Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for Neuroscience

Cat.No. 产品名称 Information
GC10806 Histamine 2HCl

组胺二盐酸盐
A biogenic amine
GC70909 Histamine H4 receptor antagonist-1 Histamine H4 receptor antagonist-1是一种组胺H4受体拮抗剂，提取自专利WO2010108059A1化合物60。
GC17869 Histamine Phosphate

二磷酸组胺; Histamine diphosphate
A biogenic amine
GC68330 Histamine-α,α,β,β-d4 dihydrochloride

Ergamine-α,α,β,β-d4 dihydrochloride
Histamine-α,α,β,β-d4 (Ergamine-α,α,β,β-d4) dihydrochloride 是 Histamine 的氘代物。Histamine是一种参与局部免疫反应的有机含氮化合物, 调节肠道生理功能, 且作为神经递质。
GC40114 Histone H3K4Me3 (1-10) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt) Histone H3K4Me3 (1-10) is an N-terminal peptide fragment of histone H3 that corresponds to amino acid residues 2-11 of the human histone H3 sequence.
GC43858 Histone H3K4Me3 (1-21) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)

ART-K(Me3)-QTARKSTGGKAPRKQLA, H3K4(Me3), Histone H3 (1-21) (Lys4me3), Lys(Me3)4-Histone H3 (1-21)

A peptide fragment of histone H3
GC45480 Histone H3K4Me3 (1-25) amide (human mouse, rat, porcine, bovine) (trifluoroacetate salt)

ART-K(Me3)-QTARKSTGGKAPRKQLATKAA-NH2, Histone H3 (1-25) (Lys4me3), H3K4me3, Lys(Me3)4-Histone H3 (1-25) amide

A peptide fragment of histone H3
GC69234 hMAO-B-IN-4 hMAO-B-IN-4 (compound B10) 是一种选择性的、可逆的、可穿透血脑屏障 (BBB) 的人单胺氧化-B (hMAO-B) 抑制剂，IC50 值和 Ki 值分别为 0.067 和 0.03 μM。hMAO-B-IN-4 抑制 hMAO-A 的 IC50 值为 33.82 μM。hMAO-B-IN-4 可用于阿尔兹海默症和帕金森氏病的研究。
GC72617 hMAO-B-IN-5 hMAO-B-IN-5（B15）是一种强效、选择性和可逆的人单胺氧化酶hMAO-B抑制剂，IC50为0.12μM。
GC48453 Hodgkinsine

(-)-Hodgkinsine
An alkaloid with analgesic activity
GC48454 Hodgkinsine B

(-)-Hodgkinsine B
An alkaloid with analgesic activity
GC17657 Hoechst 34580

HOE 34580;Proamine;Hoechst-34580;Hoechst34580

The nucleic acid stain Hoechst 34580 (Ex/Em: 392/440 nm) is frequently utilized as a cell-permeable nuclear counterstain that emits a blue fluorescence upon binding to dsDNA.
GC36247 Hoechst 34580 tetrahydrochloride

HOE 34580 tetrahydrochloride

Hoechst 34580 tetrahydrochloride是Hoechst系列染料，常用于活细胞的细胞核标记染色。
GC13897 Homatropine Bromide

氢溴酸后马托品
An anticholinergic agent
GC17908 Homatropine Methylbromide

溴甲后马托品,Homatropine methobromide
An anticholinergic agent
GC48897 Homocarnosine

高肌肽; L-Homocarnosine; γ-Aminobutyryl-L-histidine
A dipeptide
GC63950 Homocarnosine TFA

L-Homocarnosine TFA; γ-Aminobutyryl-L-histidine TFA
A dipeptide
GC47435 HPI-1 (hydrate) A Hedgehog pathway inhibitor
GC50260 HS 38 HS 38 是一种有效的、选择性的和 ATP 竞争性的死亡相关蛋白激酶 1 (DAPK1) 和拉链相互作用蛋白激酶 (ZIPK，也称为 DAPK3) 抑制剂，Kd 值分别为 300 nM 和 280 nM。
GC92103 HS-014 (trifluoroacetate salt)

Cyclic [Ac-Cys¹¹, D-Nal¹⁴, Cys¹⁸, Asp-NH₂]-β-MSH(11-22)
HS-014 (trifluoroacetate salt)是黑素皮质素受体4mc4r的拮抗剂；Ki = 3.16 nM。
GC92098 HS-024 (trifluoroacetate salt)

Ac-Cys-Nle-Arg-His-D-Nal-Arg-Trp-Gly-Cys-NH₂; cyclic [AcCys³,Nle⁴,Arg⁵,D-Nal⁷,Cys-NH₂¹¹]α-MSH-(3-11)
HS-024 (trifluoroacetate salt)是黑皮质素受体4的环肽拮抗剂（MC4R；Ki=0.29nM）。
GC72879 HS148 HS148（化合物22）是一种选择性DAPK3抑制剂，Ki值为119 nM。
GC47436 HT-2 Toxin-13C22

