GlpBio

CTP354

目录号: GC52077纯度: >99.00%
A deuterated derivative of L-838,417
CTP354
Cas No.: 1213669-91-0
规格价格库存数量操作
5 mg¥984.00现货
1
10 mg¥1,872.00现货
1
25 mg¥3,696.00现货
1
50 mg¥6,392.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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    641, 529–536 (2025)
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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

产品描述 Description

CTP354 is a deuterated derivative of the GABAA receptor modulator L-838,417.1 It binds to the GABAA receptor benzodiazepine binding site in non-α1 subunit-containing GABAA receptors. CTP354 has a longer duration of action than L-838,417 in a rat model of neuropathic pain induced by sciatic nerve ligation.

1.Harbeson, S.L., and Tung, R.D.Deuterium medicinal chemistry: A new approach to drug discovery and developmentMedchem News24(2)8-22(2014)

产品文档 Product Documents

Purity:>99.00%Appearance:A solid

化学性质Chemical Properties

CAS 号
1213669-91-0
SMILES
CN1C(COC2=NN3C(C4=C(C=CC(F)=C4)F)=NN=C3C=C2C(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=NC=N1
分子式
C19H10D9F2N7O
分子量
408.5 g/mol
溶解性
DMF: 3 mg/ml,DMSO: 3 mg/ml,Ethanol: 2 mg/ml,PBS (pH 7.2): insol
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol