• 0
    My Cart

    Click Here to Find How Many Items You Have Added:)

qq在线咨询
Home >> Signaling Pathways >> Neuroscience

Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for  Neuroscience

  1. Cat.No. 产品名称 Information
  2. GC40191 Ibuprofen Carboxylic Acid

    羧基布洛芬

     A major metabolite of ibuprofen
  3. GC60926 Ibuprofen impurity 1

    布洛芬杂质

     Ibuprofenimpurity1是Ibuprofen的杂质。Ibuprofen是COX-1和COX-2的抑制剂，IC50值分别为13μM和370μM，具有抗炎的活性。
  4. GC65519 Ibuprofen Impurity F

    布洛芬杂质F

     Ibuprofen Impurity F 是 Ibuprofen 的杂质。Ibuprofen 是 COX-1 和 COX-2 的抑制剂，IC50 值分别为 13 μM 和 370 μM，具有抗炎的活性。
  5. GC16294 Ibuprofen Lysine

    布洛芬赖氨酸盐,(±)-Ibuprofen L-lysine

     Ibuprofen ((±)-Ibuprofen) L-lysine 是一种有效的具有口服活性的选择性 COX-1 抑制剂，IC50 值为 13 μM.
  6. GC66211 Ibuprofen sodium

    (±)-Ibuprofen sodium

     Ibuprofen ((±)-Ibuprofen) sodium 是一种具有口服活性的 COX-1 选择性抑制剂，IC50 值为 13 μM。Ibuprofen sodium 抑制细胞增殖、血管生成，并诱导细胞凋亡 (apoptosis)。Ibuprofen sodium 是一种非甾体抗炎试剂和一氧化氮 (NO) 供体。Ibuprofen sodium 可用于疼痛、肿胀、炎症、感染、免疫学、癌症的研究。
  7. GC30847 IC87201 An inhibitor of the nNOS-PSD-95 protein-protein interaction
  8. GC39293 ICA-27243 ICA-27243, a selective activator of the neuronal M current and KCNQ2/Q3 channels, induces a concentration-dependent increase in a 86Rb+ efflux from CHO cells expressing KCNQ2/Q3 channels with EC50 of 0.2 μM.
  9. GC16162 ICI 162,846

    histamine H2 receptor antagonist
  10. GC36291 Idalopirdine

    Lu AE58054

     A 5-HT6 receptor antagonist
  11. GC43891 IDFP

    Isopropyl Dodecylfluorophosphonate

     An MAGL and FAAH inhibitor
  12. GC12198 IEM 1754 dihydrobroMide

    IEM 1754 dihydrobroMide 是一种双阳离子金刚烷衍生物，是天然离子型谷氨酸受体开放通道的有效阻断剂，包括昆虫肌肉中的 quisqualate 敏感受体、培养的大鼠皮质神经元中的 NMDAR 和新鲜分离的海马细胞中的 AMPAR。
  13. GC63015 Iferanserin

    S-MPEC

     Iferanserin (S-MPEC) 是一种对 5-HT2A 受体具有亲和力的选择性 5-HT 受体拮抗剂。Iferanserin 可用于内痔疾病的研究。
  14. GC17419 Iguratimod

    艾拉莫德; T614

     A DMARD and COX-2 inhibitor
  15. GC15463 Iloperidone

    伊潘立酮; HP 873

     An atypical antipsychotic
  16. GC10799 Iloperidone hydrochloride

    盐酸伊潘立酮; HP 873 hydrochloride

     An atypical antipsychotic
  17. GC43896 Iloperidone metabolite P95

    伊潘立酮代谢物P95

     A metabolite of iloperidone
  18. GC52147 Iloperidone-d3

    伊潘立酮 d3

     An internal standard for the quantification of iloperidone
  19. GC49359 IM-156 (acetate)

    HL156A, HL271

     A mitochondrial complex I inhibitor and an AMPKα activator
  20. GC11220 Imetit dihydrobromide

    S-[2-(4(5)-咪唑基)乙基]异硫脲氢溴酸盐,VUF 8325 dihydrobromide; SKF 91105 dihydrobromide

    A histamine H3 and H4 receptor agonist
  21. GC52251 Imidacloprid Impurity 1 A potential impurity in commercial preparations of imidacloprid
  22. GC30812 Imidafenacin (KRP-197)

    咪达那新; KRP-197; ONO-8025

     Imidafenacin (KRP-197, ONO-8025) is a urinary antispasmodic of the anticholinergic class. It is a novel antimuscarinic agent with safety and efficacy, has been clinically used for the treatment of overactive bladder. Imidafenacin(KRP-197; ONO-8025) is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM; less potent for M2 receptors(IC50=4.13 nM). IC50 value: 0.3 nM(M3).
  23. GC12885 Imipramine (hydrochloride)

    盐酸丙咪嗪

     A tricyclic antidepressant
  24. GC65209 Imipramine-d4 hydrochloride

    盐酸丙咪嗪 d4 (盐酸盐)

     Imipramine-d4 hydrochloride 是 Imipramine hydrochloride 的氘代物。Imipramine hydrochloride 抑制血清素转运蛋白(serotonin)，IC50 值为 32 nM。Imipramine hydrochloride 可阻止胰酶的易位，抑制 MV 和外泌体的分泌。
  25. GC12966 Immepip dihydrobromide

