Cell Cycle/Checkpoint(细胞周期/检查点)

Cell Cycle

Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0. read more

Products for Cell Cycle/Checkpoint

Cat.No. 产品名称 Information
GC40702 α-D-Galactopyranosylphenyl isothiocyanate

Α-D-吡喃半乳糖基苯基异硫氰酸酯
Used in neoglycoprotein preparation
GC45226 β-BHC

β-HCH, β-Hexachlorocyclohexane, β-Lindane
β-BHC is an isomer of the organochlorine pesticide γ-lindane that is a potential impurity found in commercial preparations of lindane.
GC62383 (±)-ErSO (±)-ErSO 是 ErSO 的消旋体。ErSO 是选择性预期未折叠蛋白反应 (a-UPR) 激活物。
GC41676 (±)-Nornicotine

3-(吡咯烷-2-基)吡啶
An active metabolite of nicotine and nAChR agonist
GC49482 (±)-Nornicotine-d4

氘代降烟碱
An internal standard for the quantification of (±)-nornicotine
GC46308 (±)-Sitagliptin-d4 (hydrochloride) A neuropeptide with diverse biological activities
GC41684 (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane

BMC, Vectrase P
A compound used in protein purification
GC40802 (±)12(13)-DiHOME

Isoleukotoxin diol
A diol form of (±)12,13-EpOME
GC41656 (±)2-(14,15-Epoxyeicosatrienoyl) Glycerol

(±)214,15EG
A cytochrome P450 metabolite of 2-AG
GC45890 (+)-Abscisic Acid-d6

(+)-脱落酸-d6; (S)-(+)-Abscisic acid-d6; ABA-d6
An internal standard for the quantification of (+)-abscisic acid
GC70332 (+)-Erinacin A (+)-Erinacin A是一种抗癌化合物，可以从蘑菇猴头菇中分离出来。
GC62728 (1E)-CFI-400437 dihydrochloride CFI-400437 is a potent and selective polo-like kinase 4 (PLK4) inhibitor.
GC41698 (D)2-Rh 110 (trifluoroacetate salt)

D2R, (Asp)2-Rhodamine 110, Rhodamine 110 bis-(L-aspartic acid amide)
A fluorogenic caspase substrate
GC41268 (E)-2-Hexadecenal

trans-2-Hexadecenal
A long-chain fatty aldehyde
GC41701 (E)-2-Hexadecenal Alkyne A click chemistry probe for a sphingolipid degradation product
GC46335 (E)-Fenpyroximate

唑螨酯
A phenoxypyrazole acaricide
GC10419 (R)-CCG-1423 A stereoisomer of CCG-1423, a Rho inhibitor
GC16429 (R)-DRF053 dihydrochloride cdk/CK1 inhibitor,potent and ATP-competitive
GC72915 (R)-MRT199665 (R)-MRT199665是MRT199665的异构体。
GC41719 (R)-nitro-Blebbistatin

R(-)7Desmethyl8nitro Blebbistatin
A more stable form of (+)-blebbistatin
GC46347 (S)-(+)-Methoprene

S-(+)-烯虫酯,(+)-Methoprene; (7S)-Methoprene
An insect growth regulator and Met agonist
GC41557 (S)-3'-amino Blebbistatin

(-)-3'-amino Blebbistatin, m-amino Blebbistatin, meta-amino Blebbistatin
A more stable form of (–)-blebbistatin
GC41484 (S)-3'-hydroxy Blebbistatin

(-)-3'-hydroxy Blebbistatin, meta-hydroxy-Blebbistatin, m-hydroxy-Blebbistatin
A more stable form of (–)-blebbistatin
GC52192 (S)-4'-nitro-Blebbistatin

(-)-4'-nitro-Blebbistatin, p-nitro-Blebbistatin, para-nitro-Blebbistatin
A more stable and less phototoxic form of (–)-blebbistatin
GC14497 (S)-CCG-1423 A stereoisomer of CCG-1423, a Rho inhibitor
GC34999 (S)-Ceralasertib

(S)-AZD6738
(S)-Ceralasertib 从专利 WO2011154737A1 中获取，化合物 II，IC50 为 2.578 nM。(S)-Ceralasertib 是一种有效的选择性亚砜亚胺吗啉代嘧啶 ATR 抑制剂，具有优异的临床前物化和药代动力学 (PK) 特征。(S)-Ceralasertib 水溶性改善，并且消除 CYP3A4 时间依赖性抑制。
GC46351 (S)-CR8 An inhibitor of cyclin-dependent kinases
GC41737 (S)-Glycyl-H-1152 (hydrochloride)

