Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for Neuroscience

Cat.No. 产品名称 Information
GC47060 CAY10762 An inhibitor of MAGL
GC49094 CAY10781 An NRP-1/VEGF-A interaction inhibitor
GC49080 CAY10786

GPR52-IN-43
A GPR52 antagonist
GC49226 CAY10787

Δ3,5-Cholestadien-7-one, CSD, NSC 18180, NSC 134914
An oxysterol and a negative allosteric modulator of GABA_A receptors
GC52006 CB-096 An inhibitor of RAN translation
GC18695 CB-86 An Analytical Reference Standard
GC12899 CBiPES hydrochloride positive allosteric modulator of the mGlu2 receptor
GC50126 CC4

野决明定
High affinity and subtype-selective α6β2 and α4β2 nAChR partial agonist
GC43213 CCK (26-30) (sulfated)

N-Acetyl Cholecystokinin (26-30)
An N-terminal fragment of CCK
GC43214 CCK (26-31) (non-sulfated)

N-Acetyl Cholecystokinin (26-31), (non-sulfated)
An N-terminal fragment of CCK
GC18553 CCK (26-31) (sulfated)

N-Acetyl Cholecystokinin (26-31), (sulfated)
An N-terminal fragment of CCK
GC18384 CCK (27-33) (non-sulfated)

Cholecystokinin (27-33) (non-sulfated)
A C-terminal fragment of CCK
GC43215 CCK Octapeptide (non-sulfated), (trifluoroacetate salt)

Cholecystokinin Octapeptide (26-33), Pancreozymin (C-terminal) Octapeptide, SQ 19,265
A non-sulfated CCK peptide
GC31558 CCK-A receptor inhibitor 1
CCK-Areceptorinhibitor1是一种缩胆囊素A(cholecystokininA,CCK-A)受体抑制剂，IC50为340nM。
GC30752 CCK-B Receptor Antagonist 1

(Rac)-Netazepide; (Rac)-YF 476; (Rac)-YM-220
CCK-B Receptor Antagonist 1 是胆囊收缩素 B (CCK-B) 受体的拮抗剂，具有减少胃酸分泌的潜力。
GC38746 CCK-B Receptor Antagonist 2 CCK-B Receptor Antagonist 2，化合物 15b，是有效的口服活性 Gastrin/CCK-B 拮抗剂，IC50 值为 0.43 nM。 CCK-B Receptor Antagonist 2 还抑制 Gastrin/CCK-A 活性，IC50 为 1.82 μM。
GC12119 CCMI

AVL-3288; UCI-4083
CCMI (AVL-3288) 是一种有效且选择性的 α7 nAChR 阳性变构调节剂，不通过正构位点结合或激活 α7 nAChRs，并导致激动剂诱导的 α7 nAChRs 电流显着正向调节。
GC43216 CCR4 Antagonist (hydrochloride)

C-021
A CCR4 antagonist
GC31255 CDD0102 (CDD0102A)

CDD0102A
CDD0102 (CDD0102A) 是一种有效的 M1 毒蕈碱受体激动剂。
GC43220 Cdk5 Substrate

Cyclin-dependent kinase 5 Substrate
A peptide substrate of Cdk5
GC10422 CDPPB

3-氰基-N-(1,3-二苯基吡唑-5-基)苯甲酰胺
A positive allosteric modulator of mGluR5
GC14475 Celecoxib

塞来昔布; SC 58635
Celecoxib是一种高度选择性的环氧合酶-2（COX-2）抑制剂，IC₅₀值为40nM。
GC49152 Celecoxib Carboxylic Acid

羧酸塞来昔布
An inactive metabolite of celecoxib
GC68849 Celecoxib-d3

SC 58635-d₃
Celecoxib-d3 是 Celecoxib 的氘代物。Celecoxib 是一种选择性的 COX-2 抑制剂，IC50 为 40 nM。
GC47070 Celecoxib-d7

塞来昔布-D7,SC 58635-d7
An internal standard for the quantification of celecoxib
GC31283 Centanafadine (EB-1020)

(1R,5S)-1-(2-萘基)-3-氮杂双环[3.1.0]己烷,EB-1020
Centanafadine (EB-1020) 是双重去甲肾上腺素 (NE)/多巴胺 (DA) 转运蛋白抑制剂，也抑制血清素转运蛋白，对人 NE、DA 和血清素转运蛋白的 IC50 分别为 6 nM、38 nM 和 83 nM。
GC31175 Centanafadine hydrochloride (EB-1020 (hydrochloride))

EB-1020 hydrochloride
Centanafadine (hydrochloride) 是去甲肾上腺素 (NE)/多巴胺 (DA) 转运蛋白双重抑制剂，也抑制血清素转运蛋白，对人 NE、DA 和血清素转运蛋白的 IC50 分别为 6 nM、38 nM 和 83 nM。
GC52486 Ceramide Phosphoethanolamine (bovine)

