Etiocholanedione is a neurosteroid.1 It inhibits glycine-induced chloride currents (IGly) in isolated rat hippocampal pyramidal neurons when used at a concentration of 50 µM. Etiocholanedione (0.1, 0.3, and 0.5 mM) also inhibits glucose exchange transport in isolated human erythrocytes.2
1.Bukanova, J.V., SoIntserva, I., and Kudova, E.Neurosteroids as selective inhibitors of glycine receptor activity: Structure-activity relationship study on endogenous androstanes and androstenesFront. Mol. Neurosci.1344(2020) 2.Lacko, L., Wittke, B., and Geck, P.Interaction of steroids with the transport system of glucose in human erythrocytesJ. Cell. Physiol.86 Suppl 2(3 Pt 2)673-680(1975)