Rho Kinase Inhibitor IV
A ROCK inhibitor
GC40145 (S)-Laudanosine

(+)-Laudanosine, L-Laudanosine, L-(+)-Laudanosine, NSC 35045
The (S) enantiomer of laudanosine
GC41739 (S)-nitro-Blebbistatin

S(-)7Desmethyl8nitro Blebbistatin
A more stable form of (–)-blebbistatin
GC40121 (Z-DEVD)2-Rh 110 (trifluoroacetate salt)

(Z-Asp-Glu-Val-Asp)2-Rhodamine 110
A fluorogenic substrate for caspase-3
GC41742 (Z-IETD)2-Rh 110 (trifluoroacetate salt)

(Z-Ile-Glu-Thr-Asp)2-R110, Rhodamine 110 bis-(N-CBZ-IETD)2
A fluorogenic substrate for caspase-8
GC18275 1,2-Dihexadecyl-sn-glycero-3-PC

1,2-十六烷基卵磷脂
A synthetic ether-linked phospholipid
GC45783 1,2-Dioleoyl-rac-glycerol-13C3 An internal standard for the quantification of 1,2-dioleoyl-rac-glycerol
GC46379 1,2-Dioleoyl-sn-glycero-3-PS (sodium salt)

1,2-二-(9Z-十八碳烯酰基)-sn-甘油-3-磷酰-L-丝氨酸钠盐
A phospholipid
GC41823 1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) (sodium salt)

biotin-cap-DPPE
A biotinylated phospholipid
GC46385 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-Mannopyranose

1,3,4,6-四-O-乙酰基-2-叠氮基-2-脱氧-Α-D-吡喃甘露糖
A ManNAc analog and building block
GC19528 1,4-Benzoquinone

对苯醌
A toxic metabolite of benzene
GC18726 1-Methyl-1,4-dihydronicotinamide A nicotinamide derivative
GC90829 1-Palmitoyl-2-Pyropheophorbide a-sn-glycero-3-PC

1-Palmitoyl-2-Pyropheophorbide a-sn-glycero-3-Phosphocholine, 1-Palmitoyl-2-Pyropheophorbide a-sn-glycero-3-Phosphatidylcholine, Porphyrin-lipid, Pyro-PtdCho

一种磷脂-卟啉共轭物
GC49736 10-acetyl Docetaxel

多西他赛,10-Acetyl docetaxel; PNU-101383
A derivative of paclitaxel and an inhibitor of microtubule depolymerization
GC12954 10-DAB (10-Deacetylbaccatin)

10-脱乙酰巴卡丁 III
An inhibitor of microtubule assembly
GC35044 10-Deacetyl-7-xylosyl paclitaxel

7-木糖甙-10-脱乙酰基紫杉醇,10-Deacetyl-7-xylosyltaxol; 10-Deacetylpaclitaxel 7-Xyloside; 10-Deacetyltaxol 7-Xyloside
A microtubule disruptor
GC35045 10-Oxo Docetaxel

10-羰基多西他赛,Docetaxel Impurity 1
A docetaxel degradation product
GC17295 10058-F4

5-(4-乙基苯亚甲基)
10058-F4是一种c-Myc抑制剂，抑制c-Myc-Max二聚化，阻止c-Myc靶基因表达的转录激活。
GC63576 10074-A4 10074-A4 是一种 c-Myc 结合化合物，与 c-Myc370–409 结合，表现得像“蛋白质云”周围的“配体云”，具有与非结合配体截然不同的特征。具有抗癌作用
GC14918 10074-G5

N-2-联苯基-7-硝基-2,1,3-苯并恶二唑-4-胺
An inhibitor of c-Myc/Max dimerization
GC40448 12(S)-HETE

12(S)-Hydroxyeicosatetraenoic Acid
The predominant lipoxygenase product of mammalian platelets
GC46434 13C15-Nivalenol An internal standard for the quantification of nivalenol
GC49390 13C6-4-Nitroaniline

13C6-p-Nitroaniline
An internal standard for the quantification of 4-nitroaniline