HT-2毒素-13C22溶液
An internal standard for the quantification of HT-2 toxin
GC17429 HTMT dimaleate

HTMT马来酸氢盐
A histamine H₁ receptor agonist
GC47437 Humanin (human) (trifluoroacetate salt)

HN
A neuropeptide with diverse biological activities
GC64833 Humulone

律草酮; α-Lupulic acid
Humulone (α-Lupulic acid) 是一种异戊二烯化间苯三酚衍生物，是一种有效的环氧合酶 2 (COX-2) 抑制剂。Humulone 在低微摩尔浓度下作为 GABAA 受体的正调节剂。Humulone 是一种骨吸收抑制剂。Humulone 具有抗氧化、抗血管生成和诱导细胞凋亡的特性。
GC91099 HUP-55
一种脯氨酸内切肽酶抑制剂
GC38793 Huperzine B

石杉碱乙
An alkaloid with neuroprotective activity
GC60913 Huperzine C

石杉碱丙
HuperzineC是从Huperziaserrate中分离的一种生物碱。HuperzineC是一种乙酰胆碱酯酶(AChE)抑制剂，其IC50值为0.6μM。HuperzineC可用于阿尔茨海默症的研究。
GC47440 Hydrocortisone-d4

氘代氢化可的松,Cortisol-d4
An internal standard for the quantification of hydrocortisone
GC43877 Hydroxy Bupropion

羟基1-(3-氯苯基)-2-[(1,1-二甲基乙基)氨基]-1-丙酮盐酸盐,Hydroxy Bupropion
An Analytical Reference Standard
GC43881 Hydroxy Varenicline

伐伦克林杂质
A metabolite of varenicline
GC60915 Hydroxy ziprasidone

齐拉西酮羟基化杂质
Hydroxyziprasidone是Ziprasidone的杂质。Ziprasidone，一种抗精神药物，是5-HT和多巴胺(dopaminereceptor)受体拮抗剂。
GC60917 Hydroxyamine hydrochloride

羟胺盐酸盐
Hydroxylammonium chloride (Hydroxylamine hydrochloride) is the hydrochloric acid salt of hydroxylamine, which is a biological intermediate in the nitrification and in the anammox.
GC47446 Hydroxylupanine

13-羟基羽扇豆鹼,Hydroxylupanine
An alkaloid
GC49559 Hydroxymethyl Tolperisone (hydrochloride) A metabolite of tolperisone
GC15604 Hydroxytacrine (maleate)

马来酸维吖啶,HP 029,1-Hydroxytacrine,P 83-6029A,Velnacrine
A major active metabolite of tacrine
GC16122 Hydroxyzine

羟嗪
A histamine H₁ receptor antagonist
GC10306 Hydroxyzine 2HCl

盐酸羟嗪
A histamine H₁ receptor antagonist
GC36278 Hydroxyzine D4 dihydrochloride

Vistaril-d4' dihydrochloride; Atarax-d4' dihydrochloride
Hydroxyzine D4二盐酸盐是Hydroxyzine氘代化合物标准品。
GC60924 Hydroxyzine D8

安泰乐D8
An internal standard for the quantification of hydroxyzine
GC36279 Hydroxyzine pamoate

双羟萘酸羟嗪；拉姆酸羟嗪；扑姆酸羟嗪；双羟萘酸羟嗪
Hydroxyzine Pamoate is the pamoate salt form of hydroxyzine, a synthetic piperazine histamine H1-receptor antagonist with anti-allergic, antispasmodic, sedative, anti-emetic and anti-anxiety properties.
GC47448 Hydroxyzine-d8 (hydrochloride)

盐酸羟嗪 d8 （双盐酸盐）
An internal standard for the quantification of hydroxyzine
GC11035 Hyoscyamine

L-莨菪碱; Daturine
A muscarinic receptor antagonist
GC49479 Hypoxanthine-d4

次黄嘌呤
An internal standard for the quantification of hypoxanthine
GC70542 HZ166 HZ166是一种GABAA受体亚型选择性苯二氮卓类受体激动剂，对α2-和α3-GABAA受体具有优先活性。
GC31199 Ibodutant (MEN 15596)

MEN 15596
Ibodutant (MEN 15596) (MEN 15596) 是一种有效的选择性速激肽 NK2 受体拮抗剂，pKi 为 10.1。
GC11715 Ibotenic acid

鹅膏氨酸,(RS)-Ibotenic acid; DL-Ibotenic acid
An excitotoxic NMDA and metabotropic glutamate receptor agonist
GC18010 Ibufenac

4-异丁基苯乙酸; Dytransin
A non-selective COX inhibitor
GC17863 Ibuprofen

布洛芬; (±)-Ibuprofen
An NSAID and non-selective COX inhibitor