Cell Cycle/Checkpoint(细胞周期/检查点)

Cell Cycle

Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0. read more

Products for Cell Cycle/Checkpoint

Cat.No. 产品名称 Information
GC46446 15-deoxy-δ12,14-Prostaglandin J2-biotin

15deoxyΔ12,14PGJ2biotin
A neuropeptide with diverse biological activities
GC41110 16-epi Latrunculin B

16拉春库林B
An actin depolymerizing macrolide
GC48423 19-O-Acetylchaetoglobosin A

Chaetoglobosin A Acetate
A fungal metabolite with actin polymerization inhibitory and cytotoxic activities
GC42151 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)

dGMP
A natural precursor of dGTP
GC90819 2,3,7,8-Tetrachlorodibenzofuran

PCDF 83, 2,3,7,8-TCDF, TCDF

一种多氯二苯并呋喃和二恶英
GC40947 2,3-Dimethoxy-5-methyl-p-benzoquinone

2,3-二甲氧基-5-甲基-1,4-苯醌,CoQ0
An intermediate in the synthesis of ubiquinones that has anticancer activity
GC45324 2,5-dimethyl Celecoxib

2,5-二甲基塞来考昔
An anticancer celecoxib derivative
GC49362 2-Amino-3,8-dimethylimidazo-[4,5-f]-quinoxaline

2-氨基-3,8-二甲基咪唑并喹喔啉
A food-derived carcinogen
GC52029 2-Aminoflubendazole

2-氨基氟苯咪唑
A metabolite of flubendazole
GC90840 2-Chloroadenosine-5'-O-diphosphate (sodium salt)

2-chloro ADP

ADP的衍生物。
GC40675 2-deoxy-Artemisinin

脱氧青蒿素
An inactive metabolite of artemisinin
GC62777 2-Methoxy-4-vinylphenol

4-乙烯基-2-甲氧基苯酚
2-Methoxy-4-vinylphenol (2M4VP) 是天然的发芽抑制剂，具有抗炎活性。
GC15084 2-Methoxyestradiol (2-MeOE2)

二甲氧基雌二醇; 2-ME2; NSC-659853
2-Methoxyestradiol (2-MeOE2/2-Me)是一种HIF-1α抑制剂。
GC52140 2-Methoxyhydroquinone

2-甲氧基对苯二酚
A phenolic compound
GC91133 2-n-Dodecylfuran
一种合成中间体
GC42161 2H-Cho-Arg (trifluoroacetate salt) A steroid-based cationic lipid
GC40618 3',4',7-Trihydroxyisoflavone

3',4',7-三羟基异黄酮
A natural isoflavone
GC45332 3'-Dephosphocoenzyme A

depCoA, Dephospho-CoA
An intermediate in the biosynthesis of CoA
GC18452 3,4-Dichloroisocoumarin

3,4-DCI

A serine protease inhibitor
GC42239 3,6-diacetoxy Phthalonitrile

1,4-二乙酰基-2,3-二氰苯
A fluorescent pH probe
GC12314 3-(4-Pyridyl)indole

Rho Kinase Inhibitor III,ROCK Inhibitor III,Rockout
A ROCK1 and ROCK2 inhibitor
GC46582 3-Acetyldeoxy Nivalenol-13C17

3-乙酰基呕吐毒素-13C标记
An internal standard for the quantification of 3-acetyldeoxy nivalenol
GC52129 3-Amino-5-hydroxybenzoic Acid

3-氨基-5-羟基苯甲酸
A biosynthetic precursor to ansamycin antibiotics
GC15389 360A

3,3'-[2,6-吡啶二基二(羰基亚氨基)]二[1-甲基喹啉鎓],360 A
360A 是 G-quadruplex 的选择性稳定剂，也抑制端粒酶活性，在 TRAP-G4 试验中对端粒酶的 IC50 为 300 nM。
GC10115 360A iodide

360A碘化物,360 A iodide
360A iodide 是 G-quadruplex 的选择性稳定剂，也抑制端粒酶活性，在 TRAP-G4 试验中对端粒酶的 IC50 为 300 nM。
GC14186 3MB-PP1

