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Home >> Signaling Pathways >> Neuroscience

Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for  Neuroscience

  1. Cat.No. 产品名称 Information
  2. GP10046 Amyloid Precursor C-Terminal Peptide

    H2N-Gly-Tyr-Glu-Asn-Pro-Thr-Tyr-Lys-Phe-Phe-Glu-Gln-Met-Gln-Asn-OH

    For beta amyloid generation
  3. GP10057 Amyloid β-Peptide (10-20) (human)

    Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe

    Amyloid β-Peptide (10-20) (human) 是 Amyloid-&#946 的片段；肽，可用于神经系统疾病的研究。
  4. GP10094 Amyloid β-peptide (10-35), amide

    H2N-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-NH2

    Truncated peptide model
  5. GP10097 Amyloid β-Protein (1-15)

    H2N-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-OH

    淀粉样蛋白 β-蛋白 (1-15) 是 β-淀粉样蛋白肽的片段。
  6. GC46851 Amyloid-β (1-42) Peptide (trifluoroacetate salt)

    Aβ (1-42), Aβ42

     A 42-amino acid protein fragment of amyloid-β
  7. GC42801 Amyloid-β (1-8) Peptide

    Aβ (1-8)

     A wild-type control for amyloid-β (1-8, A2V) peptide
  8. GC42802 Amyloid-β (1-8, A2V) Peptide

    Aβ (1-8, A2V), Aβ (1-8) mutant, Amyloid-β (1-8) dominant negative

     A truncated form of Aβ containing the A2V mutation
  9. GC42803 Amyloid-β (25-35) Peptide (human) (trifluoroacetate salt)

    Aβ (25-35)

     An 11-residue amyloid-β protein fragment
  10. GC30866 Anabasine ((S)-Anabasine)

    (+)-假木贼碱; (S)-Anabasine; (+)-Anabasine

     Anabasine ((S)-Anabasine) ((S)-Anabasine ((S)-Anabasine)) 是一种生物碱，在烟草 (Nicotiana) 中是一种微量成分。
  11. GC39254 Anatabine dicitrate

    柠檬酸新烟草碱

     Anatabine dicitrate 是一种烟草生物碱，可以穿过血脑屏障。Anatabine dicitrate 是一种有效的 α4β2 nAChR 激动剂。Anatabine dicitrate 通过阻止淀粉样蛋白前体蛋白的 β 裂解，抑制 NF-κB 激活，并降低淀粉样 β (Aβ) 的产生。Anatabine dicitrate 具有抗炎作用，可用于神经退行性疾病的研究。
  12. GN10685 Anemarsaponin B

    知母皂苷 B

     Anemarsaponin B 是一种甾体皂苷。
  13. GC42809 Angiotensin II (3-8) (human, rat, mouse) (trifluoroacetate salt)

    Angiotensin IV (human, rat, mouse)

     A peptide vasoconstrictor
  14. GC46856 Angiotensin II (5-8) (human, rat, mouse) (trifluoroacetate salt)

    Angiotensin (5-8)

     An endogenous angiotensin II fragment
  15. GC49419 Aniline-d5

    苯胺-2,3,4,5,6-d5

     An internal standard for the quantification of aniline
  16. GC17695 Aniracetam

    茴拉西坦; Ro 13-5057

     An Analytical Reference Standard
  17. GC68659 Anisatin

    莽草毒素

     Anisatin 从一种日本植物 Illicium anisatum) 种子中分离出来的一种有毒物质，是一种类苦毒素的非竞争性 b>GABA 抗剂。Anisatin 以浓度依赖性方式抑制 GABA 诱导的电流，EC50 约为 1.10 μM。
  18. GC60049 Anisodamine hydrobromide

    氢溴酸山莨菪碱,6-Hydroxyhyoscyamine hydrobromide

     Anisodamine (6-Hydroxyhyoscyamine) is a naturally occurring atropine derivative and exhibits anti-inflammatory activity. It also inhibits α1-adrenergic receptors and muscarinic acetylcholine receptors (mAChRs).
  19. GC14008 Anpirtoline hydrochloride 5-HT1B receptor agonist
  20. GC31207 Ansofaxine hydrochloride (LY03005)

    5-氨基-1,3-二苯基吡唑,LY03005; LPM570065

     Ansofaxine hydrochloride (LY03005, LPM570065), a triple reuptake inhibitor, inhibits serotonin, dopamine and norepinephrine reuptake with IC50 values of 723, 491 and 763 nM, respectively.
  21. GC13899 Antazoline HCl

    盐酸安他唑啉,Phenazoline hydrochloride

     A histamine H1 receptor antagonist
  22. GC46858 Anthirine

    Antirhine

     An alkaloid with analgesic activity
  23. GC46859 Antide (acetate)

    N-((4R,7R,10R,13S,16S,19R)-19-(((S)-1-(((S)-1-((S)-2-((R)-1-氨基-1-氧代丙烷-2-基)氨基甲酰基)吡咯烷-1-基)-6-(异丙基氨基)-1-氧代己基-2-基)氨基)-4-甲基-1-氧代戊烷-2-基)氨基甲酰基)-7-(4-氯苄基)-13-(羟甲基)-4-(萘-2-基甲基)-16-(4-(烟酰胺基)丁基)-2,5,8,11,14,17-六氧代-10-(吡啶-3-基甲基)-3,6,9,12,15,18-六氮杂二十三烷-23-基)烟酰胺乙酸盐

