Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for Neuroscience

Cat.No. 产品名称 Information
GC11883 Dimaprit dihydrochloride

S-(3-二甲氨基丙基)异硫脲二盐酸盐
A histamine H₂ receptor agonist
GC15723 Dimebolin

2,3,4,5-四氢-2,8-二甲基-5-[2-(6-甲基吡啶-3-基)乙基]-1H-吡啶并[4,3-B]吲哚,Dimebon?
A neuroprotective agent
GC30902 Dimenhydrinate

乘晕宁
Dimenhydrinate is an over-the-counter drug used to prevent nausea, vomiting, and dizziness caused by motion sickness.
GC66445 Dimethindene maleate Dimethindene maleate 是一种选择性的 histamine H1 拮抗剂，具有抗组胺效应。Dimethindene maleate 可用于过敏性反应的研究。
GC43468 Dimethyl-W84 (dibromide) A selective M₂ receptor allosteric modulator
GC32185 Dinotefuran (MTI-446)

呋虫胺; MTI-446
A neonicotinoid insecticide
GC45434 Dipeptide diaminobutyroyl benzylamide (acetate)

类蛇毒三肽
A biomimetic peptide and muscarinic acetylcholine receptor antagonist
GC16635 Diphemanil Methylsulfate

甲硫二苯马尼,Diphemanil mesylate
An anticholinergic agent
GC10445 Diphenhydramine HCl

盐酸苯海拉明
An antagonist of histamine and muscarinic receptors
GC68984 Diphenhydramine-d5 hydrochloride

盐酸苯海拉明 d₅ (盐酸盐)
Diphenhydramine-d5 (hydrochloride) 是 Diphenhydramine hydrochloride 的氘代物。Diphenhydramine hydrochloride 是第一代具有抗胆碱能作用的组胺 H1 受体 (histamine H1-receptor) 拮抗剂。Diphenhydramine hydrochloride 能透过血脑屏障。
GC68985 Diphenhydramine-d6 hydrochloride

盐酸苯海拉明 d₆ (盐酸盐)
Diphenhydramine-d6 (hydrochloride) 是 Diphenhydramine hydrochloride 的氘代物。Diphenhydramine hydrochloride 是第一代具有抗胆碱能作用的组胺 H1 受体 (histamine H1-receptor) 拮抗剂。Diphenhydramine hydrochloride 能透过血脑屏障。
GC10300 Diphenidol HCl

盐酸地芬尼多; Difenidol hydrochloride
A muscarinic acetylcholine receptor antagonist
GC49129 Diphenidol-d10 An internal standard for the quantification of diphenidol
GC48835 Diphenylpyraline

二苯拉林；双苯拉林
A histamine H₁ receptor antagonist
GC14984 Diphenylpyraline HCl

盐酸双苯比拉林,4-Diphenylmethoxy-1-methylpiperidine hydrochloride
A histamine H₁ receptor antagonist
GC46134 Dityrosine (hydrochloride)

Bityrosine, o,o-Ditryosine
A neuropeptide with diverse biological activities
GC14687 DL-AP4

DL-2-氨基-4-磷丁酸,NSC 30079;NSC 354086
A broad-spectrum glutamatergic antagonist
GC12960 DL-AP4 Sodium salt A broad-spectrum glutamatergic antagonist
GC90686 DL-Dapoxetine (hydrochloride)

(±)-Dapoxetine

一种(R)-达泊西汀和(S)-达泊西汀的外消旋混合物。
GC49672 DL-erythro-PDMP (hydrochloride) A mixture of PDMP isomers
GC19941 DL-Leucic Acid
GC63881 DL-Phenylalanine-d5 hydrochloride

2-Amino-3-phenylpropionic acid-d5 hydrochloride
DL-Phenylalanine-d5 (2-Amino-3-phenylpropionic acid-d5) hydrochloride 是 DL-Phenylalanine 的氘代物。L-Phenylalanine hydrochloride 是分离自大肠杆菌的必需氨基酸。L-Phenylalanine hydrochloride 是一种电压依赖性 α2δ 亚基 Ca2+ 通道拮抗剂，Ki 为 980 nM。L-Phenylala
GC19686 DL-Pyroglutamic acid

DL-焦谷氨酸
GC49829 DL-threo-β-Hydroxyaspartic Acid

D,L-苏-Β-羟基天门冬氨酸
An EAAT inhibitor
GC43494 DL-threo-PDMP (hydrochloride) An inhibitor of sphingolipid biosynthesis
GC43495 DL-Tryptophan octyl ester (hydrochloride)

