Muscarinic Receptor
Muscarinic Receptor(毒蕈碱受体)
Muscarinic receptor is a group of G-protein coupled receptors that binds to acetylcholine and mediates cellular responses, including inhibition of acetylate cyclase, phosphoinositide degradation and regulation of potassium channels. It is involved in the neurological diseases such as Alzheimer's and Parkinson's.
Muscarinic Receptor 相关产品(41)
- GC13403Pirenzepine dihydrochlorideCAS: 29868-97-1纯度: >99.00% / >98.00%
A muscarinic M 1 receptor antagonist
- GC14479(S)-(+)-Dimethindene maleateCAS: 136152-65-3纯度: >98.50% / >99.50%
(S)-(+)-Dimethindene maleate是一种具有高效选择性的毒蕈碱M2受体拮抗剂（pA2 = 7.86/7.74; pK i = 7.78）。
- GC15990VU 0238429CAS: 1160247-92-6纯度: >99.50%
A muscarinic M 5 receptor positive allosteric modulator
- GC16156Oxotremorine sesquifumarateCAS: 17360-35-9纯度: >98.00%
A muscarinic acetylcholine receptor agonist
- GC16463Oxotremorine MCAS: 3854-04-4纯度: >99.50%
A muscarinic receptor agonist and KCNQ2/3 potassium channel blocker
- GC16655VU 0357017 hydrochlorideCAS: 1135242-13-5纯度: >99.00%
An M 1 muscarinic acetylcholine receptor agonist
- GC17821VU 0365114CAS: 1208222-39-2纯度: >99.50%
A positive allosteric modulator of muscarinic M 5 receptors
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC13403 | Pirenzepine dihydrochloride | 29868-97-1 | >99.00% / >98.00% | |
A muscarinic M 1 receptor antagonist | ||||
| GC14479 | (S)-(+)-Dimethindene maleate | 136152-65-3 | >98.50% / >99.50% | |
(S)-(+)-Dimethindene maleate是一种具有高效选择性的毒蕈碱M2受体拮抗剂（pA2 = 7.86/7.74; pK i = 7.78）。 | ||||
| GC14508 | PTAC oxalate | 201939-40-4 | - | |
muscarinic receptor ligand | ||||
| GC14604 | 5-Methylfurmethiodide | 1197-60-0 | - | |
muscarinic agonist | ||||
| GC14619 | Milameline hydrochloride | 139886-04-7 | - | |
Muscarinic receptor agonist | ||||
| GC15510 | AF-DX 384 | 118290-26-9 | >95.00% | |
An M 2 and M 4 muscarinic acetylcholine receptor antagonist | ||||
| GC15758 | BQCA | 338747-41-4 | >98.50% | |
A positive allosteric modulator of the M 1 mAChR | ||||
| GC15845 | Guvacoline (hydrobromide) | 17210-51-4 | - | |
A muscarinic receptor agonist | ||||
| GC15990 | VU 0238429 | 1160247-92-6 | >99.50% | |
A muscarinic M 5 receptor positive allosteric modulator | ||||
| GC16156 | Oxotremorine sesquifumarate | 17360-35-9 | >98.00% | |
A muscarinic acetylcholine receptor agonist | ||||
| GC16458 | McN-A 343 | 55-45-8 | >99.50% | |
A partial agonist of muscarinic acetylcholine receptors | ||||
| GC16463 | Oxotremorine M | 3854-04-4 | >99.50% | |
A muscarinic receptor agonist and KCNQ2/3 potassium channel blocker | ||||
| GC16504 | Arecaidine propargyl ester tosylate | 147202-94-6 | - | |
muscarinic receptor agonist | ||||
| GC16655 | VU 0357017 hydrochloride | 1135242-13-5 | >99.00% | |
An M 1 muscarinic acetylcholine receptor agonist | ||||
| GC17821 | VU 0365114 | 1208222-39-2 | >99.50% | |
A positive allosteric modulator of muscarinic M 5 receptors | ||||
| GC17876 | PD 102807 | 23062-91-1 | - | |
PD 102807 是一种 M4 毒蕈碱受体拮抗剂，IC50 为 90.7 nM。 | ||||
| GC18082 | Zamifenacin fumarate | 127308-98-9 | >99.50% | |
A muscarinic M 3 receptor antagonist | ||||