• 0
    My Cart

    Click Here to Find How Many Items You Have Added:)

qq在线咨询
Home >> Signaling Pathways >> Neuroscience

Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for  Neuroscience

  1. Cat.No. 产品名称 Information
  2. GC63334 Donepezil-d7 hydrochloride

    E2020-d7

     Donepezil-d7 (hydrochloride) (E2020-d7) 是 Donepezil 的氘代物。Donepezil (E2020 free base) 是 AChE 抑制剂，对牛 AChE 和人 AChE 的 IC50 分别为 8.12 nM 和 11.6 nM。
  3. GC35894 Donitriptan

    多尼普曲坦

     Donitriptan 是一种有效的高亲和力 5-HT1B/1D 受体激动剂，pKi 分别为 9.4 和 9.3。
  4. GC40945 DOPAL

    屈昔多巴杂质2

    A toxic dopamine metabolite
  5. GC62940 Dopamine

    2-(3,4-二羟基苯基)乙胺,ASL279 free base; 4-(2-Aminoethyl)benzene-1,2-diol

    An endogenous catecholamine
  6. GC49166 Dopamine 3-O-Sulfate

    DA-3S, Dopamine 3-Sulfate

     A metabolite of dopamine
  7. GC49516 Dopamine 4-O-Sulfate

    DA-4S, Dopamine 4-Sulfate

     An inactive metabolite of dopamine
  8. GC71157 Dopamine D2 receptor agonist-2 Dopamine D2 receptor agonist-2(化合物36)是一种有效的多巴胺D2受体偏向性激动配体，Ki值为11.2 nM。
  9. GC90810 Dopamine D3 Receptor Agonist 13a

    一种多巴胺D3受体激动剂
  10. GC11028 Dopamine HCl

    盐酸多巴胺,ASL279

     An endogenous catecholamine
  11. GC30772 Dopamine serotonin antagonist-1

    氯氮平杂质,Deschloroclozapine

     Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs (muscarinic Designer Receptors Exclusively Activated by Designer Drugs) agonist, and binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively.
  12. GC49497 Dopamine-d4 (hydrochloride)

    盐酸多巴胺D4,ASL279-d4

     An internal standard for the quantification of dopamine
  13. GC68997 Dopamine-d5 hydrochloride Dopamine-d5 (hydrochloride) 是一种氘代标记的 Dopamine (hydrochloride)。Dopamine hydrochloride (ASL279) 是在脑黑质，脑腹侧被盖区和下丘脑中产生的一种儿茶酚胺类神经递质，在大脑和身体中起着重要作用。Dopamine hydrochloride (ASL279) 通过 D2 多巴胺受体 (D2 dopamine receptor) 来诱导 VEGFR2 的内吞作用，这对于促进血管生成是至关重要的。
  14. GC47267 Dorzolamide-d5 (hydrochloride)

    L-671,152-d5, MK-507-d5

     A neuropeptide with diverse biological activities
  15. GC70555 Dothiepin Dothiepin（Dosulepin；Dothep）是一种具有镇静/抗焦虑活性的抗抑郁药物。
  16. GC34559 DOV-216,303 Free Base

    1-(3,4-二氯苯基)-3-氮杂双环[3.1.0]己烷

     DOV-216,303(FreeBase)是有效的5-羟色胺、去甲肾上腺素、多巴胺再摄取的三重抑制剂，其对hSERT、hNET和hDAT的IC50值分别为14nM，20nM和78nM。在嗅球切除大鼠模型中，可增加前额皮质中单胺的释放及具有抗抑郁的作用。
  17. GC63590 Doxefazepam

    度氟西泮,SAS-643

     Doxefazepam 是一种苯并二氮 (benzodiazepine) 衍生物。具有抗焦虑，抗惊厥作用。
  18. GC12892 Doxepin (hydrochloride)

    盐酸多塞平

     A tricyclic antidepressant
  19. GC60791 Doxepin D3 Hydrochloride

    盐酸多塞平 D3

     DoxepinD3Hydrochloride是DoxepinHydrochloride的氘代物。Doxepinhydrochloride是一种口服活性的三环抗抑郁药。Doxepinhydrochloride是一种有效的选择性组胺受体H1拮抗剂。Doxepinhydrochloride也是一种有效的CYP450抑制剂，并显着抑制CYP4502C19和CYP4501A2。
  20. GC91278 Doxepin N-oxide (hydrate)

    多西平的代谢产物。
  21. GC30496 Doxylamine D5 succinate

    琥珀酸多西拉敏 D5

     DoxylamineD5琥珀酸盐是Doxylamine氘代化合物标准品。
  22. GC14051 Doxylamine Succinate

    琥珀酸多西拉敏

     An Analytical Reference Standard
  23. GC43568 DPDPE (trifluoroacetate salt)

    D-Pen2,D-Pen5Enkephalin

     A synthetic pepetide δ-opioid receptor agonist
  24. GC14742 DPPE fumarate

    DPPE fumarate

     An AEBS ligand
  25. GC92004 DPTIP (hydrochloride) DPTIP (hydrochloride)是中性鞘磷脂酶2nMase2的抑制剂；IC50=30 nM。
  26. GC65140 DRAK2-IN-1 DRAK2-IN-1，化合物 16，是一种有效的选择性 ATP 竞争性的 DRAK2 抑制剂，IC50 和 Ki 值分别为 3 nM 和 0.26 nM。DRAK2-IN-1 对 DRAK1 具有抑制作用 (IC50=51 nM)。
  27. GC30849 DREADD agonist 21 A muscarinic hM3Dq DREADD agonist
  28. GC50446 DREADD agonist 21 dihydrochloride A muscarinic hM3Dq DREADD agonist
  29. GC30908 Drofenine hydrochloride (Hexahydroadiphenine hydrochloride)

