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Home >> Signaling Pathways >> Neuroscience

Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for  Neuroscience

  1. Cat.No. 产品名称 Information
  2. GC30983 alpha-Asarone (α-Asarone)

    α-细辛脑; α-Asarone; trans-Asarone

     An inhibitor of HMG-CoA reductase and CYP450 isoforms
  3. GC49199 Alpidem

    阿尔吡登,Ananxyl

     An anxiolytic agent
  4. GC32905 Alprenolol ((RS)-Alprenolol)

    阿普洛尔; (RS)-Alprenolol; dl-Alprenolol

     A non-selective β-AR and 5-HT receptor antagonist
  5. GC14105 Alprenolol hydrochloride

    盐酸阿普洛尔; (RS)-Alprenolol hydrochloride; dl-Alprenolol hydrochloride

     A non-selective β-AR and 5-HT receptor antagonist
  6. GC40024 Altenusin

    细格菌素,Alutenusin

     A fungal metabolite with diverse biological activities
  7. GC30996 Alvameline (Lu 25-109)

    Lu 25-109

     Alvameline (Lu 25-109) (Lu25-109) 是一种部分 M1 激动剂和 M2/M3 拮抗剂。
  8. GC10891 Alverine Citrate

    枸橼酸阿尔维林,NSC 35459

     An antispasmodic agent
  9. GC48529 Alvimopan-d5

    ADL 8-2698-d5

     An internal standard for the quantification of alvimopan
  10. GC49262 Alytesin (trifluoroacetate salt) A neuropeptide with diverse biological activities
  11. GC62834 ALZ-801

    ALZ-801

     ALZ-801 是一种有效的口服小分子 β-淀粉样蛋白 (Aβ) 抗寡聚体和聚集抑制剂，与母体化合物相比，具有显着改善的 PK 特性和胃肠道耐受性的曲米酸的缬氨酸结合前药。
  12. GC10105 Amantadine HCl

    盐酸金刚烷胺; 1-Adamantanamine hydrochloride; 1-Adamantylamine hydrochloride; 1-Aminoadamantane hydrochloride

     An NMDA receptor antagonist and antiviral agent
  13. GC16974 Ambenonium dichloride

    安贝氯铵,WIN 8077 chloride

     Ambenonium (WIN 8077) chloride 是一种具有高亲和力的具有口服活性且可逆的乙酰胆碱酯酶 (AChE) 抑制剂。
  14. GC17184 Ambrisentan

    安倍生坦; BSF 208075; LU 208075

     An ETA receptor antagonist
  15. GC31815 Ambutonium bromide (BL700)

    BL700

     Ambutonium bromide (BL700) 是一种乙酰胆碱拮抗剂。
  16. GC14740 Amfenac Sodium Monohydrate

    氨芬酸钠水合物

     A COX inhibitor and the active metabolite of nepafenac
  17. GC16049 AMI-193

    螺哌丙苯,AMI-193

     AMI-193 (AMI-193) 是一种有效的、选择性的 5-HT2 和多巴胺 D2 受体拮抗剂，Kis 分别为 2 nM 和 3 nM。
  18. GC34064 Aminooxyacetic acid hemihydrochloride (Carboxymethoxylamine Hemihydrochloride)

    氨氧基乙酸半盐酸盐; Carboxymethoxylamine hemihydrochloride; Aminooxyacetate hemihydrochloride

     A GABA-T inhibitor
  19. GC16052 Aminopotentidine H2 antagonist
  20. GC12610 Amisulpride

    氨磺必利; DAN 2163

     A dopamine D2 and D3 and 5-HT2B, 5-HT7, and 5-HT7A receptor antagonist
  21. GC35323 Amisulpride hydrochloride

    氨磺必利盐酸盐; DAN 2163 hydrochloride

     A dopamine D2 and D3 and 5-HT2B, 5-HT7, and 5-HT7A receptor antagonist
  22. GC52004 Amisulpride N-oxide

    氨磺必利杂质11

     A degradation product of amisulpride
  23. GC46843 Amisulpride-d5

    氨磺必利 d5

     An internal standard for the quantification of amisulpride
  24. GC30981 Amitifadine hydrochloride (DOV-21947 hydrochloride)

    DOV-21947 hydrochloride; EB-1010 hydrochloride

    Amitifadine hydrochloride (DOV-21947 hydrochloride) 是一种 5-羟色胺-去甲肾上腺素-多巴胺再摄取抑制剂 (SNDRI)，在 HEK 293 细胞中对 5-羟色胺、去甲肾上腺素和多巴胺的 IC50 分别为 12、23、96 nM。
  25. GC33983 Amitraz (BTS-27419)

    双甲脒; BTS-27419

     A formamidine acaricide
  26. GC25060 Amitriptyline

    MK-230, N-750, Ro41575

     Amitriptyline (MK-230, N-750, Ro41575) is a tricyclic antidepressant (TCA) with analgesic properties, widely used to treat depression and neuropathic pain. Amitriptyline is an inhibitor of both serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki of 3.45 nM and 13.3 nM, respectively. Amitriptyline also inhibits histamine receptor H1, histamine receptor H4, 5-HT2 and sigma 1 receptor with Ki of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively. This product is a waxy solid.
  27. GC13723 Amitriptyline HCl

