Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for Neuroscience

Cat.No. 产品名称 Information
GC46466 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α
17trifluoromethylphenyl13,14dihydro trinor PGF2α
A prostaglandin F derivative similar to latanoprost free acid
GC46463 17-phenyl trinor Prostaglandin F2α-d4
Bimatoprost (free acid)d4, 17phenyl trinor PGF2αd4
An internal standard for the quantification of bimatoprost (free acid)
GC46462 17-phenyl trinor Prostaglandin F2α isopropyl amide
17-phenyl trinor PGF2α isopropyl amide
A derivative of 17-phenyl trinor PGF_2α ethyl amide
GC46461 17-phenyl trinor Prostaglandin F2α glycinamide methyl ester
17-phenyl trinor PGF2α glycinamide methyl ester
A neuropeptide with diverse biological activities
GC46460 17-phenyl trinor Prostaglandin F2α glycinamide
17-phenyl trinor PGF2α glycinamide
A neuropeptide with diverse biological activities
GC46459 17-phenyl trinor Prostaglandin F2α ethyl amide-d4
Bimatoprost-d4, 15(S)-Bimatoprost-d4, 17-phenyl trinor PGF2α ethyl amide-d4
A neuropeptide with diverse biological activities
GC46458 17-phenyl trinor Prostaglandin F2α dimethyl amide
17-phenyl trinor PGF2α dimethyl amide, Bimatoprost dimethyl amide
An isomer of 17-phenyl trinor prostaglandin F_2α ethyl amide
GC46451 16F16 A PDI inhibitor
GC46437 14-dehydro Zymostenol
Δ8,14-Cholestandienol, Cholesta-8,14-dien-3β-ol
A cholesterol precursor
GC46413 11β-Prostaglandin F2α-d9
9α,11β-PGF2α-d9, 11β-PGF2α-d9, 11-epi PGF2α-d9
A neuropeptide with diverse biological activities
GC46412 11β-Prostaglandin F2α-d4
9α,11βPGF2αd4, 11βPGF2αd4, 11epi PGF2αd4
An internal standard for the quantification of 11β-PGF F_2α
GC46366 1,2,3,4-Tetrahydro-β-carboline
1,2,3,4-四氢-9H-吡啶[3,4-B]并吲哚
A serotonin reuptake inhibitor and metabolite of tryptamine
GC46362 [Sar9, Met(O2)11]-Substance P (trifluoroacetate salt)
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-{Sar}-Leu-MetO2-NH2
A neuropeptide with diverse biological activities
GC46355 (S)-Pramipexole-d5 (hydrochloride)
普拉克索杂质
An internal standard for the quantification of (S)-pramipexole
GC46352 (S)-DO271 An inactive control for DO264
GC46346 (S)-(+)-Clopidogrel-d3 (sulfate) A neuropeptide with diverse biological activities
GC46339 (R)-4-Amino-3-hydroxybutyric Acid
(R)-(-)-4-氨基-3-羟基丁酸
A GABA receptor modulator
GC46305 (±)-Nicotine-d3
(+/-)-氘代甲基-烟碱(甲基-2-(3-吡啶基)吡咯烷丝氨酸BETA-羟基丙氨酸)
An internal standard for the quantification of (±)-nicotine
GC46288 (±)-Epibatidine (hydrochloride)
CMI 545 dihydrochloride
An agonist of α4β2 subunit-containing nAChRs
GC46274 (±)-Baclofen-d4
巴氯芬 d4
An internal standard for the quantification of (±)-baclofen
GC46272 (±)-Asenapine-13C-d3 (hydrochloride) An internal standard for the quantification of (±)-asenapine
GC46248 (-)-Ropivacaine-d7 (hydrochloride)
(S)-Ropivacaine-d7
An internal standard for the quantification of (–)-ropivacaine
GC46246 (-)-Hyoscyamine-d3
L-Hyoscyamine-d3, (S)-Hyoscyamine-d3
A neuropeptide with diverse biological activities
GC19382 Methoctramine (hydrate) A selective muscarinic M₂ receptor antagonist
GC61389 Ziprasidone amino acid
齐拉西酮开环物,氨基酸杂质,Ziprasidone Impurity C; Ziprasidone open ring impurity
Ziprasidoneaminoacid(ZiprasidoneImpurityC)是Ziprasidone的杂质。Ziprasidone是5-HT和多巴胺(dopaminereceptor)受体拮抗剂，具有抗精神病活性。
GC61387 Zamifenacin
UK-76654
A muscarinic M₃ receptor antagonist
GC61382 Xanthoangelol
黄色当归醇
Xanthoangelol, a chalcone found in the roots of Angelica keiskei, is a nonselective monoamine oxidase (MAO) inhibitor and a potent dopamine β-hydroxylase (DBH) inhibitor. It has anti-inflammatory, antibiotic and pro-apoptotic activities.
GC61378 VU0238441 VU0238441 is a pan muscarinic acetylcholine receptor (mAChR) positive allosteric modulator (PAM) with EC50 of 2.1 μM, 2.2 μM, 2.8 μM, 3.2 μM and >10 μM for M5, M3, M2, M1 and M4, respectively.
