Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for Neuroscience

Cat.No. 产品名称 Information
GC43734 Ganglioside GQ1b Mixture (sodium salt)

神经节苷脂GQ1B四钠盐

A mixture of ganglioside G_Q1b
GC52505 Ganglioside GT1b (bovine) (sodium salt)

Ganglioside G1, Trisialoganglioside GT1b
A sphingolipid
GC43735 Ganglioside GT1b Mixture (sodium salt)

三唾液酸神经节甘酯GT1B,Ganglioside G1 Mixture
A sphingolipid
GC69150 Gantenerumab

更汀芦单抗
Gantenerumab 是一种完全人源的抗淀粉样蛋白-β (Aβ) IgG1 单克隆抗体，显示出持续的脑淀粉样蛋白-β 结合。Gantenerumab 可用于阿尔茨海默病研究。
GP10107 Gap 26

Val-Cys-Tyr-Asp-Lys-Ser-Phe-Pro-Ile-Ser-His-Val-Arg
Gap 26，作为一种模拟连接蛋白的肽，含有对连接子对接生成间隙连接至关重要的SHVR氨基酸区域。
GC60866 Gap 26 TFA Gap 26, a connexin mimetic peptide that composeds of residue no. 63-75 of the extracellular loop 1 of connexin 43 (Cx43), is a gap junction inhibitor. Gap 26 blocks photoliberating inositol-1,4,5-trisphosphate triggers ATP release.
GP10119 Gap 27

Ser-Arg-Pro-Thr-Glu-Lys-Thr-Ile-Phe-Ile-Ile

A connexin-mimetic peptide
GC49416 Gap 27 (trifluoroacetate salt)

43Gap27, SRPTEKTIFII
A connexin-mimetic peptide
GC17681 Gap19 Gap19 (KQIEIKKFK) 阻断 HC 但不阻断 GJC，并且特定于 Cx43。
GC48343 Gap19 (trifluoroacetate salt)

KQIEIKKFK
An inhibitor of Cx43 hemichannels
GC13474 Garcinol

山竹子素

Garcinol是组蛋白乙酰转移酶p300和PCAF的非特异性抑制剂，IC₅₀分别为7μM和5μM。
GC15133 Gastrin I (human)

胃膜素
Gastrin I (human) 是存在于胃内的内源性肽，作用于缩胆囊素受体2，促进胃酸分泌。
GA21898 Gastrin I (rat)

胃泌素,鼠,Rat Gastrin-17
胃泌素I（大鼠）（Rat Gastrin-17）是一种肽类激素，能有效刺激胃酸分泌。
GC30680 Gastrin/CCK antagonist 1
Gastrin/CCKantagonist1是gastrin/CCK的拮抗剂，可用于肠胃失调疾病的研究。
GC43738 GAT211 A CB₁ receptor agonist and PAM
GC43740 GAT229 A positive allosteric modulator of the CB₁ receptor
GC12456 GBR 12783 dihydrochloride GBR 12783 dihydrochloride 是一种特异性、有效和选择性的多巴胺摄取抑制剂，抑制大鼠和小鼠纹状体突触体对 [3H] 多巴胺的摄取，IC50 分别为 1.8 nM 和 1.2 nM。
GC36126 GBR 12935

(DIPHENYLMETHOXY)GBR-12935,1-(2-乙基)-4-(3-苯丙基)哌嗪
An inhibitor of dopamine uptake
GC13853 GBR 12935 dihydrochloride An inhibitor of dopamine uptake
GC12179 GBR 13069 dihydrochloride dopamine uptake inhibitor
GC38529 Geissoschizine methyl ether

缝籽木嗪甲醚
Geissoschizine methyl ether，一种 Uncaria hook 发现的生物碱类化合物，也是具有精神药物作用的 Yokukansan 的主要活性成分。Geissoschizine methyl ether 是有效的 5-HT1A 受体的激动剂。
GN10428 Geniposide

栀子苷

An iridoid glycoside with diverse biological activities
GC70532 Gepirone-d8 Gepirone-d8是氘标记的吉皮隆。
GC47400 GGTI 2133 (trifluoroacetate salt) A geranylgeranyl transferase I inhibitor
GC43752 Ghrelin (rat) (acetyl) (trifluoroacetate salt) An acetylated form of ghrelin
GC43753 Ghrelin (rat) (palmitoyl) (trifluoroacetate salt) A palmitoylated form of ghrelin
GC45803 GHRP-2 (trifluoroacetate salt)