     A GnRHR antagonist
  24. GC31141 Antihistamine-1 Antihistamine-1是能够渗透血脑屏障的H1-抗组胺药(Ki=6.9nM),它也是CYP2D6和hERG通道的抑制剂，其IC50值分别为5.4和0.8μM。
  25. GC49209 Antisauvagine-30 (trifluoroacetate salt)

    AS30, D-FHLLRKMIEIEKNEKEKNNAANNRLLLDTI-NH2, D-Phe11,His12Svg11-40, aSVG, aSvg-30

     A peptide CRF2 antagonist
  26. GC31134 AP521 AP521是一个人5-HT1A受体激动剂，其IC50值为94nM.
  27. GC48858 APHS A COX inhibitor
  28. GC30911 Apimostinel (NRX-1074)

    NRX-1074; AGN-241660

    Apimostinel (NRX-1074) (NRX-1074; AGN-241660) 是一种具有口服活性的 NMDA 受体部分激动剂。
  29. GC15200 Aprepitant

    阿瑞匹坦; MK-0869; MK-869; L-754030

     An antiemetic and NK1 antagonist
  30. GC46868 Aprepitant-d4

    阿瑞匹坦-d4

     An internal standard for the quantification of aprepitant
  31. GC60592 APS6-45 APS6-45(Compound 10) is an orally active tumor-calibrated inhibitor (TCI) that inhibits RAS/MAPK signaling and exhibits antitumor activity.
  32. GC13340 AQ-RA 741 M2 antagonist,selective and high affinity
  33. GC31291 AR-A 2 (AR-A 000002)

    AR-A 000002

     AR-A 2 (AR-A 000002) 是一种选择性 5-HT1B 受体拮抗剂，对豚鼠皮层 5HT1B/1D 和重组豚鼠 5-HT1B 受体具有高亲和力（Ki=0.24 和 0.47 nM），具有 10 倍的亲和力。对豚鼠 5-HT1D 受体的亲和力较低 (Ki, 5 nM)，对豚鼠 5-HT1B 受体的 EC50 为 4.5 nM； AR-A 2 (AR-A 000002) 可用于抑郁和焦虑的研究。
  34. GC11060 AR-R 17779 hydrochloride AR-R 17779 hydrochloride 是一种有效的、选择性的 nAChR 完全激动剂，对 α7 和 α4β2 亚型的 Kis 分别为 92 和 16000 nM。
  35. GC49473 ARA 290 (acetate)

    Cibinetide, PHBSP, Pyroglutamate HBSP, Pyroglutamate Helix B Surface Peptide

     A derivative of EPO
  36. GC52514 Arachidonic Acid-d11 ethyl ester

    C20:4 (cis-5,8,11,14)-d11 ethyl ester, Ethyl Arachidonate-d11, Ethyl (cis-5,8,11,14)-eicosatetraenoate-d11

     An internal standard for the quantification of arachidonic acid ethyl ester
  37. GC46877 Arachidonoyl Glycine-d8

    NAGlyd8, NArachidonyl Glycined8

     An internal standard for the quantification of arachidonoyl glycine
  38. GC63654 Aramisulpride

    R-(+)-Amisulpride

     Aramisulpride是一种多巴胺D2受体和血清素受体拮抗剂，用于研究代谢紊乱。
  39. GC35381 Arborine

    山柑子碱

     Arborine 可从 Glycosmis arborea 中分离。Arborine 抑制乙酰胆碱的外周作用并诱导血压下降。
  40. GC60596 Arecaidine

    槟榔次碱

     Arecaidine，一种吡啶生物碱，是一种有效的GABA吸收抑制剂。Arecaidine是H+偶联的氨基酸转运蛋白1(PAT1，SLC36A1)的底物，竞争性抑制L-脯氨酸的摄取。
  41. GC11415 Arecaidine but-2-ynyl ester tosylate mAChR M2 激动剂
  42. GC63879 Arecaidine hydrochloride

    盐酸槟榔次碱

     Arecaidine hydrochloride, a constituent of the nut of Areca catechu, inhibits the uptake of GABA and beta-alanine, but not that of glycine.
  43. GC16504 Arecaidine propargyl ester tosylate muscarinic receptor agonist
  44. GC10264 Arecoline hydrobromide

    氢溴酸槟榔碱

     Muscarinic acetylcholine receptor agonist
  45. GC42852 Arginine Vasotocin (trifluoroacetate salt)

    Arg8-Vasotocin, AVT

     A nonapeptide agonist of the AVT receptor
  46. GC52332 Arimoclomol

    BRX-220

     A co-inducer of heat shock proteins
  47. GC10117 Aripiprazole

    阿立哌唑; OPC-14597

     An atypical antipsychotic
  48. GC35386 Aripiprazole D8

    OPC-14597 D8

     An internal standard for the quantification of aripiprazole
  49. GC52168 Aripiprazole N,N-dioxide

    阿立哌唑,1,4-二氮氧化物

     A metabolite of aripiprazole
  50. GC52024 Aripiprazole N-oxide

    阿立哌唑-N1-氧化物

     A metabolite of aripiprazole
  51. GC68687 Aripiprazole-d8

    阿立哌唑-D8; OPC-14597-d8

     Aripiprazole-d8 是 Aripiprazole 的氘代物。

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