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Home >> Signaling Pathways >> Neuroscience

Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for  Neuroscience

  1. Cat.No. 产品名称 Information
  2. GC69077 Eptinezumab Eptinezumab 是一种人单克隆抗体。Eptinezumab 结合降钙素基因相关肽 (CGRP) 并阻断其与受体的结合。Eptinezumab 可用于预防成人偏头痛。
  3. GC69081 Erenumab Erenumab 是一种全人单克隆抗体。Erenumab 抑制降钙素基因相关肽 (CGRP) 受体。Erenumab 可用于预防发作性偏头痛。
  4. GC13161 Escitalopram

    艾司西酞普兰; (S)-Citalopram; (S)-(+)-Citalopram

     A selective serotonin reuptake inhibitor
  5. GC16797 Escitalopram Oxalate

    依他普仑草酸盐; (S)-Citalopram oxalate; (S)-(+)-Citalopram oxalate

     A selective serotonin reuptake inhibitor
  6. GN10004 EsculentosideA

    商陆皂苷甲

     EsculentosideA (EsA)，一种从商陆根中分离得到的三萜皂苷。
  7. GC13809 Eslicarbazepine acetate

    艾司利卡西平醋酸酯,BIA 2-093

     A sodium channel blocker
  8. GC64673 Etbicyphat

    Trimethylopropane phosphate

     Etbicyphat (Trimethylopropane phosphate) 是一种有效的 GABA(A) 受体竞争性拮抗剂。Etbicyphat 诱导海马体 CA1 神经元的类癫痫样活动，并与 GABA(A)-benzodiazepine 受体结合。
  9. GC74193 Ethaverine hydrochloride Ethaverine hydrochloride罂粟碱的衍生物，抑制心脏L型钙通道。
  10. GC47314 Ethopropazine (hydrochloride)

    盐酸乙丙嗪,Isothazine hydrochloride; Lysivane hydrochloride; Parsidol hydrochloride

     A BChE inhibitor
  11. GC47315 Ethosuximide-d5

    CI-366-d5, NSC 64013-d5

     An internal standard for the quantification of ethosuximide
  12. GC18399 Ethotoin

    乙苯妥英,Peganone

     An anticonvulsant
  13. GC25387 Ethyl (triphenylphosphoranylidene) acetate

    (Carbethoxymethylene)triphenylphosphorane, Triphenylcarbethoxymethylenephosphorane, Ethyl 2-(triphenylphosphoranylidene)acetate

     Ethyl (triphenylphosphoranylidene) acetate (Triphenylcarbethoxymethylenephosphorane, (Carbethoxymethylene)triphenylphosphorane) may act as an inhibitor of cholinesterase that inhibits AChE and BChE.
  14. GC38678 Ethyl Caffeate

    咖啡酸乙酯

     Ethyl caffeate, a naturally occurring compound found in Bidens pilosa, suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2 and PGE2 in vitro.
  15. GC31023 Ethyl dirazepate Ethyldirazepate是一种苯并二氮杂(benzodiazepine)衍生物。具有抗焦虑和催眠特性。
  16. GC63822 Ethyl linolenate

    亚麻酸乙酯

     An esterified form of α-linolenic acid
  17. GC50680 Ethyl LipotF Selective FTO inhibitor (IC50 = 0
  18. GC52303 Ethyl Mycophenolate A potential impurity found in commercial preparations of mycophenolate mofetil
  19. GC43635 Ethyl p-methoxycinnamate

    对甲氧基肉桂酸乙酯

     A natural product with diverse actions
  20. GC90194 Ethyl-β-D-Glucuronide-d5

    Ethyl-β-D-Glucopyranosiduronic Acid-d5, Ethyl-β-D-Glucosiduronic Acid-d5

    一种用于乙基-β-D-葡萄糖醛酸盐定量的内部标准
  21. GC12355 Eticlopride hydrochloride

    依替必利盐酸盐

     A dopamine D2 and D3 receptor antagonist
  22. GC36012 Etifoxine

    艾替伏辛,HOE 36-801

     A positive allosteric modulator of GABAA receptors
  23. GC15264 Etifoxine hydrochloride

    盐酸艾替伏辛,Stresam;HOE 36-801

     A positive allosteric modulator of GABAA receptors
  24. GC47321 Etifoxine-13C-d3

    艾替伏辛 13C-d3

     A neuropeptide with diverse biological activities
  25. GC39757 Etilevodopa hydrochloride

    L-3,4-二羟基苯丙氨酸乙酯盐酸盐,L-DOPA ethyl ester hydrochloride; Levodopa ethyl ester hydrochloride

     Etilevodopa (L-Dopa ethyl ester) hydrochloride 是 Levodopa 的前药，在胃肠道中被非特异性酯酶快速水解为 Levodopa 和乙醇。Etilevodopa hydrochloride 用于治疗帕金森病 (PD)。Levodopa 是多巴胺的直接前体，是一种合适的前体药物，有助于中枢神经系统的渗透和传递多巴胺。
  26. GC49762 Etiocholanedione

