Rho

Rho GTPases act as molecular switches that convert and amplify external signals into cellular effects upon activation of cell surface receptor in various signaling transduction pathway. It functions in cell proliferation, motility, survival cytoskeletal remodeling and membrane trafficking etc.

Rho 相关产品(13)

GC10030 EHop-016
CAS: 1380432-32-5
纯度: >99.00%
EHop-016是一种高效的Rac GTP酶Rac1抑制剂，IC 50 值为1.1μM。
GC10069 NSC 23766 trihydrochloride
CAS: 1177865-17-6
纯度: >99.50% / >99.00%
NSC 23766 trihydrochloride是一种选择性Rac1 GTPase抑制剂，通过特异性阻断Rac1的鸟嘌呤核苷酸交换因子Trio和Tiam1来抑制Rac1的激活，对Rac1的IC₅₀约为50μM。
GC12470 ZCL278
CAS: 587841-73-4
纯度: >98.00%
A selective Cdc42 inhibitor
GC10419 (R)-CCG-1423
CAS: 2309931-09-5
A stereoisomer of CCG-1423, a Rho inhibitor
GC11754 AS 1892802
CAS: 928320-12-1
A ROCK1 and ROCK2 inhibitor
GC12795 CCG-1423
CAS: 285986-88-1
纯度: >99.50%
An inhibitor of Rho-mediated cell signalling
GC12817 K-115 hydrochloride dihydrate
CAS: 887375-67-9
纯度: >99.50%
K-115 hydrochloride dihydrate (K-115) 是 ROCK 的特异性抑制剂，对 ROCK2 和 ROCK1 的 IC50 分别为 19 和 51 nM。
GC14497 (S)-CCG-1423
CAS: 2319939-24-5
A stereoisomer of CCG-1423, a Rho inhibitor
GC14986 CCG-100602
CAS: 1207113-88-9
纯度: >99.50%
A Rho/MKL1 transcriptional pathway inhibitor
GC15170 SB 772077B dihydrochloride
CAS: 607373-46-6
纯度: >98.50%
A ROCK1 and ROCK2 inhibitor
GC15478 6H05
CAS: 1469338-01-9
An allosteric inhibitor of oncogenic K-Ras(G12C)
GC14701 Zoledronic Acid
CAS: 118072-93-8
纯度: >98.00% / >99.00%
Zoledronic Acid是一种第三代含氮双膦酸盐类骨吸收抑制剂。
GC17388 K-Ras(G12C) inhibitor 6
CAS: 2060530-16-5
K-Ras(G12C) inhibitor 6 是一种不可逆的 K-Ras(G12C) 变构抑制剂。

分类产品列表
货号	产品名称	CAS号	纯度
GC10030	EHop-016	1380432-32-5	>99.00%
GC10030	EHop-016是一种高效的Rac GTP酶Rac1抑制剂，IC 50 值为1.1μM。
GC10069	NSC 23766 trihydrochloride	1177865-17-6	>99.50% / >99.00%
GC10069	NSC 23766 trihydrochloride是一种选择性Rac1 GTPase抑制剂，通过特异性阻断Rac1的鸟嘌呤核苷酸交换因子Trio和Tiam1来抑制Rac1的激活，对Rac1的IC₅₀约为50μM。
GC12470	ZCL278	587841-73-4	>98.00%
GC12470	A selective Cdc42 inhibitor
GC10419	(R)-CCG-1423	2309931-09-5	-
GC10419	A stereoisomer of CCG-1423, a Rho inhibitor
GC11754	AS 1892802	928320-12-1	-
GC11754	A ROCK1 and ROCK2 inhibitor
GC12795	CCG-1423	285986-88-1	>99.50%
GC12795	An inhibitor of Rho-mediated cell signalling
GC12817	K-115 hydrochloride dihydrate	887375-67-9	>99.50%
GC12817	K-115 hydrochloride dihydrate (K-115) 是 ROCK 的特异性抑制剂，对 ROCK2 和 ROCK1 的 IC50 分别为 19 和 51 nM。
GC14497	(S)-CCG-1423	2319939-24-5	-
GC14497	A stereoisomer of CCG-1423, a Rho inhibitor
GC14986	CCG-100602	1207113-88-9	>99.50%
GC14986	A Rho/MKL1 transcriptional pathway inhibitor
GC15170	SB 772077B dihydrochloride	607373-46-6	>98.50%
GC15170	A ROCK1 and ROCK2 inhibitor
GC15478	6H05	1469338-01-9	-
GC15478	An allosteric inhibitor of oncogenic K-Ras(G12C)
GC14701	Zoledronic Acid	118072-93-8	>98.00% / >99.00%
GC14701	Zoledronic Acid是一种第三代含氮双膦酸盐类骨吸收抑制剂。
GC17388	K-Ras(G12C) inhibitor 6	2060530-16-5	-
GC17388	K-Ras(G12C) inhibitor 6 是一种不可逆的 K-Ras(G12C) 变构抑制剂。