HT 1A R）的混合激动剂和拮抗剂。

  • GC10876 structure
    GC10876Vilazodone Hydrochloride
    CAS: 163521-08-2
    纯度: >98.00%

    An SSRI and a partial agonist of 5-HT 1A

  • GC10911 structure
    GC10911Venlafaxine hydrochloride
    CAS: 99300-78-4
    纯度: >99.50%

    Venlafaxine hydrochloride是一种具有口服活性的5-羟色胺和去甲肾上腺素再摄取抑制剂 （SNRIs; Serotonin-norepinephrine reuptake inhibitors），对配体与人NE和5-HT转运蛋白结合的Ki值分别为2480nM和82nM。

  • GC10945 structure
    GC10945Tandospirone
    CAS: 87760-53-0
    纯度: >99.00%

    Tandospirone (SM-3997) 是一种有效的选择性 5-HT1A 受体部分激动剂，Ki 为 27 nM。

  • GC10985 structure
    GC10985MDL 72832 hydrochloride
    CAS: 113777-40-5

    ligand for 5-HT1A receptor, potent and selective

  • GC11020 structure
    GC11020Ziprasidone
    CAS: 146939-27-7
    纯度: >98.00%

    齐拉西酮 (CP-88059) 是一种口服活性抗精神病药，是一种 5-HT 和多巴胺受体拮抗剂的组合。

  • GC11166 structure
    GC11166Alosetron Hydrochloride
    CAS: 122852-69-1
    纯度: >99.50%

    A 5-HT 3 receptor antagonist

  • GC11384 structure
    GC11384BTS 54-505 hydrochloride
    CAS: 84484-78-6

    Potent SNRI,sibutramine metabolite

  • GC11495 structure
    GC11495Lofepramine
    CAS: 23047-25-8
    纯度: >99.50%

    A tricyclic antidepressant

  • GC11517 structure
    GC11517SEA0400
    CAS: 223104-29-8
    纯度: >98.00%

    A selective inhibitor of the Na + /Ca 2+ exchanger

  • GC11521 structure
    GC11521Ziprasidone HCl
    CAS: 122883-93-6

    An atypical antipsychotic

  • GC11570 structure
    GC11570Desvenlafaxine
    CAS: 93413-62-8

    An active metabolite of venlafaxine

  • GC11651 structure
    GC11651Ondansetron hydrochloride dihydrate
    CAS: 103639-04-9
    纯度: >99.00%

    An Analytical Reference Material

  • GC11709 structure
    GC11709Fluoxetine HCl
    CAS: 56296-78-7
    纯度: >99.50%

    An Analytical Reference Material

  • GC11714 structure
    GC11714Prucalopride
    CAS: 179474-81-8
    纯度: >99.50%

    A selective 5-HT 4 receptor agonist

  • GC11729 structure
    GC11729RS 127445
    CAS: 199864-87-4

    RS 127445是一种具有口服活性的高选择性5-羟色胺受体2B（5-HT 2B ）受体拮抗剂，pK i 为9.5，对5-HT 2B 的选择性是对5-HT 2A 、5-HT 2C 等其他相关受体的1000倍以上。