Kallidin (380-389) (human, porcine, bovine) (trifluoroacetate salt) is a short-lived kinin peptide that stimulates net Na+ influx and DNA synthesis [1]. Kallidin (380-389) can reduce the resistance of the airway blood vessels and promote vasodilation by acting on the B2 receptor[2]. Kallidin (380-389) has been widely used to stimulate the release of prolactin (PRL) in the rat anterior pituitary cells [3].
References:
[1] Owen N E, Villereal M L. Lys-bradykinin stimulates Na+ influx and DNA synthesis in cultured human fibroblasts[J]. Cell, 1983, 32(3): 979-985.
[2] Corfield D R, Webber S E, Hanafi Z, et al. The actions of bradykinin and lys-bradykinin on tracheal blood flow and smooth muscle in anaesthetized sheep[J]. Pulmonary pharmacology, 1991, 4(2): 85-90.
[3] Kuan S I, Judd A M, Jarvis W D, et al. Physiological and biochemical effects of bradykinin and lys-bradykinin in pituitary cells[J]. Molecular and cellular endocrinology, 1990, 72(3): 239-246.
Kallidin (380-389) (human, porcine, bovine) (trifluoroacetate salt)是一种短寿命的激肽，可刺激净Na+内流和DNA合成[1]。Kallidin (380-389)通过作用于B2受体，可降低气道血管的阻力并促进血管舒张[2]。Kallidin (380-389)已被广泛用于刺激大鼠腺垂体细胞中催乳(PRL)的释放[3]。