Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for Neuroscience

Cat.No. 产品名称 Information
GC11309 ARN2966

2-PMAP
An inhibitor of APP production and Aβ secretion
GC17525 AS 19
A 5-HT₇ receptor agonist
GC17776 Asaraldehyde

细辛醛; Asaronaldehyde; Asaraldehyde; 2,4,5-trimethoxy-Benzaldehyde
Asarylaldehyde (Asaronaldehyde) 是一种 COX-2 抑制剂，可显着抑制环氧合酶 II (COX-2) 的活性，IC50 值为 100 μg/mL。
GC11824 Asenapine

阿塞那平; Org 5222
An atypical antipsychotic
GC14518 Asenapine hydrochloride

阿塞那平盐酸盐
Asenapine hydrochloride 是一种抗精神病药，是一种 5-HT (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) 和多巴胺 (D2, D3, D4) 受体拮抗剂，Ki 值为 0.03-4.0 nM，作用 5- HT 和多巴胺受体分别为 1.3、0.42、1.1 nM。
GC63819 Asenapine maleate

阿塞那平马来酸盐; Org 5222 maleate
Asenapine maleate (Org 5222) is a high-affinity antagonist of serotonin, norepinephrine, dopamine and histamine receptors, used for the treatment of schizophrenia and acute mania associated with bipolar disorder.
GC15438 Asoxime (chloride)

HI-6
An AChE reactivator
GC40848 Aspalatone

Acetylsalicylic Acid Matol ester
An antithrombic compound
GC45387 Aspergillimide

(rel)-Aspergillimide; (rel)-VM55598
A fungal metabolite
GC15706 Aspirin (Acetylsalicylic acid)

阿司匹林; Acetylsalicylic Acid; ASA
A non-selective, irreversible COX inhibitor
GC63683 Aspirin-d3

乙酰水杨酸-D3,Acetylsalicylic Acid-d3; ASA-d3
Aspirin-d3 (Acetylsalicylic Acid-d3) 是 Aspirin 的氘代物。Aspirin是非选择性和不可逆的 COX-1 和 COX-2 抑制剂，IC50 分别为5，210 μg/mL。
GC42859 Aspirin-d4

阿司匹林D4,Acetylsalicylic Acid-d4; ASA-d4
An internal standard for the quantification of aspirin
GC16945 Astemizole

阿司咪唑; R 43512
A histamine H1 receptor antagonist and ERG channel blocker
GC31538 AT-1002
AT-1002是一种6聚体合成肽，是一种紧密连接的调节剂和吸收增强剂。
GC34477 AT-1002 TFA AT-1002TFA是一种6聚体合成肽，是一种紧密连接(junction)的调节剂和吸收增强剂。
GC42865 AT-121 A dual μ-opioid and nociceptin receptor partial agonist
GC39554 AT2 receptor agonist C21

AT2 receptor agonist C21
An AT₂ receptor agonist
GC18133 ATB-346

ATB-346
An H₂S-releasing NSAID
GC65596 Atogepant

MK-8031; AGN-241689
Atogepant (MK-8031) 是一种口服有效且具有选择性的降钙素基因相关肽受体 (CGRP) 拮抗剂。Atogepant 可用于研究偏头痛。
GC46891 ATPA (hydrate) An agonist of GluR5
GC15667 Atracurium Besylate

苯磺酸阿曲库铵,BW-33A
A neuromuscular blocking drug
GC16526 Atropine

阿托品; Tropine tropate; DL-Hyoscyamine
A non-selective muscarinic acetylcholine receptor antagonist
GC35427 Atropine methyl bromide

甲溴阿托品; Methylatropine bromide
A muscarinic acetylcholine receptor antagonist
GC35428 Atropine sulfate

硫酸阿托品; 硫酸阿妥品; 硫酸阿托平; 硫酸阿脱品; Tropine tropate sulfate; DL-Hyoscyamine sulfate; Sulfatropinol
A non-selective muscarinic acetylcholine receptor antagonist
GC63827 Atropine sulfate monohydrate