GC61377 VU0119498
1-(4-溴苄基)吲哚-2,3-二酮
An M₁, M₃, and M₅ muscarinic receptor positive allosteric modulator
GC61371 Veratric acid
藜芦酸
Veratricacid(3,4-Dimethoxybenzoicacid)是从蔬菜和水果中得到的多酚物质，可口服，具有抗氧化、保护心血管和抗炎活性。当细胞受到UVB辐射时，Veratricacid能够减少上调的COX-2表达，降低PGE2和IL-6水平。
GC61367 VAF347 VAF347是一种细胞可渗透且高度亲和力的芳烃受体(AhR)激动剂，可诱导AhR信号传导。VAF347抑制颗粒单核细胞(GM期)前体中CD14+CD11b+单核细胞的发育。VAF347具有抗炎作用。
GC61337 Tolmetin
托麦汀；托美丁
Tolmetin (Tolectin) is a nonsteroidal anti-inflammatory drug of the heterocyclic acetic acid derivative class and also exhibits analgesic and antipyretic activity.
GC61317 Tebanicline dihydrochloride
Ebanicline dihydrochloride; ABT-594 dihydrochloride
Tebaniclinedihydrochloride(Ebaniclinedihydrochloride)是nAChR的调节物，具有有效的口服止痛活性。抑制cytisine与神经元nAChR的结合的Ki值为37pM。
GC61286 SP-8356 SP-8356, an anti-inflammatory synthetic verbenone derivative, is a CD147 inhibitor with respect to its regulation of breast cancer cell behavior and cancer progression.
GC61281 SKF-83566 A dopamine D₁ receptor antagonist
GC61268 SB 243213 A 5-HT_2C receptor inverse agonist
GC61256 Rupatadine D4 fumarate
UR-12592 D4 fumarate
RupatadineD4fumarate(UR-12592D4fumarate)是Rupatadinefumarate的氘代标记物。RupatadineFumarate(UR-12592Fumarate)富马酸盐是PAF/H1受体双抑制剂，Ki值分别为0.55μM和0.1μM。
GC61255 Rubrofusarin triglucoside
红镰霉素三葡萄糖苷
Rubrofusarintriglucoside是一种从决明子种子中分离得到的糖苷化合物，可抑制人单胺氧化酶A(hMAO-A)，IC50为85.5μM。
GC61238 Rehmapicrogenin
地黄苦苷元

Rehmapicrogenin可从Rehmanniaglutinosa的根部分离得到，通过抑制iNOS、COX-2和IL-6表现出有效的抗炎作用。
GC61235 Regaloside B
王百合苷 B
RegalosideB是一种从Liliumlongiflorum中分离出来的苯丙烷。RegalosideB可以抑制iNOS和COX-2的表达，具有抗炎活性。
GC61234 Rebamipide D4
瑞巴派特 D4; OPC12759-d4; Proamipide-d4
An internal standard for the quantification of rebamipide
GC61206 Profenofos
丙溴磷
Profenofos是一种乙酰胆碱酯酶抑制有机磷农药，广泛应用于农田作物、蔬菜和水果作物。
GC61193 Piroxicam D3
吡罗昔康 D3; CP-16171 D3
An internal standard for the quantification of piroxicam
GC61186 Picrotoxinin
木防己苦毒宁
Picrotoxinin是一种来源于天然植物的苦味毒素，存在于一种名为Anamirta cocculus的攀援植物的种子中，是一种氯离子通道阻断剂。Picrotoxinin是一种非竞争性的GABA_A受体拮抗剂，负向调节神经递质γ氨基丁酸（GABA）对GABA_A受体的作用。
GC61180 Phenidone
菲尼酮
Phenidone (1-phenyl-3-pyrazolidinone), a dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LOX), is an organic compound that is primarily used as a photographic developer.
GC61167 Paliperidone palmitate
棕榈酸帕利哌酮,9-Hydroxyrisperidone palmitate
Paliperidone Palmitate (9-hydroxyrisperidone palmitate) is a palmitate ester of paliperidone, which is a dopamine antagonist and 5-HT2A antagonist of the atypical antipsychotic class.
GC61162 Osthenol
7-羟基-8-(3-甲基-2-丁烯)-二氢苯并吡喃,Ostenol
Osthenol(Ostenol)是从独活干根中分离得到的一种前酰化香豆素，是一种可逆的，选择性的竞争性人单胺氧化酶-A(hMAO-A)抑制剂(Ki=0.26µM)。Osthenol对重组hMAO-A具有潜在的选择性抑制作用，IC50为0.74µM，对hMAO-A和hMAO-B表现出较高的选择性指数。
GC61108 Naftidrofuryl oxalate
草酸萘呋胺; Nafronyl oxalate salt
Naftidrofuryloxalate(Nafronyloxalatesalt)是在外周血和脑血管病症如血管扩张药的管理中使用的药物,增加细胞氧化能力,且是一种5-HT2受体拮抗剂。
GC61067 Mirtazapine D3
米氮平 D3; Org3770 D3; 6-Azamianserin D3
An Analytical Reference Material
GC61038 Mefenamic acid D4
甲芬那酸 D4
An internal standard for the quantification of mefenamic acid