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Home >> Signaling Pathways >> Neuroscience

Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for  Neuroscience

  1. Cat.No. 产品名称 Information
  2. GC16881 FR 122047 hydrochloride

    1-[[4,5-双(4-甲氧基苯基)-2-噻唑]羰基]-4-甲基哌嗪盐酸盐

     A selective COX-1 inhibitor
  3. GC33893 FR-188582 FR-188582是高选择性的环氧合酶(COX-2)抑制剂，IC50值为17nM。
  4. GC13132 FR122047 (hydrate) selective inhibitor of COX-1
  5. GC66408 Fremanezumab

    TEV-48125

     Fremanezumab (TEV-48125) 是一种人源化 IgG2a 单克隆抗体，可选择性且有效地与降钙素基因相关肽 (CGRP) 结合。CGRP 是一种 37 个氨基酸的神经肽，参与偏头痛的中枢和外周病理生理事件。Fremanezumab 具有用于慢性偏头痛研究的潜力。
  6. GC36076 Frentizole

    夫仑替唑

     Frentizole (Frentizol) is a novel inhibitor of amyloid beta peptide (Abeta) binding alcohol dehydrogenase (ABAD) interaction with IC50 of 200 μM. Frentizole is a nontoxic antiviral and immunosuppressive agent used clinically in rheumatoid arthritis and systemic lupus erythematosus.
  7. GC32050 FRG8701 FRG-8701是一种新组氨酸H2-receptor拮抗剂，IC50值为0.25至0.43μM。
  8. GC25434 Frovatriptan Succinate

    SB 209509 Succinate,VML 251 Succinate

     Frovatriptan Succinate(SB 209509 Succinate,VML 251 Succinate) is the succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity especially for the 5-HT1B/1D receptors.
  9. GC38781 Frovatriptan succinate hydrate

    罗曲普坦琥珀酸盐,(R)-Frovatriptan succinate hydrate; SB 209509 succinate hydrate; VML 251 succinate hydrate

     An agonist of 5-HT1B and 5-HT1D receptors
  10. GC43700 FSB A fluorescent probe
  11. GC52483 Fucosylated Ganglioside GM1 (porcine) (ammonium salt)

    Fucosylated Monosialoganglioside GM1, Fucosyl GM1

     A sphingolipid
  12. GC43708 Fulvic Acid

    富里酸

     A fungal metabolite
  13. GC52047 Fustin

    黄颜木素,(±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone

     A flavanone with diverse biological activities
  14. GC41534 FzM1

    Frizzled M1

     An allosteric ligand of Frizzled4
  15. GC11385 G-Protein antagonist peptide G-蛋白拮抗肽是抑制G蛋白与其受体结合的P物质相关肽。
  16. GC63766 G-Protein antagonist peptide TFA G-Protein antagonist peptide TFA 是一种截短的 substance P 相关肽，与受体竞争 G 蛋白结合。G-Protein antagonist peptide TFA 抑制重组磷脂囊泡中 M2 毒蕈碱胆碱能受体 (M2 mAChR) 激活 Gi 或 Go 或 β 肾上腺素能受体激活 Gs。
  17. GC60862 GABAA receptor agent 1

    2-(4-氯苯基)-6-硝基-1H-苯并[D]咪唑

     GABAA receptor agent 1 is a high affinity ligand for Gamma-aminobutyric acid A (GABAA) receptor that exerts potent anticonvulsant activity.
  18. GC18336 Gabaculine (hydrochloride)

    格巴库林盐酸盐

     An irreversible inhibitor of GABA-T
  19. GC12714 Gabapentin

    加巴喷丁

     An approved antiepileptic drug
  20. GC47388 Gabapentin-d4

    加巴喷丁 d4

     An internal standard for the quantification of gabapentin
  21. GC18469 Galactosylcerebrosides (bovine)

    半乳糖苷神经酰胺

     A sphingolipid
  22. GC43721 Galactosylcerebrosides (hydroxy)

    Cerebrosides; Phrenosin (bottom spot)

     A mixture of isolated bovine hydroxy galactosylceramides
  23. GC43722 Galactosylcerebrosides (non-hydroxy)

    猪脑苷脂

     A sphingolipid
  24. GC43723 Galactosylsphingosine (d18:1)

    神经鞘氨醇半乳糖苷,Galactosylsphingosine

     A bioactive sphingolipid
  25. GC49154 Galanin (2-11) amide (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)

    AR-M1896, Gal(2-11)-NH2, WTLNSAGYLL-NH2

     A synthetic peptide fragment of galanin and an agonist of the GAL2 receptor
  26. GC48326 Galanin (Human) (Acetate)

    GAL (human), Galanin (1-30)

     A neuropeptide and GAL receptor agonist
  27. GC43724 Galanin (rat, mouse) (trifluoroacetate salt)

    GAL (rat, mouse)