D-Ala-3-(2-naphthalenyl)-D-Ala-L-Ala-L-Trp-D-Phe-L-lysinamide, Growth Hormone-Releasing Peptide 2, KP-102, Pralmorelin
A neuropeptide with diverse biological activities
GC45459 GHRP-6 (acetate)

生长激素释放肽-6
A growth hormone secretagogue and GHS-R agonist
GC31592 GI 181771 GI181771是研究用于治疗肥胖症的胆囊收缩素1(cholecystokinin1)受体激动剂。
GC69161 Gidazepam

Gidasepam; Hidazepam; Hydazepam
Gidazepam 是一种 GABA 受体通道 (GABA RCs) 激动剂。
GN10251 Ginkgolide A

银杏内酯A; BN-52020
A terpenoid lactone with diverse biological activities
GC20007 Ginsenoside CK

20(S)-人参皂苷 C-K; Compound K
Ginsenoside CK，一种由主要人参皂苷化合物转化而来的次级人参皂苷，比其母体人参皂苷具有更高的生物利用度和溶解性，具有极其重要的意义。
GN10220 Ginsenoside Rb3

人参皂苷 Rb3; Gypenoside IV
A steroid glycoside with diverse biological activities
GN10254 Ginsenoside Rc

人参皂苷 Rc; Panaxoside Rc
A saponin with diverse biological activities
GN10549 Ginsenoside Rd

人参皂苷 Rd; Gypenoside VIII
A natural steroid glycoside with diverse effects
GN10307 Ginsenoside Re

人参皂苷 Re; Ginsenoside B2; Panaxoside Re; Sanchinoside Re
A natural steroid glycoside with diverse effects
GN10544 Ginsenoside Rg1

人参皂苷 Rg1; Panaxoside A; Panaxoside Rg1
人参皂苷Rg1是人参的主要活性成分之一，是一种具有多种生物活性的甾体糖苷。人参皂苷Rg1可降低大脑Aβ 水平并减少 NF-κB 核转移。
GN10614 Ginsenoside Rg2

人参皂苷 Rg2; Chikusetsusaponin I; Panaxoside Rg2; Prosapogenin C2
A natural steroid glycoside with diverse effects
GC31706 Ginsenoside Rg5

人参皂甙 Rg5
A ginsenoside with diverse biological activities
GC60875 GKT136901

NOX Inhibitor IV
A dual inhibitor of NOX1 and NOX4
GC36145 Glabrolide

甘草内酯
Glabrolide，来源于 Glycyrrhiza uralensis Fisch.，是一种 β 分泌脢 1 (BACE-1) 抑制剂。
GC41486 Glaucine

海罌粟鹼,O,O-Dimethylisoboldine; S-(+)-Glaucine; NSC 34396
An Analytical Reference Standard
GC65609 Glicoricone Glicoricone 是一种从甘草中分离出来的酚类化合物。Glicoricone 是单胺氧化酶 (MAO) 的抑制剂，IC50 为 140 μM。Glicoricone 可与雌激素受体 (ER) 结合并显示出雌激素拮抗剂活性。
GC52492 Globotriaosylceramide (hydroxy) (porcine RBC)

Ceramide Trihexosides (bottom spot) (porcine)
A sphingolipid
GC52491 Globotriaosylceramide (non-hydroxy) (porcine RBC)

Ceramide Trihexosides (top spot) (porcine)
A sphingolipid
GC43758 Globotriaosylceramides (hydroxy) (porcine) Globotriaosycleramides are glycosphingolipids found in mammalian cell membranes that are synthesized from lactosylceramides.
GC43760 Globotriaosylceramides (porcine)

球形三酰神经
A sphingolipid
GC92119 GLP-1 (7-36) acid (human, mouse, rat, porcine, bovine)

Glucagon-like Peptide 1 (7-36) acid
GLP-1 (7-36) acid (human, mouse, rat, porcine, bovine)是激素和GLP-1受体（GLP-1R）激动剂GLP-1（7-36）酰胺的衍生物。
GC45464 GLP-2 (rat) (trifluoroacetate salt)

Glucagon-like Peptide 2
A gut peptide hormone antagonist of GLP-2R
GC18387 Glucocerebrosides

葡萄糖脑苷脂
A sphingolipid