Descarbonyl-lacosamide is a potential impurity found in commercial preparations of lacosamide .1 It is a degradation product formed under acidic conditions.2
1.Molleti, S., Rao, V., and Jayaveera, K.N.Stability indicating RP-UPLC method for the determination of lacosamide and its impurities in bulk drugs and its pharmaceutical dosage formsDer Pharma Chemica5(1)81-89(2013) 2.Tiwari, R.N., and Bonde, C.G.Identification and characterization of degradation products of lacosamide by liquid-chromatography/time-of-flight mass spectrometric and multi-stage mass spectrometric analysisJ. Liq. Chromatogr.37(14)2046-2061(2014)
