    4-(1H-咪唑基-4-甲基)哌啶二氢溴酸盐

     A histamine H3 receptor agonist
  26. GC14260 Immethridine dihydrobromide A potent histamine H3 receptor agonist
  27. GC10241 Impentamine dihydrobromide histamine H3 receptor antagonist
  28. GN10437 Imperatorin

    欧前胡素; Ammidin

     A furanocoumarin with diverse biological activities
  29. GC36305 Imrecoxib

    艾瑞昔布; BAP-909

     Imrecoxib（BAP-909）艾瑞昔布是选择性环氧合酶 2 (COX-2) 抑制剂，IC50 值为 18 nM，也可以抑制 COX1 活性，IC50 值为 115 nM。Imrecoxib（BAP-909) 艾瑞昔布具有抗炎作用。
  30. GC47454 IMS 2186 An anti-choroidal neovascularization agent
  31. GC70613 Inaperisone Inaperisone是一种中枢作用的肌肉松弛剂。
  32. GC65937 INCB38579 INCB38579 是一种具有口服活性、高度脑穿透和选择性的组胺 H4 受体 (HH4R) 拮抗剂 (hH4R IC50=4.8 nM, mH4R IC50=42 nM, rH4R IC50=32 nM)。INCB38579 具有抗炎和抗瘙痒的活性。
  33. GC14093 Indatraline hydrochloride

    茚达曲林盐酸盐; Lu 19-005

     Indatraline hydrochloride (Lu 19-005) 是一种非选择性单胺转运蛋白抑制剂，可阻断神经递质（多巴胺、血清素和去甲肾上腺素）的再摄取，其功效与可卡因相似。
  34. GC70778 Indazole-Cl Indazole-Cl（Ind-Cl）是一种具有炎症作用的雌激素受体（ER）-β特异性激动剂。
  35. GC36314 Indobufen

    吲哚布芬; Ibustrin

     Indobufen (Ibustrin, K 3920) is a reversible platelet aggregation inhibitor. Indobufen is a reversible inhibitor of platelet cyclooxygenase (Cox) activity and suppresses thromboxane synthesis.
  36. GC39848 Indole-2-carboxylic acid

    2-吲哚甲酸

     Indole-2-carboxylic acid is a strong inhibitor of lipid peroxidation.
  37. GC47456 Indole-3-pyruvic Acid

    吲哚-3-丙酮酸

     An endogenous metabolite of tryptophan
  38. GC17556 Indomethacin

    吲哚美辛; Indometacin

     Indomethacin(吲哚美辛)是一种有效的口服活性 COX1/2 抑制剂,COX-1 和 COX-2 的IC50 值分别为 18 nM 和 26 nM。
  39. GC49698 Indomethacin Acyl Glucuronide

    (吲哚美辛酰基)-Β-D-葡糖苷酸

     A metabolite of indomethacin
  40. GC12719 Indomethacin heptyl ester A potent, non-selective COX-2 inhibitor
  41. GC14777 Indomethacin N-octyl amide Indomethacin with enhanced selectivity for COX-2
  42. GC60935 Indomethacin sodium hydrate

    吲哚美辛钠盐三水合物; Indometacin sodium hydrate

     A non-selective COX inhibitor
  43. GC40227 Indomethacin-d4

    吲哚美辛-D4; Indometacin-d4

     An internal standard for the quantification of indomethacin
  44. GC68423 Indomethacin-d4 Methyl Ester

    吲哚美辛甲酯 d4

     Indomethacin-d4 Methyl Ester 是 Indomethacin 的氘代物。Indomethacin (Indometacin) 是一种有效的，可透过血脑屏障的，非选择性的 COX1 和 COX2 抑制剂，在 CHO 细胞中，对人 COX-1 和 COX-2 的 IC50 值分别为 18 nM 和 26 nM。Indomethacin 通过干扰溶酶体的正常功能来破坏自噬流 (autophagic flux)。
  45. GC61565 Indophagolin

    5-溴-N-(4-氯-3-(三氟甲基)苯基)-1-(环丙烷羰基)吲哚啉-6-磺酰胺

     Indophagolin, a potent indoline-containing autophagy inhibitor with IC50 of 140 nM, antagonizes the purinergic receptor P2X4 as well as P2X1 and P2X3 with IC50s of 2.71, 2.40 and 3.49 μM, respectively, also has a strong antagonistic effect on serotonin receptor 5-HT6 with IC50 of 1.0 μM.
  46. GC52154 Inflammasome Inhibitor 4b An inhibitor of NLRP3 inflammasome activation
  47. GC48621 INNO-8875

    INO-8875

     An adenosine A1 receptor agonist
  48. GC13042 Inotilone

    (2E)-2-[(3,4-二羟基苯基)亚甲基]-5-甲基-3(2H)-呋喃酮

     A COX-2 inhibitor
  49. GC33861 Inulicin (1-O-Acetylbritannilactone)

    旋覆花内酯,1-O-Acetylbritannilactone

     A sesquiterpene lactone with diverse biological activities
  50. GC12265 Iodophenpropit dihydrobromide A histamine H3 receptor antagonist
  51. GC73024 IONIS-MAPTRx sodium

    BIIB080 sodium; ISIS 814907 sodium

     IONIS-MAPTRx sodium是首个降低tau蛋白的反义寡核苷酸（ASO）。

Items 2001 to 2050 of 3961 total

per page
  2. 39
  3. 40
  4. 41
  5. 42
  6. 43

Set Descending Direction