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Home >> Signaling Pathways >> Neuroscience

Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for  Neuroscience

  1. Cat.No. 产品名称 Information
  2. GC42692 Aceclofenac methyl ester

    Aceclofenac Impurity D

     A potential impurity in commercial preparations of aceclofenac
  3. GC10454 Acemetacin

    阿西美辛; TVX 1322

     An NSAID
  4. GC15203 Acephate

    乙酰甲胺磷

     An organophosphate insecticide
  5. GC45371 Acepromazine (maleate)

    乙酰丙嗪马来酸酯,Acetopromazine maleate; Acetylpromazine maleate

     A phenothiazine antipsychotic
  6. GC12917 Acetaminophen

    对乙酰氨基酚; Paracetamol; 4-Acetamidophenol; 4'-Hydroxyacetanilide

    An analgesic and antipyretic compound
  7. GC42693 Acetaminophen Glucuronide (sodium salt)

    P-乙酰氨基苯-B-D-葡萄糖酸钠盐

     An inactive metabolite of acetaminophen
  8. GC42694 Acetaminophen sulfate (potassium salt)

    4-乙酰氨基酚硫酸钾盐

     An inactive metabolite of acetaminophen
  9. GC64137 Acetaminophen-d3

    扑热息痛D3,Paracetamol-d3; 4-Acetamidophenol-d3; 4'-Hydroxyacetanilide-d3

     Acetaminophen-d3 (Paracetamol-d3) 是 Acetaminophen 的氘代物。Acetaminophen (Paracetamol) 是选择性环氧合酶-2 (COX-2) 的抑制剂，IC50 值为 25.8 μM。Acetaminophen 是一种有效的肝 N-乙酰转移酶 2 (NAT2) 抑制剂。Acetaminophen 是广泛使用的解热和止痛剂。
  10. GC46781 Acetaminophen-d4

    对乙酰氨基酚 d4

     An internal standard for the quantification of acetaminophen
  11. GC18262 Acetamiprid

    啶虫脒

     A neonicotinoid insecticide
  12. GC42703 Acetyl β-Endorphin (1-26) (human) (trifluoroacetate salt) A neuropeptide
  13. GC42704 Acetyl β-Endorphin (human) (trifluoroacetate salt)

    N-acetyl β-endorphin

     An acetylated derivative of β-endorphin
  14. GC46789 Acetyl-L-carnitine-d3 (chloride)

    O-Acetyl-L-carnitine-d3-1 hydrochloride

     An internal standard for the quantification of L-acetylcarnitine
  15. GC40952 Acetylaszonalenin

    LL-S490β

     A fungal metabolite
  16. GC14142 Acetylcholine Chloride

    氯化乙酰胆碱; ACh chloride

     A neurotransmitter
  17. GC68602 Acetylcholine-d13 bromide

    ACh-d13 (bromide)

     Acetylcholine-d13 (bromide) 是 Acetylcholine bromide 的氘代物。
  18. GC11786 Acetylcysteine

    乙酰半胱氨酸; N-Acetylcysteine; N-Acetyl-L-cysteine; NAC

     乙酰半胱氨酸是半胱氨酸的 N-乙酰基衍生物。
  19. GC35236 Acetylshikonin

    乙酰紫草素

     Acetylshikonin，来源于紫草根，具有抗癌、抗炎作用。Acetylshikonin 是一种非选择性的细胞色素 P450 抑制剂，对所有 P450 亚型抑制的 IC50 值范围为 1.4-4.0 μM。Acetylshikonin 是一种 AChE 抑制剂，具有很强的抗凋亡活性。
  20. GC65618 AChE-IN-23 AChE-IN-23 (compound 3h) 是一种乙酰胆碱酯酶 (AChE) 抑制剂，其 IC50 值为 48.3 μM。
  21. GC68609 AChE-IN-26 AChE-IN-26 (compound 4a) 是 AChE (acetylcholinesterase) 的抑制剂，IC50 值为 0.42 μM。AChE-IN-26 可用于阿尔兹海默症的研究。
  22. GC65979 AChE-IN-27 AChE-IN-27 (化合物 8c) 是一种 AChE 抑制剂 (IC50=0.19 µM)。AChE-IN-27 可用于神经系统疾病，如阿尔茨海默病、老年痴呆、共济失调和重症肌无力得研究。
  23. GC64390 AChE-IN-3 AChE-IN-3 对 AChE 有中度抑制活性，对 NO 有较强抑制活性，其 EC50 为 0.57 μM。
  24. GC68608 AChE/BChE-IN-10 AChE/BChE-IN-10 (Compound 7b) 是一种有效的 AChE 和 BChE 双重抑制剂，IC50 值分别为 0.176 和 0.47 μM。AChE/BChE-IN-10 显示出良好的血脑屏障渗透性。AChE/BChE-IN-10 可以抑制 Aβ 的聚集，可用于阿尔茨海默病的研究。
  25. GC70960 AChE/BChE/MAO-B-IN-1 AChE/BChE/MAO-B-IN-1（化合物10）是一种可逆且非时间依赖性的AChE、BChE和MAO-B抑制剂，hAChE，hBChE，hMAO-B的IC50值分别为7.31、0.56和26.1μM。
  26. GC14096 Aclidinium Bromide

