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Home >> Signaling Pathways >> Neuroscience >> Muscarinic Receptor

Muscarinic Receptor(毒蕈碱受体)

Muscarinic receptor is a group of G-protein coupled receptors that binds to acetylcholine and mediates cellular responses, including inhibition of acetylate cyclase, phosphoinositide degradation and regulation of potassium channels. It is involved in the neurological diseases such as Alzheimer's and Parkinson's.

Products for  Muscarinic Receptor

  1. Cat.No. 产品名称 Information
  2. GC10736 (+)-Muscarine iodide

    (+)-Muscarine iodide

     毒蕈碱 ((+)-Muscarine) 碘化物是一种可以刺激副交感神经系统的毒素。
  3. GC14479 (S)-(+)-Dimethindene maleate (S)-(+)-Dimethindene maleate 是一种对映异构体，是一种有效的 M2 选择性毒蕈碱受体拮抗剂 (pA2 =7.86/7.74; pKi =7.78)。
  4. GC13348 4-DAMP

    4-二苯乙酰氧基-N-甲基-哌啶甲碘化物,4-DAMP methiodide

     An antagonist of the muscarinic M3 receptor
  5. GC14604 5-Methylfurmethiodide

    5-甲呋硫碘

     muscarinic agonist
  6. GC12787 Aceclidine (hydrochloride)

    羟甲基-7-氨基头孢烷酸

     A muscarinic receptor agonist
  7. GC14096 Aclidinium Bromide

    阿地溴铵; LAS 34273; LAS-W 330

     A muscarinic acetylcholine receptor antagonist
  8. GC10219 AF-DX 116

    11-((2-((二乙氨基)甲基)-1-哌啶基)乙酰基)-5,11-二氢-(6H)-吡啶并[2.3-B][1.4]苯并二氮杂-6-酮,AF-DX 116

     A muscarinic M2 receptor antagonist
  9. GC15510 AF-DX 384 An M2 and M4 muscarinic acetylcholine receptor antagonist
  10. GC13340 AQ-RA 741 M2 antagonist,selective and high affinity
  11. GC11415 Arecaidine but-2-ynyl ester tosylate mAChR M2 激动剂
  12. GC16504 Arecaidine propargyl ester tosylate muscarinic receptor agonist
  13. GC10621 Biperiden HCl

    盐酸比哌立登; KL 373 hydrochloride

    A muscarinic acetylcholine receptor antagonist
  14. GC15758 BQCA

    1-(4-甲氧基苄基)-4-氧代-1,4-二氢喹啉-3-羧酸

     A positive allosteric modulator of the M1 mAChR
  15. GC14215 Cevimeline

    西维美林; AF102B

     A muscarinic receptor agonist
  16. GC17157 Cevimeline hydrochloride hemihydrate

    盐酸西维美林半水合物; SNI-2011; AF102B hydrochloride hemihydrate

     Cevimeline hydrochloride hemihydrate (SNI-2011) 是乙酰胆碱的奎宁环衍生物，是一种选择性和口服活性的毒蕈碱 M1 和 M3 受体激动剂。
  17. GC15772 Darifenacin HBr

    氢溴酸达非那新; UK-88525 hydrobromide

     A muscarinic M3 receptor antagonist
  18. GC10633 DAU 5884 hydrochloride muscarinic M3 receptor antagonist
  19. GC16087 Fesoterodine Fumarate

    富马酸非索罗定

     A muscarinic acetylcholine receptor antagonist
  20. GC15845 Guvacoline (hydrobromide)

    氢溴酸胍喹啉,Norarecoline

     A muscarinic receptor agonist
  21. GC12056 J 104129 fumarate M3 muscarinic receptor antagonist
  22. GC16458 McN-A 343

    4-[N-(3-氯苯基)氨基甲酰氧]-2-丁炔基三甲基氯化铵

     A partial agonist of muscarinic acetylcholine receptors
  23. GC14619 Milameline hydrochloride Muscarinic receptor agonist
  24. GC10378 N-Isopropylnoratropine

    异丙托品杂质E,NINA

     An intermediate in the synthesis of ipratropium
  25. GC10525 Nitrocaramiphen hydrochloride M1 muscarinic antagonist
  26. GC16463 Oxotremorine M

    碘化氧化震颤素M

     A muscarinic receptor agonist and KCNQ2/3 potassium channel blocker
  27. GC16156 Oxotremorine sesquifumarate

    1-(4-[1-吡咯烷基]-2-丁炔基)-2-吡咯烷酮

     A muscarinic acetylcholine receptor agonist
  28. GC17876 PD 102807 PD 102807 是一种 M4 毒蕈碱受体拮抗剂，IC50 为 90.7 nM。
  29. GC13403 Pirenzepine dihydrochloride

    盐酸哌仑西平,LS 519; Pirenzepin dihydrochloride; Gastrozepin dihydrochloride

     A muscarinic M1 receptor antagonist
  30. GC14508 PTAC oxalate muscarinic receptor ligand
  31. GC17182 Solifenacin succinate

    索非那新琥珀酸盐; YM905

     A muscarinic M1, M2, and M3 receptor antagonist
  32. GC13174 Telenzepine dihydrochloride

    替仑西平二盐酸盐；太兰泽平二盐酸盐

     Telenzepine dihydrochloride 是一种选择性和口服活性的毒蕈碱 M1 受体拮抗剂，Ki 为 0.94 nM。
  33. GC17954 Tolterodine tartrate

    酒石酸托特罗定,Kabi-2234; PNU-200583E

     A muscarinic acetylcholine receptor antagonist
  34. GC12311 Trihexyphenidyl hydrochloride

    盐酸苯海索

     A muscarinic M1 receptor antagonist
  35. GC11831 Umeclidinium bromide

    芜地溴铵; GSK573719A

     A muscarinic acetylcholine receptor antagonist
  36. GC15990 VU 0238429

    HY-12157, ML129

     A muscarinic M5 receptor positive allosteric modulator
  37. GC10464 VU 0255035

    N-(3-氧代-3-(4-(吡啶-4-基)哌嗪-1-基)丙基)苯并[C][1,2,5]噻二唑-4-磺酰胺,VU 255035

     A selective muscarinic M1 receptor antagonist
  38. GC16655 VU 0357017 hydrochloride

    CID-25010775

     An M1 muscarinic acetylcholine receptor agonist
  39. GC17821 VU 0365114 A positive allosteric modulator of muscarinic M5 receptors
  40. GC10725 VU 10010 VU 10010 是一种有效的、高选择性的变构 M4 mAChR 增强剂，EC50 为 400 nM。
  41. GC13129 W-84 dibromide

    HDMPPA

     W-84 (dibromide) 是一种有效的 M2-胆碱受体变构调节剂，可延缓 [3H]N-甲基东莨菪碱的解离。
  42. GC18082 Zamifenacin fumarate

    扎非那星富马酸盐; UK-76654 fumarate

     A muscarinic M3 receptor antagonist

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