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Home >> Signaling Pathways >> Neuroscience

Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for  Neuroscience

  1. Cat.No. 产品名称 Information
  2. GC60740 Dapoxetine-D7 hydrochloride

    LY-210448-d7 hydrochloride

     Dapoxetine-D7(LY-210448-D7)hydrochloride是Dapoxetinehydrochloride的氘代物。Dapoxetinehydrochloride是一种短效的选择性5-羟色胺再摄取抑制剂(SSRI)。
  3. GC12942 DAPT (GSI-IX)

    gamma-Secretase Inhibitor IX, DAPT, GSI-IX

     DAPT (GSI-IX) 是一种具有口服活性的 γ-分泌酶抑制剂，对人原代神经元培养物中产生的总淀粉样蛋白-β (Aβ) 和 Aβ42 的 IC50 分别为 115 nM 和 200 nM。
  4. GC48359 DAPTA (acetate)

    D-Ala-peptide T-amide

     A CCR5 receptor antagonist
  5. GC31136 Darenzepine

    达仑西平

     Darenzepine是一种毒蕈碱受体抑制剂，来自专利US20170095465A1。
  6. GC35810 Darifenacin

    达非那新,(±)-UK-88525

     Darifenacin HBr (UK-88525) is a selective M3 muscarinic receptor antagonist with pKi of 8.9.
  7. GC15772 Darifenacin HBr

    氢溴酸达非那新; UK-88525 hydrobromide

     A muscarinic M3 receptor antagonist
  8. GC49797 Darifenacin N-oxide A potential impurity found in commercial preparations of darifenacin
  9. GC48527 Darifenacin-d4

    (±)-UK-88525-d4

     An internal standard for the quantification of darifenacin
  10. GC19117 Dasotraline

    SEP 225289

     Dasotraline 是一种三重再摄取抑制剂，可阻断多巴胺、去甲肾上腺素和血清素转运蛋白，IC50 值分别为 4、6 和 11 nM。
  11. GC19118 Dasotraline hydrochloride

    达索曲林盐酸盐,SEP-225289 hydrochloride

     Dasotraline hydrochloride (SEP-225289 hydrochloride) 是一种三重再摄取抑制剂，可阻断多巴胺、去甲肾上腺素和血清素转运蛋白，IC50 值分别为 4、6 和 11 nM。
  12. GC10633 DAU 5884 hydrochloride muscarinic M3 receptor antagonist
  13. GC50733 Davunetide A neuroprotective ADNP-derived peptide
  14. GC49913 Davunetide (acetate)

    AL-108, NAP, NAPVSIPQ

     A neuroprotective ADNP-derived peptide
  15. GC43383 DBO-83 An agonist of nAChRs
  16. GC15385 DCB DCB (3,3'-dichlorobenzaldazine) 是代谢型谷氨酸受体代谢型谷氨酸受体亚型 5 (mGluR5) 的中性变构调节剂。
  17. GC16247 DCG IV DCG IV 是 II 组 mGluRs 的有效激动剂，对 mGlu2R 和 mGlu3R 的 EC50 分别为 0.35 和 0.09 μM。
  18. GC35820 DDD107498 succinate

    DDD107498 succinate; DDD-498 succinate; M5717 succinate

     DDD107498 (M-5717, DDD-498) is a P. falciparum translation elongation factor 2 inhibitor. DDD107498 exhibits a potent and novel spectrum of antimalarial activity against multiple life-cycle stages of the Plasmodium parasite.
  19. GC47175 Deacetylforskolin

    脱乙酰毛喉素来源于毛喉鞘蕊花

     A diterpene with diverse biological activities
  20. GC16255 Decamethonium Bromide

    十烃溴铵

     A depolarizing neuromuscular blocking agent
  21. GC43391 Decanoic Acid (sodium salt)

    癸酸钠

     A medium-chain saturated fatty acid
  22. GC45815 Decanoic Acid-d19

    癸酸 d19

     An internal standard for the quantification of decanoic acid
  23. GC46127 Decanoic Acid-d2

    癸酸 d2

     An internal standard for the quantification of decanoic acid
  24. GC45722 Decanoic Acid-d3

    癸酸 d3

     An internal standard for the quantification of decanoic acid
  25. GC68954 Decanoic acid-d5 Decanoic acid-d5 是 Decanoic acid 氘代物。Decanoic acid 是中链甘油三酯中的一种成分，是一种可透过血脑屏障的 AMPA 受体的非竞争性抑制剂。Decanoic acid 具有抗癫痫作用。
  26. GC10321 Decloxizine

    去氯羟嗪; UCB-1402; NSC289116

     Decloxizine(UCB-1402; NSC289116) 是一种组胺 1 受体拮抗剂。
  27. GC35826 Decloxizine dihydrochloride

    盐酸去氯羟嗪; UCB 1402 dihydrochloride

     Decloxizine（UCB-1402; NSC289116）二盐酸盐1型组胺受体H1拮抗剂。
  28. GC41151 Decursinol angelate Decursinol angelate is a pyranocoumarin that has been found in the Korean medicinal herb A.
  29. GC45765 Deferiprone-d3

    去铁酮 d3

     An internal standard for the quantification of deferiprone
  30. GC13554 Deferoxamine mesylate

    甲磺酸去铁胺; Desferrioxamine B mesylate; DFOM

     Deferoxamine mesylate 是一种通过形成稳定的复合物来螯合铁的药物，该复合物可防止铁进入进一步的化学反应，并用于治疗输血依赖性贫血患者的慢性铁过载。
  31. GC43400 Dehydro Aripiprazole (hydrochloride)

    脱氢阿立哌唑盐酸盐

     The primary, active metabolite of aripiprazole
  32. GC39705 Dehydroaripiprazole

    7-[4-[4-(2,3-二氯苯基)-1-哌嗪基]丁氧基]-2(1H)-喹啉酮,OPC-14857; DM-14857

     Dehydroaripiprazole (OPC-14857) 是 Aripiprazole 的活性代谢产物。Aripiprazole 是一种抗精神病药，被 CYP3A4 和 CYP2D6 代谢，主要形成 Dehydroaripiprazole。Dehydroaripiprazole 具有与 Aripiprazole 同等的抗精神病活性。
  33. GC38184 Dehydrodiisoeugenol

    脱氢二异丁香酚

     Dehydrodiisoeugenol, a naturally occurring lignan from Aristolochia taliscana (Aristolochiaceae), acts as a potent anti-inflammatory agent and shows various pharmacological activities, including anti-lipid peroxidation, anti-bacteial function, and hepatic drug metabolism enzyme inhibition.
  34. GC38431 Dehydroevodiamine

    脱氢吴茱萸碱

     An alkaloid with diverse biological activities
  35. GC38625 Dehydronuciferine

    去氢荷叶碱

     Dehydronuciferine 从 Nelumbo nucifera Gaertn 的叶子中分离，是一种乙酰胆碱酯酶 (AChE) 抑制剂，其 IC50 为 25 μg/mL。
  36. GC47184 Deltorphin C (trifluoroacetate salt)

    Deltorphin I, D-Ala2Deltorphin

     A neuropeptide with diverse biological activities
  37. GC49338 Deltorphin II (trifluoroacetate salt)

    DADELT II, D-Ala2Deltorphin II, D-Ala2, Glu4Deltorphin II, Tyr-D-Ala-Phe-Glu-Val-Val-Gly-NH2

     A peptide agonist of δ2-opioid receptors
  38. GC31190 Demecarium Bromide (BC-48)

    地美溴铵; BC-48

     Demecarium Bromide (BC-48) (BC-48) 是一种有效的胆碱酯酶抑制剂，表观亲和力 (Kiapp) 为 0.15 μM.
  39. GC47186 Deoxy Donepezil (hydrochloride)

    1-苄基-4-((5,6-二甲氧基-2,3-二氢-1H-茚-2-基)甲基)哌啶盐酸盐

     A potential impurity found in bulk preparations of donepezil
  40. GC18869 Deoxyenterocin

    5-Deoxyenterocin

     A bacterial metabolite with diverse biological activities
  41. GC16077 Deracoxib

    地拉考昔; SC 046; SC 46; SC 59046

     An NSAID and selective COX-2 inhibitor
  42. GC33722 Deramciclane (EGIS-3886)

    德伦环烷,EGIS-3886

     Deramciclane (EGIS-3886) 对 5-HT2A 和 5-HT2C 受体具有高亲和力；它作为两种受体亚型的拮抗剂，在没有直接刺激激动剂的情况下对 5-HT2C 受体具有反向激动剂特性。
  43. GC47188 Dermorphin (acetate) An opioid peptide
  44. GC18135 Derquantel

    得曲恩特,PF-00520904,PNU 141962,2-deoxy-Paraherquamide

     An anthelmintic spiroindole
  45. GC40616 Des-4-fluorobenzyl Mosapride

    莫沙必利脱氟苄基杂质

     A metabolite of mosapride
  46. GC49242 Descarbonyl Lacosamide

    (2R)-2-氨基-3-甲氧基-N-(苯基甲基)丙酰胺

     A potential impurity found in commercial preparations of lacosamide
  47. GC60758 Deschloroclozapine

    氯氮平杂质

     Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs (muscarinic Designer Receptors Exclusively Activated by Designer Drugs) agonist, and binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively.
  48. GC74124 Deschloroclozapine dihydrochloride Deschloroclozapine dihydrochloride氯氮平的代谢产物，是一种强效毒蕈碱类DREADDs激动剂。
  49. GC49817 Desethoxy Quetiapine (hydrochloride)

    喹硫平羟基杂质二盐酸盐

     An active metabolite of quetiapine
  50. GC35842 Desfesoterodine

    (R)-5-羟甲基托特罗定; PNU-200577; 5-Hydroxymethyl Tolterodine

     5-hydroxymethyl Tolterodine (PNU 200577, 5-HMT, 5-HM,Desfesoterodine) is a new muscarinic receptor antagonist with Kb of 0.84 nM.
  51. GC12593 Desformylflustrabromine hydrochloride

    Deformylflustrabromine hydrochloride; dFBr hydrochloride

     Desformylflustrabromine hydrochloride 是 α4β2 神经元烟碱乙酰胆碱受体 (nAChR) 的选择性激动剂，pEC50 为 6.48。

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