D,L-色氨酸正辛酯盐酸盐
A tryptophan derivative
GC13405 DMCM hydrochloride DMCM hydrochloride 是苯二氮卓类的非选择性全反向激动剂。
GC13126 DMeOB Negative allosteric modulator of mGlu5
GC52120 DMPE-MPEG(2000)

1,2-Dimyristoyl-rac-glycero-3-PE-methoxy-Polyethyleneglycol-2000, 1,2-DMPE-MPEG(2000)
A PEGylated form of DMPE
GC73830 DN5355 DN5355是一种小分子化合物，靶向淀粉样β蛋白（aβ）和过磷酸化tau蛋白。
GC32755 DNQX (FG 9041)

二硝基喹酮; FG 9041
A non-NMDA glutamate receptor antagonist
GC45995 DO264 An ABHD12 inhibitor
GC49590 Docosahexaenoic Acid 1,2,3,4-13C

C22:6 n-3 1,2,3,4-13C, C22:6(4Z,7Z,10Z,13Z,16Z,19Z) 1,2,3,4-13C, Cervonic Acid 1,2,3,4-13C, DHA 1,2,3,4-13C
An internal standard for the quantification of DHA
GC45438 Docosahexaenoic Acid ethyl ester

(4Z,7Z,10Z,13Z,16Z,19Z)-4,7,10,13,16,19-二十二碳六烯酸乙酯,Ethyl docosahexaenoate
An ω-3 fatty acid ethyl ester
GC26233 Docosahexaenoic Acid-d5

C22:6 n-3-d5 C22:6(4Z,7Z,10Z,13Z,16Z,19Z)-d5 Cervonic Acid-d5 DHA-d5 4,7,10,13,16,19-Docosahexaenoic Acid-d5

Docosahexaenoic acid-d5 (DHA-d5) is intended for use as an internal standard for the quantification of DHA (Item No. 90310) by GC- or LC-MS.
GC90697 Docosahexaenoic Acid-d5 ethyl ester

4,7,10,13,16,19-Docosahexaenoic Acid-d5 ethyl ester, C22:6(4Z,7Z,10Z,13Z,16Z,19Z)-d5 ethyl ester, C22:6 n-3-d5 ethyl ester, Cervonic Acid-d5 ethyl ester, DHA-d5 ethyl ester

无适用信息。
GC43556 Docosahexaenoyl Glycine Docosahexaenoyl glycine
GC30412 Dolasetron (MDL-73147)

多拉司琼,MDL-73147
A 5-HT₃ receptor antagonist
GC30413 Dolasetron Mesylate (MDL-73147EF)

甲磺酸多拉司琼,MDL-73147EF
A 5-HT₃ receptor antagonist
GC30198 Dolasetron Mesylate hydrate

甲磺酸多拉司琼,MDL-73147EF hydrate
A 5-HT₃ receptor antagonist
GC49056 Dolasetron-d4

MDL-73147-d4
An internal standard for the quantification of dolasetron
GC10144 Domperidone

多潘立酮; R33812
A dopamine D₂ receptor antagonist
GC71653 Domperidone monomaleate Domperidone monomaleate是一种口服活性和选择性多巴胺-2受体拮抗剂。
GC47262 Domperidone-d6

多潘立酮 d6
An internal standard for the quantification of domperidone
GC68996 Donanemab

LY3002813
Donanemab是一种人源化IgG1单克隆抗体。Donanemab靶向沉积的Aβ42，并通过小胶质细胞介导的吞噬作用清除脑内淀粉样斑块。Donanemab主要定位于血浆和细胞外空间，并可穿过血脑屏障进入脑部与Aβ沉积物结合。Donanemab是治疗阿尔茨海默病的有效药物。
GC47263 Donecopride (fumarate hydrate)

MR31147
A 5-HT₄ receptor partial agonist and AChE inhibitor
GC30810 Donepezil (E2020)

多奈哌齐; E2020 free base
Donepezil (E2020)是一种乙酰胆碱酯酶（AChE）抑制剂，IC50为6.7nM。
GC14490 Donepezil HCl

盐酸多奈哌齐; E2020

An AChE inhibitor
GC40018 Donepezil N-oxide

多奈哌齐N氧化物
An active metabolite of donepezil
GC47264 Donepezil-d4 (hydrochloride)

多奈哌齐-D4,E2020-d4
An internal standard for the quantification of donepezil