    盐酸六氢芬宁,Hexahydroadiphenine hydrochloride

     Drofenine hydrochloride is a potent competitive inhibitor of BChE. It is an anticholinergic that acts both at the level of the nerves and the muscle fibers.
  30. GC16073 Dronedarone

    决奈达隆; SR 33589

     An antiarrhythmic agent
  31. GC10808 Droperidol

    氟哌啶; Dehydrobenzperidol

     A dopamine D2 and D4 receptor antagonist
  32. GC65014 DSP-1053 DSP-1053 是一种苄基哌啶衍生物，一种有效的血清素转运蛋白 (SERT) 抑制剂，Ki 值为 1.02 nM。DSP-1053 显示部分 5-HT1A 受体激动活性，Ki 值为 5.05 nM。DSP-1053 具有抗抑郁活性。
  33. GC49058 DTPA

    二乙烯三胺五醋酸,Diethylenetriaminepentaacetic acid; DTPA

     A cell-impermeable metal chelating agent
  34. GC31064 Duloxetine ((S)-Duloxetine)

    度洛西汀; (S)-Duloxetine; LY248686

     Duloxetine (LY-248686) is a potent inhibitor of serotonin (5-hydroxytryptamine, 5-HT) and noradrenaline (NE) uptake in vitro and in vivo and is 3- to 5-times more effective at inhibiting 5-HT uptake.
  35. GC13871 Duloxetine HCl

    盐酸度洛西汀; (S)-Duloxetine hydrochloride; LY-248686 hydrochloride

     A serotonin and norepinephrine reuptake inhibitor
  36. GC47277 Duloxetine-d3 (hydrochloride)

    (Rac)-Duloxetine-d3 hydrochloride

     An internal standard for the quantification of duloxetine
  37. GC12156 DuP 697

    5-溴-2-（4-氟苯基）-3-（4-甲基磺酰基苯基）噻吩

     A selective COX-2 inhibitor
  38. GC31083 DWK-1339 (MDR-1339)

    DWK-1339

     An inhibitor of amyloid-β aggregation
  39. GP10070 Dynorphin (2-17), amide, porcine

    H2N-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-amide

    A modulator of pain response
  40. GC35917 Dynorphin A (1-10) TFA Dynorphin A (1-10) (TFA) 是一种内源性的阿片样神经肽，与 κ 阿片受体 (κ-opioid receptor) 结合。Dynorphin A (1-10) (TFA) 也阻断 NMDA 激活的电流，IC50 为 42.0 μM。
  41. GC52500 Dynorphin A (trifluoroacetate salt)

    Dynorphin A (1-17)

     An endogenous opioid receptor agonist
  42. GC49507 Dynorphin A (trifluroacetate salt) An endogenous opioid receptor agonist
  43. GC35918 Dynorphin A 1-10 Dynorphin A (1-10) 是一种内源性的阿片样神经肽，与 κ 阿片受体 (κ-opioid receptor) 结合。Dynorphin A (1-10) 也阻断 NMDA 激活的电流，IC50 为 42.0 μM。
  44. GC43582 Dynorphin B (1-9) (trifluoroacetate salt) A neuropeptide
  45. GC69035 E-3620 E-3620 是一种有效的 5-HT3 受体拮抗剂。E-3620 可用于运动障碍和胃肠动力障碍研究。
  46. GC13192 E4CPG

    (RS)-ECPG

     An antagonist of mGluR1 and mGluR2
  47. GC91497 EB 47 (hydrochloride) EB 47 is an inhibitor of poly(ADP-ribose) polymerase 1 (PARP1; IC50 = 45 nM) and a dual site inhibitor of tankyrase 2 (TNKS2; IC50 = 45 nM).
  48. GC15713 Ebastine

    依巴斯汀; LAS-W 090; RP64305

     A histamine H1 receptor antagonist and prodrug form of carebastine
  49. GC16089 Ebrotidine

    乙溴替丁,FI 3542;Ulsanic;FI-3542;FI3542

     Ebrotidine(FI 3542) 是一种竞争性 H2 受体拮抗剂 (Ki= 127.5 nM)，具有有效的抗分泌活性和明显的胃保护作用。
  50. GC18648 Echothiophate (iodide)

    碘依可酯,Echothiophate iodide

     An AChE inhibitor
  51. GC30823 Edonerpic maleate (T-817 maleate)

    1-(3-(2-(苯并[B]噻吩-5-基)乙氧基)丙基)氮杂环丁烷-3-醇马来酸,T-817 maleate; T-817MA

     T-817MA propyl}-3-azetidinol maleate] 是一种新合成的阿尔茨海默病 (AD) 治疗剂，具有神经保护作用β-淀粉样肽 (Aβ) 的毒性和促进神经突生长的作用.T-817MA 预处理 24 小时后，T-817MA 在 0.1 和 1 uM 时显着防止 H2O2 处理引起的神经元损伤。

Items 1501 to 1550 of 3961 total

per page
  2. 29
  3. 30
  4. 31
  5. 32
  6. 33

Set Descending Direction