GlpBio

[D-Lys3]-GHRP-6 (trifluoroacetate salt)

目录号: GC52388纯度: >95.00%同义词: D-Lys3-Growth Hormone Releasing Peptide 6, His-D-Trp-D-Lys-Trp-D-Phe-Lys-NH2
An antagonist of GHS-R1a
[D-Lys3]-GHRP-6 (trifluoroacetate salt)
规格价格库存数量操作
5 mg¥1,162.00现货
1
10 mg¥2,086.00现货
1
25 mg¥3,766.00现货
1
50 mg¥6,370.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

[D-Lys3]-GHRP-6 is an antagonist of the growth hormone secretagogue receptor 1a (GHS-R1a; Ki = 4.25 nM).1 It inhibits ghrelin-induced cAMP accumulation in human aortic smooth muscle cells when used at a concentration of 20 nM. [D-Lys3]-GHRP-6 (12 mg/kg) decreases food intake in Zucker FA/FA lean and fa/fa obese rats.2

1.Rossi, F., Castelli, A., Bianco, M.J., et al.Ghrelin inhibits contraction and proliferation of human aortic smooth muscle cells by cAMP/PKA pathway activationAtherosclerosis203(1)97-104(2008) 2.Beck, B., Richy, S., and Sticker-Krongrad, A.Feeding response to ghrelin agonist and antagonist in lean and obese Zucker ratsLife Sci.76(4)473-478(2004)

产品文档 Product Documents

Purity:>95.00%Appearance:A solid

化学性质Chemical Properties

同义词
D-Lys3-Growth Hormone Releasing Peptide 6, His-D-Trp-D-Lys-Trp-D-Phe-Lys-NH2
SMILES
OC(C(F)(F)F)=O.NCCCC[C@@H](C(N)=O)NC([C@@H](CC1=CC=CC=C1)NC([C@@H](NC([C@@H](CCCCN)NC([C@H](NC([C@@H](N)CC2=CN=CN2)=O)CC3=CNC4=CC=CC=C34)=O)=O)CC5=CNC6=CC=CC=C56)=O)=O
分子式
C49H63N13O6 ? XCF3COOH
分子量
930.1 g/mol
溶解性
DMF: 2 mg/ml,DMSO: 2 mg/ml,Ethanol: 1 mg/ml,PBS (pH 7.2): 5 mg/ml
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol