Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for Neuroscience

Cat.No. 产品名称 Information
GC35381 Arborine
山柑子碱
Arborine 可从 Glycosmis arborea 中分离。Arborine 抑制乙酰胆碱的外周作用并诱导血压下降。
GC35334 Amyloid β Peptide (42-1)(human)
淀粉Β-蛋白(42-1),Amyloid β Peptide (42-1)(human)
淀粉样蛋白 β Peptide (42-1)(human) 是淀粉样蛋白 β 的无活性形式；肽 (1-42)。
GC35323 Amisulpride hydrochloride
氨磺必利盐酸盐; DAN 2163 hydrochloride
A dopamine D₂ and D₃ and 5-HT_2B, 5-HT₇, and 5-HT_7A receptor antagonist
GC35303 Alosetron D3 Hydrochloride
GR-68755C D3
Alosetron D3 Hydrochloride (GR-68755C D3) 是Alosetron氘代化合物标准品。
GC35302 Alosetron (Hydrochloride(1:X))
盐酸阿洛司琼,GR 68755 (Hydrochloride(1
A 5-HT₃ receptor antagonist
GC35301 Alosetron ((Z)-2-butenedioate)
马来酸阿洛司琼; GR 68755 ((Z)-2-butenedioate); GR 68755X ((Z)-2-butenedioate)
Alosetron (Z)-2-butenedioate (GR 68755 (Z)-2-butenedioate) 是5-HT3受体拮抗剂，可作用于肠易激综合征。
GC35299 Aloeresin D
芦荟新苷 D
Aloeresin D 是从芦荟中分离得到的色原酮苷，可抑制 β-分泌酶 (BACE1) 活性，IC50 值为 39 μM。
GC35284 Alimemazine D6
阿利马嗪D6,Trimeprazine D6
Alimemazine D6是Alimemazine氘代化合物标准品。
GC35279 Aldicarb sulfone
涕灭威砜
A metabolite of aldicarb
GC35272 Ajmalicine
萝巴新,Raubasine
A terpenoid indole alkaloid
GC35270 Agomelatine L(+)-Tartaric acid
阿戈美拉汀 L(+)-酒石酸; S-20098 L(+)-Tartaric acid
Agomelatine（L(+)-酒石酸）可抗抑郁，是一种去甲肾上腺素-多巴胺抑制解除剂（NDDI），能拮抗5-HT2C受体。
GC35269 Agomelatine hydrochloride
维度新; S-20098 hydrochloride
A melatonin receptor agonist and 5-HT_2B and 5-HT_2C antagonist
GC35256 Adrenomedullin (11-50), rat A truncated form of rat adrenomedullin
GC35252 Adoprazine
阿哆嗪; SLV313
Adoprazine是5-HT1A受体的完全激动剂和D2/3受体的拮抗剂。
GC35236 Acetylshikonin
乙酰紫草素
Acetylshikonin，来源于紫草根，具有抗癌、抗炎作用。Acetylshikonin 是一种非选择性的细胞色素 P450 抑制剂，对所有 P450 亚型抑制的 IC50 值范围为 1.4-4.0 μM。Acetylshikonin 是一种 AChE 抑制剂，具有很强的抗凋亡活性。
GC35222 ABT-239 ABT-239 是一种新颖的，高效的，非咪唑类的 H3R 拮抗剂，也是 TRPV1 的拮抗剂。
GC35192 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone
3,4-二氢-7-羟基-2(1H)-喹啉酮,3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
7-Hydroxy-3,4-dihydrocarbostyril is used as the materials for the organic synthesis intermediates.
GC35027 [Sar9] Substance P [Sar9] Substance P 是一种有效的选择性神经激肽 (NK)-1 受体激动剂。
GC35019 [Nle11]-Substance P [Nle11]-Substance P 是物质 P 类似物，避免了甲硫氨酸氧化问题。
GC35013 [8]-Shogaol
8-姜烯酚
[8]-Shogaol，生姜中的一种刺激性酚类化合物，具有抗血小板活性 (IC50=5 μM) 和抑制 COX-2 (IC50=17.5 μM)。[8]-Shogaol 诱导人白血病细胞凋亡。
GC35012 [10]-Shogaol
10-姜烯酚
A phenol with diverse biological activities
GC35011 (Z)-Thiothixene
替沃噻吨
(Z)-Thiothixene 是 serotonergic receptor 的拮抗剂，来自专利 US 20150141345 A1。
GC35006 (S)-Rasagiline mesylate
(S)-雷沙吉兰甲磺酸; TVP1022 mesylate; S-PAI mesylate
(S)-Rasagiline (TVP1022) 甲磺酸盐是S-构型Rasagiline，对MAO-B的活性弱。
GC34998 (S)-(-)-5-Fluorowillardiine hydrochloride
(5S)-Fluorowillardiine hydrochloride; (S)-5-Fluorowillardiine hydrochloride
(S)-(-)-5-Fluorowillardiine hydrochloride 是AMPAR高效选择性激动剂。
GC34995 (R,R)-Palonosetron Hydrochloride
(R,R)-盐酸帕洛诺司琼
(R,R)-Palonosetron Hydrochloride 是一个有活性的 Palonosetron 对映异构体。
GC34993 (R)-Rivastigmine D6 tartrate
酒石酸卡巴拉汀 D6
An internal standard for the quantification of rivastigmine
GC34986 (R)-Baclofen hydrochloride
(R)-巴氯芬盐酸盐; Arbaclofen hydrochloride; STX 209 hydrochloride
A GABA_B receptor agonist
GC34959 (+)-Sparteine
(+)-鹰爪豆碱
A quinolizidine alkaloid
GC34957 (+)-Cevimeline hydrochloride hemihydrate
(-)-SNI-2011; (-)-AF102B hydrochloride hemihydrate
(_addition_)-Cevimeline盐酸水合物是mAChR激动剂。
GC34954 (+)-Borneol
(+)-冰片
A bicyclic monoterpene with diverse biological activities
GC34949 (-)-Isocorypalmine
(-)-异延胡索单酚碱,Tetrahydrocolumbamine; (S)-Tetrahydrocolumbamine
An isoquinoline alkaloid and metabolite of L-THP with diverse biological activities
GC34947 (-)-Corynoxidine
延胡索乙素N氧化物

(-)-Corynoxidine 分离自延胡索 Corydalis speciosa，是一种乙酰胆碱酯酶 acetylcholinesterase 抑制剂，IC50 值为 89.0 μM。(-)-Corynoxidine 对金黄色葡萄球菌和耐甲氧西林金黄色葡萄球菌菌株有不同程度的抗菌活性。
GC45263 (+)-D-threo-PDMP (hydrochloride)
D-PDMP
An inhibitor of sphingolipid biosynthesis
GC45250 (-)-L-threo-PDMP (hydrochloride) An enhancer of ganglioside biosynthesis
GC45244 (-)-(α)-Kainic Acid (hydrate)
红藻氨酸

An L-glutamate analog with neuroexcitatory activities
GC45242 ω-Conotoxin MVIIC (trifluoroacetate salt)
SNX-230
An N-, P-, and Q-type calcium channel blocker
GC45241 ω-Conotoxin GVIA (trifluoroacetate salt) ω-Conotoxin GVIA is a peptide originally isolated from the marine mollusk C.
GC45240 ω-Agatoxin IVA (trifluoroacetate salt)
ω-Aga IVa, SNX-290
A P-type calcium channel blocker
GC45236 β-Endorphin (rat)
Β-内啡肽,鼠
An opioid neuropeptide
GC45234 β-Endorphin (1-27) (human) (trifluoroacetate salt) An endogenous opioid peptide
GC45233 β-Endorphin (1-26) (human) (trifluoroacetate salt) A neuropeptide
GC45198 α-CGRP (8-37) (human) (trifluoroacetate salt)
Calcitonin Gene-Related Peptide-1 (8-37) (human), CGRP-1 (8-37) (human), α-Calcitonin Gene-Related Peptide (8-37) (human)
An antagonist of CGRP receptors
GC45196 α-Bungarotoxin (trifluoroacetate salt)
A neurotoxin that blocks nAChR
GC45188 Zuclopenthixol
珠氯噻醇,(Z)-Clopenthixol
A dopamine receptor antagonist
GC45183 ZK118182 isopropyl ester The prodrug form of a potent DP receptor agonist
GC45180 Ziconotide (trifluoroacetate salt)
ωConotoxin MVIIA, SNX-111
A synthetic peptide blocker of N-type calcium channels
GC45175 YVAD-CHO (trifluoroacetate salt)
H-Tyr-Val-Ala-Asp-CHO
A caspase-1/ICE inhibitor
GC45159 WOBE437 A potent endocannabinoid uptake inhibitor
GC45158 Withanolide B
睡茄素B
A withanolide
GC45157 WAY-161503
WAY161503盐酸盐
A 5-HT_2C receptor agonist