4-氨基-1-叔丁基-3-(3-甲基苄基)吡唑并[3,4-D]嘧啶
An inhibitor of analog-sensitive Plk1 alleles
GC45354 4β-Hydroxywithanolide E

4BETA-羟基醉茄内酯E
A withanolide with anti-inflammatory and anticancer activities
GC17271 4'-Demethylepipodophyllotoxin

4'-去甲基表鬼臼毒素; 4'-O-demethylepipodophyllotoxin; 4'-DMEP
An inhibitor of tubulin polymerization
GC46606 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaboran-2yl)aniline

4-氨基苯硼酸频哪醇酯
A heterocyclic building block
GC46635 4-deoxy Nivalenol-13C15

全13C标记的脱氧雪腐镰刀菌烯醇
An internal standard for the quantification of 4-deoxy nivalenol
GC18359 4-Epianhydrochlortetracycline (hydrochloride)

4-差向四环素盐酸盐
An inhibitor of MMP-9
GC42449 4-Methylumbelliferyl-α-L-Iduronide (free acid)

ALPHA-L-四羟基环氧戊酸-4-甲基伞形酯
A fluorogenic substrate for α-L-iduronidase
GC49244 4-oxo Isotretinoin

4-酮13-顺式维甲酸
An active metabolite of isotretinoin
GC52365 4-tert-Octylphenol monoethoxylate

NSC 5259, OP1EO
An alkylphenolethoxylate and a degradation product of non-ionic surfactants
GC46687 5'-Deoxy-5'-methylthioadenosine-d3

5'-S-Methylthioadenosine-d3, MTA-d3, Vitamin L2-d3
An internal standard for the quantification of 5’-deoxy-5’-methylthioadenosine
GC52227 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone

(±)-δ-(3,4-Dihydroxyphenyl)-γ-Valerolactone, 5-(3',4'-Dihydroxyphenyl)-γ-VL
An active metabolite of various polyphenols
GC73301 5-Aminosalicylic acid-d3

Mesalamine-d3; 5-ASA-d3; Mesalazine-d3
5-Aminosalicylic acid-d3是氘标记的5-氨基水杨酸。
GC46681 5-Bromouridine

5-溴尿苷
A brominated uridine analog
GC45357 5-Chlorouracil

5-氯尿嘧啶
A chlorinated derivative of uracil
GC42548 5-hydroxy Saxagliptin (hydrochloride) A major active metabolite of saxagliptin
GC41156 5-Octyl D-glutamate

5-Octyl ester D-glutamatic acid
A cell-permeable form of D-glutamate
GC41423 5-trans Prostaglandin E2

transDinoprostone, 5,6trans PGE2
An impurity in commercial lots of PGE₁
GC42586 6α-hydroxy Paclitaxel

6-羟基泰素
A metabolite of paclitaxel
GC63958 6α-Hydroxy Paclitaxel-d5

紫杉醇杂质
6α-Hydroxy Paclitaxel-d5 是 6α-Hydroxy paclitaxel 的氘代物。6α-Hydroxy paclitaxel 是紫杉醇的初级代谢物。6α-Hydroxy paclitaxel 对有机阴离子转运多肽 1B1/SLCO1B1 (OATP1B1) 具有与紫杉醇相似的时间依赖性抑制效力，但它对 OATP1B3 不具有时间依赖性作用。6α-Hydroxy paclitaxel 可用于癌症研究。
GC45969 6β-hydroxy Eplerenone

依普利酮6-BETA-羟基类似物
A major metabolite of eplerenone
GC72854 6-CEPN 6-CEPN是RAS抑制剂。
GC46721 6-Chloro-2-fluoropurine

2-氟-6-氯嘌呤
A heterocyclic building block
GC48721 6-O-Demethyl Griseofulvin

6-Demethylgriseofulvin
A metabolite of griseofulvin
GC90761 6-PPD-quinone

6-PPDQ
6-PPD-quinone是大麻素受体2（CNR2）的激动剂，对CNR2具有高亲和力。
GC15478 6H05

6H05(6H零5)
An allosteric inhibitor of oncogenic K-Ras(G12C)