    雄甾-3,17-二酮

     A neurosteroid
  27. GC61788 Etiocholanolone

    3a-羟基-5b-雄甾烷-17-酮,5β-Androsterone

     An androgenically inactive metabolite of testosterone and androstenedione
  28. GC16662 Etodolac

    依托度酸; AY-24236

     An NSAID
  29. GC49156 Etodolac Acyl Glucuronide

    依托度酸酰基-Β-D葡糖苷酸

     A phase II metabolite of etodolac
  30. GC47323 Etofenamate-d4

    依托芬那酯 d4

     An internal standard for the quantification of etofenamate
  31. GC10429 Etoricoxib

    依托考昔; MK-0663; L-791456

     A selective COX-2 inhibitor
  32. GC36014 Etoricoxib D4

    依托考昔 D4; MK-0663-d4; L-791456-d4

     Etoricoxib D4 (MK-0663 D4) 是 Etoricoxib 的氘代标记物。Etoricoxib 是一种非甾体抗炎剂，为可口服的、选择性的 COX-2 抑制剂，对人全血 COX-2 和 COX-1 的 IC50 值分别为 1.1 μM 和 116 μM。
  33. GC30910 Eucalyptol (1,8-Cineole)

    NSC 6171

     Eucalyptol是5-HT3受体,钾通道,TNF-α和IL-1β的抑制剂。
  34. GC10089 EUK 134

    乙基双亚氨基甲基愈创木酚锰氯化物

     A synthetic catalase/SOD mimic and hydrogen peroxide scavenger
  35. GC15941 EVP-6124

    EVP 6124;EVP6124

     A partial agonist of α7 subunit-containing nAChRs
  36. GC11091 EVP-6124 hydrochloride

    (R)-7-氯-N-(奎宁环-3-基)苯并[B]噻吩-2-甲酰胺盐酸盐,EVP 6124 hydrochloride;EVP6124 hydrochloride

     A partial agonist of α7 subunit-containing nAChRs
  37. GC91480 Exendin-4 (3-39) amide (trifluoroacetate salt)

    Exendin (3-39)

     Exendin-4 (3-39)酰胺是一种糖肽样肽1受体（GLP-1R）激动剂，也是exendin-4 (48-86)酰胺的活性代谢物。
  38. GC52411 Exendin-4 (5-39) amide (trifluoroacetate salt)

    Exenatide Amide

     An antagonist of the GLP-1 receptor
  39. GC62966 Ezeprogind disulfate Ezeprogind (AZP-2006) disulfate 是一种具有口服活性神经营养诱导剂 (neurotrophic inducer)。Ezeprogind disulfate 针对所有神经退行性变的原因，而不仅仅是针对标记物，如 Abeta 蛋白或 tau 蛋白。Ezeprogind disulfate 是一种有效的神经保护剂 (neuroprotectant)，可用于神经疾病的研究，包括进行性核上麻痹 (PSP)、 Tau 蛋白病变、阿尔茨海默病和帕金森病等。
  40. GC31032 F-15599

    NLX-101

     NLX-101 (F-15599) is a highly selective 5-HT1A receptor biased agonist that mediates antidepressant-like activity in rats via prefrontal cortex 5-HT 1A receptors.
  41. GC62967 F13714 fumarate

    F 14679 fumarate

     F13714 fumarate 是一种选择性 5-HT1A 受体偏向激动剂，在慢性轻度应激小鼠模型中单次给药后具有抗抑郁样特性。
  42. GC39748 Facinicline hydrochloride

    RG3487 hydrochloride

     Facinicline hydrochloride (RG3487 hydrochloride) 是具有口服活性的烟碱 α7 receptor 部分激动剂，对人nAChR 的 Ki 值为 6 nM。Facinicline hydrochloride (RG3487 hydrochloride) 可改善啮齿类动物的认知和感觉运动门控。Facinicline hydrochloride (RG3487 hydrochloride) 对5-HT3 受体 (拮抗剂)的Ki 值为 1.2 nM。
  43. GC70734 Fallypride Fallypride是多巴胺D2/D3受体的强效拮抗剂。
  44. GC73801 Fallypride precursor Fallypride precursor（化合物15）可用于合成Fallypride。
  45. GC17299 Famotidine

    法莫替丁; MK-208

     A histamine H2 receptor antagonist
  46. GC13109 Fananserin

    法南色林,RP 62203

     Fananserin (RP 62203) 是一种口服有效的选择性 5-hydroxytryptamine2 (5-HT2) 受体拮抗剂，对大鼠 5-HT2A 受体的 Ki 值为 0.37 nM。
  47. GC36027 Fanapanel hydrate

    ZK200775 hydrate; MPQX hydrate

     Fanapanel hydrate (ZK200775 hydrate) 是高选择性AMPA拮抗剂。
  48. GC18223 Farampator

    CX-691; Org24448

     A positive allosteric modulator of AMPA receptors
  49. GC62972 FAUC 346 FAUC 346 是具有高度选择性的 D3 部分激动剂 (EC50 = 1.5 nM)，也具有抑制 cocaine-seeking行为的作用。
  50. GC12466 FAUC-365 A dopamine D3 receptor antagonist
  51. GC40190 Febuxostat Acyl Glucuronide

    非布司他杂质

     A metabolite of febuxostat

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