硫酸阿托品; Tropine tropate sulfate monohydrate; DL-Hyoscyamine sulfate monohydrate
A non-selective muscarinic acetylcholine receptor antagonist
GC46894 Atropine-d5

Tropine tropate-d5; DL-Hyoscyamine-d5
A neuropeptide with diverse biological activities
GC46895 Aurintricarboxylic Acid (ammonium salt)

铝试剂
A protein synthesis inhibitor with diverse biological activities
GC49646 Aurothioglucose (hydrate)

Gold Thioglucose
A TrxR inhibitor
GC46897 AUTEN-99

Autophagy enhancer-99 hydrobromide
An inhibitor of MRMR14/Jumpy
GC33683 Autocamtide 2 (Autocamtide II)

Autocamtide II
Autocamtide 2 (Autocamtide II) 是钙/钙调蛋白依赖性蛋白激酶 II (CaMKII) 的高选择性肽底物。
GC34390 Autocamtide 2, amide Autocamtide2,amide是钙调蛋白激酶(CaMK)家族实验的底物(100μMfinalconcentration)。
GC35432 Autocamtide-2-related inhibitory peptide (TFA) A CaMKII inhibitor
GC91849 Autocamtide-2-related Inhibitory Peptide (trifluoroacetate salt) Autocamtide-2-related inhibitory peptide is a calmodulin-dependent protein kinase II (CaMKII) inhibitor (IC50 = 40 nM) that was designed based on the sequence around the autophosphorylation site (Thr286/Thr287) in the autoinhibitory domain of the protein kinase.
GC50305 Autocamtide-2-related inhibitory peptide, myristoylated Autocamtide-2 相关抑制肽，肉豆蔻酰化是肉豆蔻酰化 Autocamtide-2 相关抑制肽。
GC72206 Autocamtide-3 acetate Autocamtide-3 acetate含有Thr287的13个氨基酸的肽是选择性CaMKII（Ca2+/钙调素依赖性激酶II）（CaMK）底物。
GC42877 AUY954 A selective S1P₁ receptor agonist
GC42881 Avermectin B1a aglycone An aglycone form of avermectin B_1a
GC30907 AVN-492 A 5-HT₆ receptor antagonist
GC10974 AWD 131-138

伊匹妥英,AWD 131-138
A partial agonist of the GABA_A receptor
GC42885 AX 048 A cPLA₂ inhibitor
GC49321 AZ-GHS-22 An inverse agonist of GHS-R1a
GC16229 Azaperone

阿扎哌隆,R-1929
An Analytical Reference Standard
GC35443 Azaphen

阿扎吩,Azafen; Pipofezin hydrochloride; Pipofezine hydrochloride
Pipofezine(Azafen,Azaphen)是5-羟色胺重吸收抑制剂。
GC35444 Azaphen dihydrochloride monohydrate

5-甲基-3-(4-甲基-1-哌嗪基)-5H-哒嗪并[3,4-B][1,4]苯并恶嗪二盐酸盐一水合物,Azafen dihydrochloride monohydrate; Pipofezin dihydrochloride monohydrate; Pipofezine dihydrochloride monohydrate; Azaphenonxazine dihydrochloride monohydrate
Pipofezine(Azafen，Azaphen)是5-羟色胺重吸收抑制剂。
GC15687 Azasetron HCl

盐酸阿扎司琼; Y-25130 hydrochloride
A 5-HT₃ receptor antagonist
GC14070 Azatadine

阿扎他定
An antihistamine with anticholinergic and antiserotonergic activities
GC15776 Azatadine dimaleate

马来酸阿扎他定; Azatadine maleate
An antihistamine with anticholinergic and antiserotonergic activities
GC31010 AZD-6280 AZD-6280 is a selective GABAA (α2/3) receptor modulator, used for treatment of generalized anxiety disorder.
GC31643 AZD1979 AZD1979是一个Melanin-concentratinghormonereceptor1(MCHr1)拮抗剂,其IC50值约为12nM。
GC14130 AZD3839 An inhibitor of BACE1