CRM1

CRM1(染色体维持蛋白1)

CRM1 (i.e. XPO-1, Exportin-1) is a mammalian ubiquitous protein that mediates the transport of protein and RNA across the nuclear membrane to the cytoplasm.

CRM1 相关产品(8)

  • GC12142 structure
    GC12142KPT-276
    CAS: 1421919-75-6

    An inhibitor of XPO1/CRM1

  • GC12467 structure
    GC12467KPT-330
    CAS: 1393477-72-9
    纯度: >98.00%

    KPT-330(Selinexor)是一种具有口服活性的选择性核输出抑制剂(SINE)化合物,抑制核输出蛋白XPO1(又名CRM1)。

  • GC14517 structure
    GC14517KPT-185
    CAS: 1333151-73-7

    An inhibitor of XPO1/CRM1

  • GC10954 structure
    GC10954Leptomycin B
    CAS: 87081-35-4
    纯度: >99.50%

    Leptomycin B (LMB)是染色体区域维持1 (CRM1)的抑制剂,CRM1是核蛋白输出蛋白之一。

  • GC15777 structure
    GC15777Verdinexor (KPT-335)
    CAS: 1392136-43-4

    An inhibitor of XPO1

  • GC18345 structure
    GC18345Leptomycin A
    CAS: 87081-36-5

    An inhibitor of nuclear transport

  • GC19213 structure
    GC19213Eltanexor Z-isomer
    CAS: 1642300-78-4

    Eltanexor Z-异构体(KPT-8602 Z-异构体)是 KPT-8602 活性较低的异构体。

  • GC19466 structure
    GC19466Eltanexor (KPT-8602)
    CAS: 1642300-52-4
    纯度: >98.00% / >99.50%

    Eltanexor (KPT-8602)是一种口服有效的输出蛋白-1(XPO1)抑制剂(EC 50 = 60.9nM)。