     A neuropeptide with diverse biological activities
  28. GC52078 Galantamine (hydrobromide)

    氢溴酸加兰他敏

    An alkaloid with AChE inhibitory and nAChR potentiating activities
  29. GC47389 Galantamine-d3 (hydrobromide) An internal standard for the quantification of galantamine
  30. GC16573 Galanthamine

    加兰他敏; Galantamine

     An alkaloid with AChE inhibitory and nAChR potentiating activities
  31. GC14624 Galanthamine HBr

    氢溴酸加兰他敏

     An alkaloid with AChE inhibitory and nAChR potentiating activities
  32. GC36103 Galanthamine hydrobromide Galanthamine氢溴酸盐是长效的中心活性的乙酰胆碱酯酶（AChE）抑制剂，IC50为410 nM，同时是神经元烟碱乙酰胆碱受体的变构增强剂。
  33. GC64492 Galanthamine N-Oxide

    加兰他明 N-氧化物

     Galanthamine N-Oxide 是一种生物碱，分离于 Zephyranthes concolor 的球茎中。Galanthamine N-Oxide 抑制电鳗乙酰胆碱酯酶 (AChE)，EC50 为 26.2 μM。Galanthamine N-Oxide 是TcAChE，hAChE 和 hBChE 酶活性位点中底物调节的显著抑制剂。
  34. GC36104 Galanthaminone

    氢溴酸加兰他敏,(-)-Narwedine; Narwedin

     Galanthaminone是竞争性可逆的胆碱酯酶（AChE）抑制剂，可作用于多种记忆障碍疾病。
  35. GC66402 Galcanezumab

    LY 2951742

     Galcanezumab (LY 2951742) 是一种针对 CGRP 配体的人源化 IgG4 单克隆抗体。Galcanezumab 可用于偏头痛或丛集性头痛的研究。
  36. GC10972 Gallamine Triethiodide

    三碘季胺酚

     An allosteric modulator of muscarinic acetylcholine receptors
  37. GN10388 Gallic acid

    没食子酸; 3,4,5-Trihydroxybenzoic acid

     A phenol with diverse biological activities
  38. GC61436 Gallic acid hydrate

    没食子酸-水合物; 3,4,5-Trihydroxybenzoic acid hydrate

     A phenol with diverse biological activities
  39. GC43726 Gallotannin

    单宁酸

     单宁酸（Gallotannin；Tannic acid）是一种天然多酚化合物，已在各种植物中发现，具有抗氧化、抗炎、抗血管生成、抗病毒和抗肿瘤等生物活性。Gallotannin抑制DNA聚合酶α、β和κ的活性，IC50值分别为13、130和30nM。
  40. GC47390 Galnon (trifluoroacetate salt)

    Fmoc-β-Cha-Lys-AMC

     A galanin receptor agonist
  41. GC38227 Gamma-Mangostin

    γ-倒捻子素,γ-Mangostin

     A xanthone with diverse biological activities
  42. GC36110 gamma-Secretase Modulators

    (E)-(4R,9AS)-7-[3-甲氧基-4-(4-甲基-1H-咪唑-1-基)苯亚甲基]-4-(3,4,5-三氟苯基六氢吡啶并[2,1-C][1,4]嗪-6-酮,Amyloid-β production inhibitor; γ-Secretase Modulators

     gamma-Secretase Modulators (Amyloid-β production inhibitor)是淀粉状蛋白β生成抑制剂，可作用于阿尔茨海默病。
  43. GC43727 Ganglioside GD1a mixture (sodium salt)

    双唾液酸神经节苷酯GD1A,Ganglioside B1

     A mixture of ganglioside GD1a
  44. GC43728 Ganglioside GD1b Mixture (sodium salt)

    双唾液酸神经节苷酯GD1B

     A sphingolipid
  45. GC43729 Ganglioside GD3 Mixture (sodium salt)

    双唾液酸神经节苷脂GD3; Disialosyllactosylceramide

     A mixture of ganglioside GD3
  46. GC43730 Ganglioside GM1 Asialo Mixture

    神经节苷脂

     A sphingolipid
  47. GC47392 Ganglioside GM1 Mixture (ovine) (ammonium salt)

    GM1, Monosialoganglioside GM1

     A sphingolipid
  48. GC47393 Ganglioside GM1 Mixture (porcine brain) (ammonium salt)

    GM1, Monosialoganglioside GM1

     A sphingolipid
  49. GC43731 Ganglioside GM2 Asialo Mixture

    神经节苷脂

     A sphingolipid
  50. GC40016 Ganglioside GM2 Mixture (sodium salt)

    单唾液酸神经节苷脂GM2; GM2; Monosialoganglioside GM2

     A mixture of ganglioside GM2
  51. GC52487 Ganglioside GM4 (chicken egg) (ammonium salt)

    Ganglioside G7, Monosialoganglioside GM4

     A sphingolipid

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