    阿地溴铵; LAS 34273; LAS-W 330

     A muscarinic acetylcholine receptor antagonist
  27. GC62827 Acotiamide D6

    Z-338-d6 free base; YM443-d6 free base

     Acotiamide D6 是 Acotiamide 的氘代物。Acotiamide 是有潜力用于功能性消化不良的首创的且具有口服活性的胃肠动力药。
  28. GC38732 Acotiamide monohydrochloride trihydrate

    盐酸阿考替胺三水合物

     Acotiamide Hydrochloride (YM-443, Z-338) is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. It is a new orally active selective acetylcholinesterase inhibitor.
  29. GC12435 ACPT-I An mGluR4a and mGluR8 agonist
  30. GC31695 Acrivastine (BW825C)

    阿伐斯汀; BW825C

     A histamine H1 receptor antagonist
  31. GC60563 Acrivastine D7

    阿伐斯汀-D7,BW825C D7

     AcrivastineD7(BW825CD7)是Acrivastine的一种氘代化合物。Acrivastine是一种短效的histamine1受体拮抗剂。
  32. GC40645 Actarit

    阿克他利,4-Acetylaminophenylacetic acid; MS-932

     An anti-inflammatory agent
  33. GC42713 ACTH (1-10) (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)

    Adrenocorticotropic Hormone (1-10), Corticotropin (1-10)

     A peptide fragment of ACTH
  34. GC45372 ACTH (1-13) (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)

    SYSMEHFRWGKPV-OH

     A peptide fragment of ACTH
  35. GC45373 ACTH (1-16) (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)

    Adrenocorticotropic Hormone (1-16), SYSMEHFRWGKPVGKK-OH

     A peptide fragment of ACTH
  36. GC45375 ACTH (1-39) (trifluoroacetate salt)

    Adrenocorticotropic Hormone (1-39)

     A MC2R agonist
  37. GC40161 ACTH (4-10) (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)

    Adrenocorticotropic Hormone (4-10), Corticotropin (4-10)

     An endogenous peptide fragment of ACTH
  38. GC40132 ACTH (6-24) (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)

    HFRWGKPVGKKRRPVKVYP

     A peptide fragment of ACTH
  39. GC15141 ACV 1 Neuronal nicotinic receptor antagonist
  40. GC31693 Adelmidrol

    阿地米屈

     Adelmidrol is an analogue of palmitoylethanolamide (PEA) with anti-inflammatory activities.
  41. GC46083 Adenylosuccinic Acid

    腺苷酸基琥珀酸,Aspartyl Adenylate

    腺苷琥珀酸是一种嘌呤核苷酸，也是嘌呤核苷酸循环中的中间产物
  42. GC13542 Adiphenine HCl

    盐酸阿地芬宁

     An anticholinergic agent
  43. GC49216 ADL 08-0011 (hydrochloride)

    阿维莫潘代谢物(ADL08-0011)盐酸盐

     An active metabolite of alvimopan
  44. GC35252 Adoprazine

    阿哆嗪; SLV313

     Adoprazine是5-HT1A受体的完全激动剂和D2/3受体的拮抗剂。
  45. GC42739 Adrenomedullin (1-50) amide (rat) (trifluoroacetate salt) A peptide hormone
  46. GC34230 Adrenomedullin (1-50), rat Adrenomedullin(1-50),rat是由50个氨基酸组成的多肽，能够通过激活CGRP1受体来诱导动脉血管舒张。
  47. GC46807 Adrenomedullin (1-52) (porcine) (trifluoroacetate salt)

    YRQSMNNFQGLRSFGCRFGTCTVQKLAHQIYQFTDKDKDGVAPRSKISPQGY-NH2 (Cys16 and 21 bridge)

     A neuropeptide with diverse biological activities
  48. GC35256 Adrenomedullin (11-50), rat A truncated form of rat adrenomedullin
  49. GC42741 Adrenomedullin (22-52) (human) (trifluoroacetate salt) A C-terminal fragment of adrenomedullin
  50. GC32615 Adrenomedullin (AM) (22-52), human (22-52-Adrenomedullin (human))

    肾上腺髓质素(22-52)(人体),22-52-Adrenomedullin (human)

     Adrenomedullin (AM) (22-52), human是一种NH2末端截断形式的Adrenomedullin (AM)，不具有六元环结构，也不保有降血压和血管舒张活性。
  51. GP10109 Adrenorphin

    H2N-Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-amide

    Adrenorphin 是一种阿片样物质八肽，作为 μ-阿片样物质受体的有效激动剂，Ki 为 12 nM。

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