    盐酸阿米替林

     A tricyclic antidepressant
  28. GC49336 AMK (hydrochloride)

    N-γ-acetyl-5-Methoxykynurenamine, N1-acetyl-5-Methoxykynuramine

     An active metabolite of melatonin
  29. GC11287 AMN 082 dihydrochloride An allosteric mGluR7 agonist
  30. GC70946 AMPA receptor antagonist-3 AMPA receptor antagonist-3是一种AMPA受体拮抗剂，从专利US20070027143A1中提取。
  31. GC70348 AMPA receptor modulator-1 AMPA receptor modulator-1是一种强效、口服活性和选择性AMPAR调节蛋白TARPγ-8阴性调节剂，pIC50为9.7，比GluA1/γ-2更具选择性（pIC50=5）。
  32. GC62840 AMPA receptor modulator-2 AMPA receptor modulator-2 (Example 134) 是 AMPA 受体的调节剂，对TARPγ2 依赖的AMPA 受体的 pIC50 值为 10.1。
  33. GC68438 AMPA receptor modulator-3 AMPA receptor modulator-3 是一种变构的 AMPA 受体调节剂 (EC50: 4.4 μM)。AMPA receptor modulator-3 可用于哺乳动物神经系统的研究，如学习和记忆能力。
  34. GC13164 Ampalex

    安帕来斯; BDP 12

     An AMPA receptor modulator
  35. GC70513 Amperozide Amperozide是一种非典型抗精神病药，其Ki值为26nM，充当5-HT2受体的拮抗剂。
  36. GC14104 Ampiroxicam

    安吡昔康; CP 65703

     A prodrug of piroxicam
  37. GC70271 Ampreloxetine hydrochloride Ampreloxetine hydrochloride是去甲肾上腺素转运蛋白（NET）和血清素5-HT摄取转运蛋白（SERT）的口服活性和中枢神经系统渗透抑制剂，但不是多巴胺转运蛋白（DAT）。
  38. GC33484 Ampyrone (4-Aminoantipyrine)

    4-氨基安替比林

     4-Aminoantipyrine(Ampyrone) is a metabolite of aminopyrine with analgesic, anti-inflammatory, and antipyretic properties. It is used as a reagent for biochemical reactions producing peroxides or phenols.
  39. GC12472 Amthamine dihydrobromide A histamine H2 receptor agonist
  40. GC42793 Amylin (1-13) (human, mouse, rat), (trifluoroacetate salt)

    IAPP (1-13) (human, mouse rat), Islet Amyloid Polypeptide (1-13) (human. mouse, rat)

     A peptide fragment of amylin
  41. GC42794 Amylin (8-37) (human) (trifluoroacetate salt)

    IAPP (8-37) (human), Islet Amyloid Polypeptide (8-37) (human)

     A peptide fragment of amylin
  42. GC42795 Amylin (human) (amidated) (trifluoroacetate salt)

    IAPP (human) (amidated), Islet Amyloid Polypeptide (human) (amidated)

     A peptide hormone
  43. GC42796 Amylin (human) (trifluoroacetate salt)

    IAPP (human), Islet Amyloid Polypeptide (human)

     An antidiabetic peptide that forms amyloid fibrils
  44. GC35334 Amyloid β Peptide (42-1)(human)

    淀粉Β-蛋白(42-1),Amyloid β Peptide (42-1)(human)

     淀粉样蛋白 β Peptide (42-1)(human) 是淀粉样蛋白 β 的无活性形式；肽 (1-42)。
  45. GA20733 Amyloid β-Protein (1-42)

    大豆肽

     与内盐相比，Aβ42 的盐酸盐在 pH 7.4 时更容易聚集。
  46. GA20736 Amyloid β-Protein (1-43)

    淀粉Β-蛋白(1-43)

     淀粉样蛋白 β-Protein (1-43) 比久负盛名的 Aβ1-42 更容易聚集并具有更高的毒性。
  47. GP10099 amyloid A protein fragment [Homo sapiens]

    H2N-Ala-Gly-Leu-Pro-Glu-Lys-Tyr-OH

    Apolipoproteins related to HDL in plasma
  48. GP10118 Amyloid Beta-Peptide (1-40) (human)

    BETA淀粉样蛋白片段1-40,Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val

    Amyloid Beta-Peptide (1-40) (human)是老年斑淀粉样蛋白的主要成分，作为生理性肽段存在于脑组织、脑脊液（CSF）及血浆中。
  49. GP10049 Amyloid Beta-Peptide (12-28) (human)

    淀粉-Β-蛋白片段12-28,Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys

    Amyloid Beta-Peptide (12-28)（人）是 Amyloid Beta 蛋白 (1-42) (Aβ (1-42)) 的肽片段。
  50. GP10082 Amyloid Beta-peptide (25-35) (human)

    BETA-淀粉样蛋白片断25-35,Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met

    淀粉样蛋白β肽(Aβ) (25-35)(human)是阿尔茨海默病淀粉样蛋白β肽的片段，具有神经毒性作用。
  51. GC33160 amyloid P-IN-1 amyloidP-IN-1有利于在疾病或功能失调的治疗中消耗血清淀粉样蛋白P组件(SAP)，包括淀粉样变,阿尔茨海默病，2型糖尿病和关节炎。

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