N-Acyl Ceramide Phosphoethanolamine (d18:1/acyl mixture), CPE, N-acyl-D-erythro-Sphingosylphosphorylethanolamine
A sphingolipid
GC43229 Ceramide Phosphoethanolamines (bovine) Ceramide phosphoethanolamine (CPE) is an analog of sphingomyelin that contains ethanolamine rather than choline as the head group.
GC63961 Cerlapirdine

SAM-531; PF-05212365
Cerlapirdine (SAM-531, PF-05212365) 是一种选择性和有效的 5-羟色胺 6 (5-HT6) 受体的完全拮抗剂。Cerlapirdine 具有研究阿尔茨海默病的潜力。
GC30008 Ceruletide (Caerulein)

雨蛙素; Caerulein; Cerulein; FI-6934
Ceruletide 作为一种十肽和一种有效的胆囊收缩剂，对人类和动物的胆囊肌肉和胆管具有直接的痉挛作用。
GC10185 Cetirizine

西替利嗪
西替利嗪是一种第二代抗组胺药，是羟嗪的羧化代谢物，是一种特异性的、具有口服活性的长效组胺 H1 受体拮抗剂。
GC67944 Cetirizine D4 Cetirizine D4 是Cetirizine 的氘代物。Cetirizine 是羟嗪的羧化代谢物，是第二代抗组胺药。Cetirizine 是一种特异的、口服有效的、H1 受体的长效拮抗剂。Cetirizine 标记抗过敏特性，抑制过敏反应期间嗜酸性粒细胞趋化。
GC35655 Cetirizine D4 dihydrochloride

盐酸西替利嗪 D4
Cetirizine D4二盐酸盐是Cetirizine氘代化合物标准品。
GC68409 Cetirizine D8 Cetirizine D8 是Cetirizine 的氘代物。Cetirizine 是羟嗪的羧化代谢物，是第二代抗组胺药。Cetirizine 是一种特异的、口服有效的、H1 受体的长效拮抗剂。Cetirizine 标记抗过敏特性，抑制过敏反应期间嗜酸性粒细胞趋化。
GC35656 Cetirizine D8 dihydrochloride

盐酸西替利嗪 D8
An internal standard for the quantification of cetirizine,(R)-cetirizine, and (S)-cetirizine
GC11009 Cetirizine DiHCl

盐酸西替利嗪; P071
A selective histamine H₁ receptor antagonist
GC60691 Cetirizine Impurity C

西替利嗪杂质C
CetirizineImpurityC是Cetirizine的一种杂质。Cetirizine是羟嗪的羧化代谢物，是第二代抗组胺剂。Cetirizine是一种特异的、具有口服活性的H1受体(histamineH1-receptor)的长效拮抗剂。
GC64577 Cetirizine Impurity C dihydrochloride

盐酸西替利嗪EP杂质C二盐酸盐
Cetirizine Impurity C dihydrochloride 是 Cetirizine 的一种杂质。Cetirizine 是羟嗪的羧化代谢物，是第二代抗组胺剂。Cetirizine 是一种特异的、具有口服活性的 H1 受体 (histamine H1-receptor) 的长效拮抗剂。
GC14215 Cevimeline

西维美林; AF102B
A muscarinic receptor agonist
GC43232 Cevimeline (hydrochloride)

盐酸西维美林; AF102B hydrochloride
A muscarinic receptor agonist
GC17157 Cevimeline hydrochloride hemihydrate

盐酸西维美林半水合物; SNI-2011; AF102B hydrochloride hemihydrate
Cevimeline hydrochloride hemihydrate (SNI-2011) 是乙酰胆碱的奎宁环衍生物，是一种选择性和口服活性的毒蕈碱 M1 和 M3 受体激动剂。
GC18079 CFM-2 CFM-2 是一种有效且选择性的非竞争性 AMPAR 拮抗剂。
GC30995 CGP 25454A CGP25454A是一个新颖和选择性的突触前多巴胺自受体拮抗剂。
GC35669 CGP 36742

SGS-742
A GABA_B receptor antagonist
GC15950 CGP 52411

DAPH
A phthalimide with diverse biological activities
GC16947 CGP 52432

4-苄氧基苯基异硫氰酸酯
A GABA_B receptor antagonist
GC33751 CGP11952 CGP11952是一种三唑基Benzaphenon。CGP11952是一种苯二氮卓类(benzodiazepine)衍生物。
GC52438 CGRP (8-37) (mouse, rat) (trifluoroacetate salt)

Calcitonin Gene-Related Peptide (8-37), CGRP8-37, VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF-NH2
A CGRP receptor antagonist
GC16147 CGRP 8-37 (human)

降钙素基因相关肽片段8-37人体,Human α-CGRP (8-37)
CGRP 8-37 (human)是一种高选择性的CGRP受体拮抗剂。